scholarly journals Infectious murine leukemia virus from DNA of virus-negative AKR mouse embryo cells.

1978 ◽  
Vol 75 (11) ◽  
pp. 5539-5543 ◽  
Author(s):  
D. R. Lowy
Keyword(s):  
Mouse Embryo ◽  
Murine Leukemia Virus ◽  
Leukemia Virus ◽  
Embryo Cells ◽  
Murine Leukemia

Permissiveness to murine leukemia, virus expression during preimplantation and early postimplantation mouse development

Development ◽  
1990 ◽  
Vol 109 (3) ◽  
pp. 655-665
Author(s):  
P. Savatier ◽  
J. Morgenstern ◽  
R.S. Beddington
Keyword(s):  
Mouse Embryo ◽  
Murine Leukemia Virus ◽  
Inner Cell Mass ◽  
Leukemia Virus ◽  
Cell Mass ◽  
Lacz Gene ◽  
Mouse Development ◽  
Beta Galactosidase ◽  
Murine Leukemia

Permissiveness to Moloney Murine Leukemia Virus (MoMuLV) expression was examined during preimplantation and early postimplantation development of the mouse embryo. Blastocysts and 8th, 9th and 10th day postimplantation embryos were infected in vitro with a MoMuLV-based retroviral vector expressing the lacZ gene driven off an internal rat beta-actin promoter. Beta-galactosidase-positive cells were identified in all embryonic tissues including inner cell mass, epiblast, mesoderm, endoderm and definitive ectoderm. In contrast, embryos infected with a MoMuLV-based vector expressing the lacZ gene driven off the viral LTR showed beta-galactosidase-positive cells only in mesoderm and definitive ectoderm. We conclude that permissiveness to transcriptional activity of the LTR is acquired immediately upon differentiation of epiblast during gastrulation of the mouse embryo.

Noninfectious ARK mouse embryo cell lines in which each cell has the capacity to be activated to produce infectious murine leukemia virus

Virology ◽  
1971 ◽  
Vol 46 (3) ◽  
pp. 866-876 ◽  
Author(s):  
Wallace P. Rowe ◽  
Janet W. Hartley ◽  
Marilyn R. Lander ◽  
Wendell E. Pugh ◽  
Natalie Teich
Keyword(s):  
Cell Lines ◽  
Mouse Embryo ◽  
Murine Leukemia Virus ◽  
Leukemia Virus ◽  
Embryo Cell ◽  
Mouse Embryo Cell ◽  
Murine Leukemia
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