Zinc halide complexes of imidazolidine-2-thione and its derivatives: X-ray structures, solid state, solution NMR and antimicrobial activity studies

2007 ◽  
Vol 60 (4) ◽  
pp. 369-377 ◽  
Author(s):  
Mohammed Fettouhi ◽  
Mohamed I. M. Wazeer ◽  
Anvarhusein A. Isab
Keyword(s):  
Antimicrobial Activity ◽  
Solid State ◽  
State Solution ◽  
Solution Nmr ◽  
X Ray ◽  
Halide Complexes

Search of structure and ligands exchange for palladium(II) complexes with N-allylimidazole; X-ray and solid-state/solution NMR studies

2006 ◽  
Vol 691 (5) ◽  
pp. 869-878 ◽  
Author(s):  
Krystyna Kurdziel ◽  
Sebastian Olejniczak ◽  
Andrzej Okruszek ◽  
Tadeusz Głowiak ◽  
Rafał Kruszyński ◽  
...  
Keyword(s):  
Solid State ◽  
State Solution ◽  
Solution Nmr ◽  
Nmr Studies ◽  
X Ray ◽  
Ligands Exchange

scholarly journals Organofluorine chemistry: Difluoromethylene motifs spaced 1,3 to each other imparts facial polarity to a cyclohexane ring

2016 ◽  
Vol 12 ◽  
pp. 2823-2827 ◽  
Author(s):  
Mathew J Jones ◽  
Ricardo Callejo ◽  
Alexandra M Z Slawin ◽  
Michael Bühl ◽  
David O'Hagan
Keyword(s):  
Solid State ◽  
Design Strategy ◽  
Chair Conformation ◽  
Axial Orientation ◽  
Solution Nmr ◽  
Cyclohexane Ring ◽  
X Ray

2,2-Dimethyl-5-phenyl-1,1,3,3-tetrafluororocyclohexane has been prepared and characterised as an example of a facially polarised cyclohexane containing 1,3 related CF2 groups. The dipolar nature of the ring arises from the axial orientation of two of the C–F bonds pointing in the same direction, and set by the chair conformation of the cyclohexane. This electrostatic profile is revealed experimentally both in the solid-state (X-ray) packing of the rings and by solution (NMR) in different solvents. A computationally derived electrostatic profile of this compound is consistent with a more electronegative and a more electropositive face of the cyclohexane ring. This placing of CF2 groups 1,3 to each other in a cyclohexane ring is introduced as a new design strategy which could be applicable to the preparation of polar hydrophobic cyclohexane motifs.

scholarly journals The Radiostability of Meropenem Trihydrate in Solid State

Molecules ◽  
2018 ◽  
Vol 23 (11) ◽  
pp. 2738 ◽  
Author(s):  
Karolina Kilińska ◽  
Judyta Cielecka-Piontek ◽  
Robert Skibiński ◽  
Daria Szymanowska ◽  
Andrzej Miklaszewski ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Solid State ◽  
Physical Stability ◽  
Chemical Degradation ◽  
Beam Radiation ◽  
Promising Alternative ◽  
X Ray ◽  
Lactam Ring ◽  
Ft Ir ◽  
Hydroxyethyl Group

The influence of ionising radiation on the physicochemical properties of meropenem trihydrate in solid state was studied for doses of e-beam radiation: 25 kGy and 400 kGy. In the first part of our studies, we evaluated the possibility of applying radiosterilization to obtain sterile meropenem. No changes for meropenem irradiated with a dose of 25 kGy, the dose required to attain sterility, was confirmed in the results of spectroscopic (FT-IR), thermal (DSC, TGA) and X-ray powder diffraction (XRPD) studies. The radiation dose of 25 kGy produces no more than about 1500 ppm of radical defects. The chromatographic studies of irradiated meropenem in solutions did not show any chemical degradation. Moreover, the antimicrobial activity of meropenem irradiated with the dose of 25 kGy was unchanged. Based on the received results, we can conclude that radiostelization is a promising, alternative method for obtaining sterile meropenem. In the second part of the research, meropenem was exposed to e-beam radiation at the 400 kGy dose rate. It was confirmed, that reducing of antimicrobial activity could be connected with the degradation of β-lactam ring and changes in the trans-hydroxyethyl group. Apart from chemical changes, changes in the physical stability of irradiated meropenem (400 kGy) was also observed.

Solid state and solution NMR, X-ray and antimicrobial studies of 1:1 and 2:1 complexes of silver(I) cyanide with alkanediamine ligands

2007 ◽  
Vol 360 (12) ◽  
pp. 3719-3726 ◽  
Author(s):  
Anvarhusein A. Isab ◽  
Mohamed I.M. Wazeer ◽  
Mohammed Fettouhi ◽  
Bassem A. Al-Maythalony ◽  
Abdul Rahman Al-Arfaj ◽  
...  
Keyword(s):  
Solid State ◽  
Solution Nmr ◽  
X Ray ◽  
Antimicrobial Studies

ChemInform Abstract: Synthesis, Solid-State (X-Ray) and Solution (NMR) Studies of the Hydridocarbido Carbonyl Cluster Anion (Re7H2C(CO)21)-.

ChemInform ◽  
1990 ◽  
Vol 21 (37) ◽  
Author(s):  
T. BERINGHELLI ◽  
G. D'ALFONSO ◽  
G. CIANI ◽  
A. SIRONI ◽  
H. MOLINARI
Keyword(s):  
Solid State ◽  
Cluster Anion ◽  
Solution Nmr ◽  
Carbonyl Cluster ◽  
Nmr Studies ◽  
X Ray

Behavior of beryllium halides and triflate in acetonitrile solutions

2020 ◽  
Vol 75 (11) ◽  
pp. 939-949
Author(s):  
Nils Spang ◽  
Matthias Müller ◽  
William Augustinov ◽  
Magnus R. Buchner
Keyword(s):  
Raman Spectroscopy ◽  
Solid State ◽  
Dominant Species ◽  
State Structure ◽  
X Ray Diffraction ◽  
X Ray ◽  
Halide Complexes ◽  
Acetonitrile Solutions ◽  
Dinuclear Compounds ◽  
Ir And Raman

AbstractThe solution behavior of beryllium halides and triflate in acetonitrile was studied by NMR, IR and Raman spectroscopy. Thereby mononuclear units [(MeCN)2BeX2] (X = Cl, Br, I, OTf) were identified as dominant species in these solutions. The solid state structure of [(MeCN)2Be(OTf)2] has been determined by X-ray diffraction. If only one equivalent of MeCN is used the dinuclear compounds [(MeCN)BeX2]2 (X = Cl, Br, I) are formed. Partial halide and triflate dissociation into the monomeric complexes as well as the formation of hetero-halide complexes [(MeCN)2BeClBr], [(MeCN)2BeClI] and [(MeCN)2BeBrI] was observed.

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