CONFOCAL LASER ENDOMICROSCOPY IN DIAGNOSING GASTRIC AND ESOPHAGEAL LESIONS AND IN POST-RFA SURVEILLANCE OF PATIENTS WITH BARRETT'S ESOPHAGUS

2018 ◽  
Author(s):  
J Krajciova ◽  
M Kollar ◽  
J Maluskova ◽  
Z Vackova ◽  
J Spicak ◽  
...  
Keyword(s):  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
Confocal Laser Endomicroscopy ◽  
Confocal Laser

scholarly journals Probe-based confocal laser endomicroscopy and Barrett's esophagus – just a scientific toy or significant improvement in diagnosis?

2021 ◽  
Author(s):  
Luka Vranić ◽  
Tin Nadarević ◽  
Davor Štimac
Keyword(s):  
Diagnostic Accuracy ◽  
Real Time ◽  
Barrett’S Esophagus ◽  
Predictive Value ◽  
Barrett's Esophagus ◽  
High Reliability ◽  
Confocal Laser Endomicroscopy ◽  
Confocal Laser ◽  
Imaging Method ◽  
Increased Risk

Background: Barrett’s esophagus (BE) requires surveillance to identify potential neoplasia at early stage. Standard surveillance regimen includes random four-quadrant biopsies by Seattle protocol. Main limitations of random biopsies are high risk of sampling error, difficulties in histology interpretation, common inadequate classification of pathohistological changes, increased risk of bleeding and time necessary to acquire the final diagnosis. Probe-based confocal laser endomicroscopy (pCLE) has emerged as a potential tool with an aim to overcome these obvious limitations. Summary: pCLE represents real-time microscopic imaging method that offers evaluation of epithelial and subepithelial structures with 1000-fold magnification. In theory, pCLE has potential to eliminate the need for biopsy in BE patient. The main advantages would be real-time diagnosis and decision making, greater diagnostic accuracy and to evaluate larger area compared to random biopsies. Clinical pCLE studies in esophagus show high diagnostic accuracy and its high negative predictive value offers high reliability and confidence to exclude dysplastic and neoplastic lesions. However, it still cannot replace histopathology due to lower positive predictive value and sensitivity. Key messages: Despite promising results, its role in routine use in patients with Barrett’s esophagus remains questionable primarily due to lack of well-organized double-blind randomized trials.

Mo1544 Can Novel Probe Based Confocal Laser Endomicroscopy (pCLE) Criteria Improve Accuracy for Diagnosing Dysplasia in Barrett's Esophagus (BE)?

2011 ◽  
Vol 73 (4) ◽  
pp. AB381
Author(s):  
Mandeep Singh ◽  
Neil Gupta ◽  
Srinivas Gaddam ◽  
Andrew Overhiser ◽  
Sachin B. Wani ◽  
...  
Keyword(s):  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
Confocal Laser Endomicroscopy ◽  
Confocal Laser ◽  
Improve Accuracy

Tu1078 The Role of Confocal Laser Endomicroscopy in the Management of Patients With Barrett's Esophagus: A Clinical Evidence-Based Consensus Report

2014 ◽  
Vol 146 (5) ◽  
pp. S-746
Author(s):  
Kenneth K. Wang ◽  
Razvan Arsenescu ◽  
Helga Bertani ◽  
Fabrice Caillol ◽  
David L. Carr-Locke ◽  
...  
Keyword(s):  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
Clinical Evidence ◽  
Confocal Laser Endomicroscopy ◽  
Confocal Laser ◽  
Evidence Based ◽  
Consensus Report

239 Computer Aided Diagnosis of Barrett's Esophagus Using Confocal Laser Endomicroscopy: Preliminary Data

2012 ◽  
Vol 75 (4) ◽  
pp. AB126 ◽  
Author(s):  
Enrico Grisan ◽  
Elisa Veronese ◽  
Giorgio Diamantis ◽  
Cristina Trovato ◽  
Cristiano Crosta ◽  
...  
Keyword(s):  
Barrett’S Esophagus ◽  
Preliminary Data ◽  
Barrett's Esophagus ◽  
Computer Aided Diagnosis ◽  
Confocal Laser Endomicroscopy ◽  
Confocal Laser ◽  
Computer Aided ◽  
Aided Diagnosis
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