scholarly journals Live agent preference and social action monitoring in the macaque mid-superior temporal sulcus region

2021 ◽  
Vol 118 (44) ◽  
pp. e2109653118
Author(s):  
Taihei Ninomiya ◽  
Atsushi Noritake ◽  
Masaki Isoda
Keyword(s):  
Social Action ◽  
Social Intelligence ◽  
Predictive Coding ◽  
Population Level ◽  
Mental States ◽  
Superior Temporal Sulcus ◽  
Middle Part ◽  
Temporoparietal Junction ◽  
Partner Type ◽  
Functional Brain Mapping

Mentalizing, the ability to infer the mental states of others, is a cornerstone of adaptive social intelligence. While functional brain mapping of human mentalizing has progressed considerably, its evolutionary signature in nonhuman primates remains debated. The discovery that the middle part of the macaque superior temporal sulcus (mid-STS) region has a connectional fingerprint most similar to the human temporoparietal junction (TPJ)—a crucial node in the mentalizing network—raises the possibility that these cortical areas may also share basic functional properties associated with mentalizing. Here, we show that this is the case in aspects of a preference for live social interactions and in a theoretical framework of predictive coding. Macaque monkeys were trained to perform a turn-taking choice task with another real monkey partner sitting directly face-to-face or a filmed partner appearing in prerecorded videos. We found that about three-fourths of task-related mid-STS neurons exhibited agent-dependent activity, most responding selectively or preferentially to the partner’s action. At the population level, activities of these partner-type neurons were significantly greater under live-partner compared to video-recorded–partner task conditions. Furthermore, a subset of the partner-type neurons responded proactively when predictions about the partner’s action were violated. This prediction error coding was specific to the action domain; almost none of the neurons signaled error in the prediction of reward. The present findings highlight unique roles of the macaque mid-STS at the single-neuron level and further delineate its functional parallels with the human TPJ in social cognitive processes associated with mentalizing.

scholarly journals The Interaction Between Caudate Nucleus and Regions Within the Theory of Mind Network as a Neural Basis for Social Intelligence

2021 ◽  
Vol 15 ◽  
Author(s):  
Mikhail Votinov ◽  
Artem Myznikov ◽  
Maya Zheltyakova ◽  
Ruslan Masharipov ◽  
Alexander Korotkov ◽  
...  
Keyword(s):  
Theory Of Mind ◽  
Caudate Nucleus ◽  
Cognitive Processes ◽  
Social Intelligence ◽  
Functional Integration ◽  
Mental States ◽  
Neural Basis ◽  
Caudate Nuclei ◽  
Structural Peculiarity ◽  
The Right

The organization of socio-cognitive processes is a multifaceted problem for which many sophisticated concepts have been proposed. One of these concepts is social intelligence (SI), i.e., the set of abilities that allow successful interaction with other people. The theory of mind (ToM) human brain network is a good candidate for the neural substrate underlying SI since it is involved in inferring the mental states of others and ourselves and predicting or explaining others’ actions. However, the relationship of ToM to SI remains poorly explored. Our recent research revealed an association between the gray matter volume of the caudate nucleus and the degree of SI as measured by the Guilford-Sullivan test. It led us to question whether this structural peculiarity is reflected in changes to the integration of the caudate with other areas of the brain associated with socio-cognitive processes, including the ToM system. We conducted seed-based functional connectivity (FC) analysis of resting-state fMRI data for 42 subjects with the caudate as a region of interest. We found that the scores of the Guilford-Sullivan test were positively correlated with the FC between seeds in the right caudate head and two clusters located within the right superior temporal gyrus and bilateral precuneus. Both regions are known to be nodes of the ToM network. Thus, the current study demonstrates that the SI level is associated with the degree of functional integration between the ToM network and the caudate nuclei.

scholarly journals Moral judgement by the disconnected left and right cerebral hemispheres: a split-brain investigation

2017 ◽  
Vol 4 (7) ◽  
pp. 170172 ◽  
Author(s):  
Conor M. Steckler ◽  
J. Kiley Hamlin ◽  
Michael B. Miller ◽  
Danielle King ◽  
Alan Kingstone
Keyword(s):  
Brain Research ◽  
Right Hemisphere ◽  
Mental States ◽  
Brain Regions ◽  
Moral Judgement ◽  
Temporoparietal Junction ◽  
Split Brain ◽  
Moral Judgements ◽  
The Right ◽  
Necessary And Sufficient

