scholarly journals Effect of the Asp 298 Variant of Endothelial Nitric Oxide Synthase on Survival for Patients With Congestive Heart Failure

Circulation ◽  
2003 ◽  
Vol 108 (15) ◽  
Author(s):  
Giuseppe Maiolino ◽  
Gian Paolo Rossi
2003 ◽  
Vol 100 (8) ◽  
pp. 4891-4896 ◽  
Author(s):  
S. P. Jones ◽  
J. J. M. Greer ◽  
R. van Haperen ◽  
D. J. Duncker ◽  
R. de Crom ◽  
...  

Circulation ◽  
2003 ◽  
Vol 107 (12) ◽  
pp. 1598-1602 ◽  
Author(s):  
Dennis M. McNamara ◽  
Richard Holubkov ◽  
Lisa Postava ◽  
Ravi Ramani ◽  
Karen Janosko ◽  
...  

Author(s):  
Chi-Ming Wei ◽  
Margarita Bracamonte ◽  
Shi-Wen Jiang ◽  
Richard C. Daly ◽  
Christopher G.A. McGregor ◽  
...  

Nitric oxide (NO) is a potent endothelium-derived relaxing factor which also may modulate cardiomyocyte inotropism and growth via increasing cGMP. While endothelial nitric oxide synthase (eNOS) isoforms have been detected in non-human mammalian tissues, expression and localization of eNOS in the normal and failing human myocardium are poorly defined. Therefore, the present study was designed to investigate eNOS in human cardiac tissues in the presence and absence of congestive heart failure (CHF).Normal and failing atrial tissue were obtained from six cardiac donors and six end-stage heart failure patients undergoing primary cardiac transplantation. ENOS protein expression and localization was investigated utilizing Western blot analysis and immunohistochemical staining with the polyclonal rabbit antibody to eNOS (Transduction Laboratories, Lexington, Kentucky).


Circulation ◽  
2002 ◽  
Vol 106 (7) ◽  
pp. 873-879 ◽  
Author(s):  
Qingping Feng ◽  
Wei Song ◽  
Xiangru Lu ◽  
Joel A. Hamilton ◽  
Ming Lei ◽  
...  

2007 ◽  
Vol 62 (3) ◽  
pp. 261-264 ◽  
Author(s):  
P.V. ENNEZAT ◽  
E. VAN BELLE ◽  
P. ASSEMAN ◽  
A. COHEN-SOLAL ◽  
T. EVANS ◽  
...  

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