scholarly journals Endothelial nitric oxide synthase overexpression attenuates congestive heart failure in mice

2003 ◽  
Vol 100 (8) ◽  
pp. 4891-4896 ◽  
Author(s):  
S. P. Jones ◽  
J. J. M. Greer ◽  
R. van Haperen ◽  
D. J. Duncker ◽  
R. de Crom ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Heart Failure ◽  
Congestive Heart Failure ◽  
Nitric Oxide Synthase ◽  
Endothelial Nitric Oxide Synthase ◽  
Oxide Synthase ◽  
Endothelial Nitric Oxide

scholarly journals Effect of the Asp 298 Variant of Endothelial Nitric Oxide Synthase on Survival for Patients With Congestive Heart Failure

Circulation ◽  
2003 ◽  
Vol 107 (12) ◽  
pp. 1598-1602 ◽  
Author(s):  
Dennis M. McNamara ◽  
Richard Holubkov ◽  
Lisa Postava ◽  
Ravi Ramani ◽  
Karen Janosko ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Heart Failure ◽  
Congestive Heart Failure ◽  
Nitric Oxide Synthase ◽  
Endothelial Nitric Oxide Synthase ◽  
Oxide Synthase ◽  
Endothelial Nitric Oxide

Localization of endothelial nitric oxide synthase in the normal and failing human atrial myocardium

1996 ◽  
Vol 54 ◽  
pp. 786-787
Author(s):  
Chi-Ming Wei ◽  
Margarita Bracamonte ◽  
Shi-Wen Jiang ◽  
Richard C. Daly ◽  
Christopher G.A. McGregor ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Heart Failure ◽  
Nitric Oxide Synthase ◽  
Endothelial Nitric Oxide Synthase ◽  
Cardiac Tissues ◽  
Mammalian Tissues ◽  
End Stage Heart Failure ◽  
End Stage ◽  
Oxide Synthase ◽  
Endothelial Nitric Oxide

Nitric oxide (NO) is a potent endothelium-derived relaxing factor which also may modulate cardiomyocyte inotropism and growth via increasing cGMP. While endothelial nitric oxide synthase (eNOS) isoforms have been detected in non-human mammalian tissues, expression and localization of eNOS in the normal and failing human myocardium are poorly defined. Therefore, the present study was designed to investigate eNOS in human cardiac tissues in the presence and absence of congestive heart failure (CHF).Normal and failing atrial tissue were obtained from six cardiac donors and six end-stage heart failure patients undergoing primary cardiac transplantation. ENOS protein expression and localization was investigated utilizing Western blot analysis and immunohistochemical staining with the polyclonal rabbit antibody to eNOS (Transduction Laboratories, Lexington, Kentucky).

scholarly journals Development of Heart Failure and Congenital Septal Defects in Mice Lacking Endothelial Nitric Oxide Synthase

Circulation ◽  
2002 ◽  
Vol 106 (7) ◽  
pp. 873-879 ◽  
Author(s):  
Qingping Feng ◽  
Wei Song ◽  
Xiangru Lu ◽  
Joel A. Hamilton ◽  
Ming Lei ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Heart Failure ◽  
Nitric Oxide Synthase ◽  
Endothelial Nitric Oxide Synthase ◽  
Septal Defects ◽  
Oxide Synthase ◽  
Endothelial Nitric Oxide

Steady endothelial nitric oxide synthase expression in heart failure

2007 ◽  
Vol 62 (3) ◽  
pp. 261-264 ◽  
Author(s):  
P.V. ENNEZAT ◽  
E. VAN BELLE ◽  
P. ASSEMAN ◽  
A. COHEN-SOLAL ◽  
T. EVANS ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Heart Failure ◽  
Nitric Oxide Synthase ◽  
Endothelial Nitric Oxide Synthase ◽  
Oxide Synthase ◽  
Endothelial Nitric Oxide
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