Owing to the hemispheric isolation resulting from a severed corpus callosum, research on split-brain patients can help elucidate the brain regions necessary and sufficient for moral judgement. Notably, typically developing adults heavily weight the intentions underlying others' moral actions, placing greater importance on valenced intentions versus outcomes when assigning praise and blame. Prioritization of intent in moral judgements may depend on neural activity in the right hemisphere's temporoparietal junction, an area implicated in reasoning about mental states. To date, split-brain research has found that the right hemisphere is necessary for intent-based moral judgement. When testing the left hemisphere using linguistically based moral vignettes, split-brain patients evaluate actions based on outcomes, not intentions. Because the right hemisphere has limited language ability relative to the left, and morality paradigms to date have involved significant linguistic demands, it is currently unknown whether the right hemisphere alone generates intent-based judgements. Here we use nonlinguistic morality plays with split-brain patient J.W. to examine the moral judgements of the disconnected right hemisphere, demonstrating a clear focus on intent. This finding indicates that the right hemisphere is not only necessary but also sufficient for intent-based moral judgement, advancing research into the neural systems supporting the moral sense.

scholarly journals Toward a Compassionate Intersectional Neuroscience: Increasing Diversity and Equity in Contemplative Neuroscience

2020 ◽  
Vol 11 ◽  
Author(s):  
Helen Y. Weng ◽  
Mushim P. Ikeda ◽  
Jarrod A. Lewis-Peacock ◽  
Maria T. Chao ◽  
Duana Fullwiley ◽  
...  
Keyword(s):  
Machine Learning ◽  
Ethnic Minorities ◽  
Social Action ◽  
Sexual Minorities ◽  
Learning Algorithms ◽  
Mental States ◽  
Research Process ◽  
Machine Learning Algorithms ◽  
Individual Level ◽  
Contemplative Neuroscience

Mindfulness and compassion meditation are thought to cultivate prosocial behavior. However, the lack of diverse representation within both scientific and participant populations in contemplative neuroscience may limit generalizability and translation of prior findings. To address these issues, we propose a research framework called Intersectional Neuroscience which adapts research procedures to be more inclusive of under-represented groups. Intersectional Neuroscience builds inclusive processes into research design using two main approaches: 1) community engagement with diverse participants, and 2) individualized multivariate neuroscience methods to accommodate neural diversity. We tested the feasibility of this framework in partnership with a diverse U.S. meditation center (East Bay Meditation Center, Oakland, CA). Using focus group and community feedback, we adapted functional magnetic resonance imaging (fMRI) screening and recruitment procedures to be inclusive of participants from various under-represented groups, including racial and ethnic minorities, gender and sexual minorities, people with disabilities, neuropsychiatric disorders, and/or lower income. Using person-centered screening and study materials, we recruited and scanned 15 diverse meditators (80% racial/ethnic minorities, 53% gender and sexual minorities). The participants completed the EMBODY task – which applies individualized machine learning algorithms to fMRI data – to identify mental states during breath-focused meditation, a basic skill that stabilizes attention to support interoception and compassion. All 15 meditators’ unique brain patterns were recognized by machine learning algorithms significantly above chance levels. These individualized brain patterns were used to decode the internal focus of attention throughout a 10-min breath-focused meditation period, specific to each meditator. These data were used to compile individual-level attention profiles during meditation, such as the percentage time attending to the breath, mind wandering, or engaging in self-referential processing. This study provides feasibility of employing an intersectional neuroscience approach to include diverse participants and develop individualized neural metrics of meditation practice. Through inclusion of more under-represented groups while developing reciprocal partnerships, intersectional neuroscience turns the research process into an embodied form of social action.

scholarly journals Regional Specialization and Coordination Within the Network for Perceiving and Knowing About Others

2019 ◽  
Author(s):  
Aidas Aglinskas ◽  
Scott L Fairhall
Keyword(s):  
Cognitive Processes ◽  
Imaging Study ◽  
Superior Temporal Sulcus ◽  
Brain Regions ◽  
Knowledge Network ◽  
System Level ◽  
Angular Gyrus ◽  
Semantic Retrieval ◽  
Temporoparietal Junction ◽  
Cognitive Domains

Abstract Seeing familiar faces prompts the recall of diverse kinds of person-related knowledge. How this information is encoded within the well-characterized face-/person-selective network remains an outstanding question. In this functional magnetic resonance imaging study, participants rated famous faces in 10 tasks covering 5 domains of person knowledge (social, episodic, semantic, physical, and nominal). Comparing different cognitive domains enabled us to 1) test the relative roles of brain regions in specific cognitive processes and 2) apply a multivariate network-level representational similarity analysis (NetRSA) to gain insight into underlying system-level organization. Comparing across cognitive domains revealed the importance of multiple domains in most regions, the importance of social over nominal knowledge in the anterior temporal lobe, and the functional subdivision of the temporoparietal junction into perceptual superior temporal sulcus and knowledge-related angular gyrus. NetRSA revealed a strong divide between regions implicated in ``default-mode” cognition and the fronto-lateral elements that coordinated more with ``core” perceptual components (fusiform/occipital face areas and posterior superior temporal sulcus). NetRSA also revealed a taxonomy of cognitive processes, with semantic retrieval being more similar to episodic than nominal knowledge. Collectively, these results illustrate the importance of coordinated activity of the person knowledge network in the instantiation of the diverse cognitive capacities of this system.

scholarly journals Asking ‘why?’ enhances theory of mind when evaluating harm but not purity violations

2019 ◽  
Vol 14 (7) ◽  
pp. 699-708 ◽  
Author(s):  
James A Dungan ◽  
Liane Young
Keyword(s):  
Theory Of Mind ◽  
Mental States ◽  
Brain Regions ◽  
Judgment Task ◽  
Moral Judgments ◽  
Moral Norms ◽  
Temporoparietal Junction ◽  
Task Instructions ◽  
Right Temporoparietal Junction ◽  
The Right

Abstract Recent work in psychology and neuroscience has revealed important differences in the cognitive processes underlying judgments of harm and purity violations. In particular, research has demonstrated that whether a violation was committed intentionally vs accidentally has a larger impact on moral judgments of harm violations (e.g. assault) than purity violations (e.g. incest). Here, we manipulate the instructions provided to participants for a moral judgment task to further probe the boundary conditions of this intent effect. Specifically, we instructed participants undergoing functional magnetic resonance imaging to attend to either a violator’s mental states (why they acted that way) or their low-level behavior (how they acted) before delivering moral judgments. Results revealed that task instructions enhanced rather than diminished differences between how harm and purity violations are processed in brain regions for mental state reasoning or theory of mind. In particular, activity in the right temporoparietal junction increased when participants were instructed to attend to why vs how a violator acted to a greater extent for harm than for purity violations. This result constrains the potential accounts of why intentions matter less for purity violations compared to harm violations and provide further insight into the differences between distinct moral norms.

scholarly journals Neural correlates of theory-of-mind are associated with variation in children’s everyday social cognition

2019 ◽  
Vol 14 (6) ◽  
pp. 579-589 ◽  
Author(s):  
Cora E Mukerji ◽  
Sarah Hope Lincoln ◽  
David Dodell-Feder ◽  
Charles A Nelson ◽  
Christine I Hooker
Keyword(s):  
Social Cognition ◽  
Theory Of Mind ◽  
Social Cognitive ◽  
Mental States ◽  
False Belief ◽  
School Age Children ◽  
Cognitive Behavior ◽  
School Age ◽  
Temporoparietal Junction ◽  
False Belief Reasoning

ABSTRACT Theory of mind (ToM), the capacity to reason about others’ mental states, is central to healthy social development. Neural mechanisms supporting ToM may contribute to individual differences in children’s social cognitive behavior. Employing a false belief functional magnetic resonance imaging paradigm, we identified patterns of neural activity and connectivity elicited by ToM reasoning in school-age children (N = 32, ages 9–13). Next, we tested relations between these neural ToM correlates and children’s everyday social cognition. Several key nodes of the neural ToM network showed greater activity when reasoning about false beliefs (ToM condition) vs non-mentalistic false content (control condition), including the bilateral temporoparietal junction (RTPJ and LTPJ), precuneus (PC) and right superior temporal sulcus. In addition, children demonstrated task-modulated changes in connectivity among these regions to support ToM relative to the control condition. ToM-related activity in the PC was negatively associated with variation in multiple aspects of children’s social cognitive behavior. Together, these findings elucidate how nodes of the ToM network act and interact to support false belief reasoning in school-age children and suggest that neural ToM mechanisms are linked to variation in everyday social cognition.

Intentionality in Parenting Styles of Parents and Student-Facilitators’ Reflections: A Hermeneutical-Deconstruction Analysis

2012 ◽  
Vol 1 (1) ◽  
Author(s):  
Vicky Discaya Isonza
Keyword(s):  
Parenting Style ◽  
Parenting Styles ◽  
Social Action ◽  
Mental States ◽  
Unexpected Events ◽  
Folk Belief ◽  
Approach To Learning ◽  
Authoritarian Parenting ◽  
The Family ◽  
Authoritarian Parenting Style

In the context of a seminar-workshop on parenting styles, the intentionality of parent-participants and student-facilitators was explored over the goal of enhancing the welfare and functioning of children. Student-facilitators conducted learning activities and processed discussions on care and discipline issues. Using the mixed method, quantitative and qualitative analyses were drawn. A Likert scale measured democratic and authoritarian dimensions in parenting style. Through the lens of postmodern paradigm, the hermeneutic-deconstruction analysis illuminated the phenomena on parents’ understanding of parenting styles and student-facilitators’ learning outcomes based on their reflections. In conclusion, the celebration of special occasions is the ‘signified’ indicant of parents’ nurturing in the family. Responsiveness and communication are ‘signifiers’ (not emphasized /hidden). Their ‘folk belief’ concepts are operatives of mental states that reflect an authoritarian parenting style; but group-acknowledgements in discussions can move them to favor the democratic style. Parents value a norm-based rationality on discipline of children. In the deconstruction process unexpected events are laid bare. This contributes an authentic learning opportunity for students to expand a social consciousness that rouses the move for social action. Implications of a postmodern analytical approach to learning intervention for parents, and the pedagogic method of reflective analysis and social action are discussed. Keywords - intentionality, parenting style, hermeneuticalde construction analysis, pedagogy, social action

Urban development and health inequalities

2002 ◽  
Vol 30 (59_suppl) ◽  
pp. 59-62
Author(s):  
Mark McCarthy
Keyword(s):  
Urban Development ◽  
Social Action ◽  
Urban Areas ◽  
Green Space ◽  
Social Inequalities ◽  
Population Level ◽  
Social Differences ◽  
Cultural Experiences ◽  
The Life Course

Urban development has historically been seen as both a cause and solution for social inequalities in health. However, environmental and individual gradients within urban areas occur everywhere, and are resistant to change. Environments are infl uenced by the degree and type of industrialization, quality of housing, accessibility to green space and - of increasing concern - transport. Individual behaviour, however, also contributes to social differences, both through migration and by the effects on individuals of cultural experiences through the life-course. Reduction on inequalities may be possible through larger social action, for example urban regeneration. There remains an important role for public health in addressing determinants of health at the population level.

scholarly journals Right Temporoparietal Junction Encodes Mental Experience of Others More Than Evaluating False Versus True Belief

2021 ◽  
Author(s):  
Branden J. Bio ◽  
Arvid Guterstam ◽  
Mark Pinsk ◽  
Andrew I. Wilterson ◽  
Michael S. A. Graziano
Keyword(s):  
True Belief ◽  
Mental States ◽  
False Belief ◽  
Temporoparietal Junction ◽  
Cartoon Character ◽  
Visual Reaction ◽  
Alternative Hypotheses ◽  
Right Temporoparietal Junction ◽  
Cortical Regions ◽  
The Right

When people make inferences about other people's minds, called theory of mind (ToM), a network in the cerebral cortex becomes active. ToM experiments sometimes use the false belief task, in which subjects decide whether a story character believes A or B. The "false" belief occurs if the character believes A when B is true. We devised a version in which subjects judged whether a cartoon head "believed" a ball to be in box 1 or box 2. The task was a visual, reaction time version of a ToM task. We proposed two alternative hypotheses. In hypothesis 1, cortical regions of interest within the ToM network should distinguish between false and true belief trials, reflecting outside information that the subjects have about the cartoon character. In hypothesis 2, the ToM network should distinguish between conditions only if the subjects think that the cartoon character can distinguish between the conditions, thus reflecting a model of the internal contents of the cartoon character's mind. The results supported hypothesis 2. Events that the cartoon could not "see" did not affect activity in the ToM network; the same events, when the cartoon could apparently "see" them, significantly affected activity in the right temporoparietal junction (TPJ). The results support the view that the right TPJ participates in modeling the mental states of others, rather than in evaluating the accuracy of the beliefs of others, and may help explain why previous experiments showed mixed results when directly comparing false belief to true belief conditions.

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