Effect of Spore-bearing Lactic Acid-forming Bacteria ( Bacillus coagulans SANK 70258) Administration on the Intestinal Environment, Defecation Frequency, Fecal Characteristics and Dermal Characteristics in Humans and Rats

2002 ◽  
Vol 14 (1) ◽  
pp. 4-13 ◽  
Author(s):  
Katsutoshi Ara ◽  
Shinichi Meguro ◽  
Tadasi Hase ◽  
Ichirou Tokimitsu ◽  
Kazuya Otsuji ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Bacillus Coagulans ◽  
Intestinal Environment ◽  
Defecation Frequency

Effects of heat-killed Lactobacillus kunkeei YB38 on human intestinal environment and bowel movement: a pilot study

2016 ◽  
Vol 7 (3) ◽  
pp. 337-344 ◽  
Author(s):  
T. Asama ◽  
Y. Kimura ◽  
T. Kono ◽  
T. Tatefuji ◽  
K. Hashimoto ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Lactic Acid Bacteria ◽  
Intestinal Microbiota ◽  
Bowel Movement ◽  
Baseline Period ◽  
Intestinal Environment ◽  
Human Intestinal Microbiota ◽  
Defecation Frequency ◽  
Bacteroides Fragilis Group ◽  
Lactobacillus Kunkeei

It is well known that lactic acid bacteria supplementation is beneficial for intestinal conditions such as microbiota; however, the effects of killed-lactic acid bacteria on intestinal conditions are largely unclear. This study aimed to evaluate the effect of heat-killed Lactobacillus kunkeei YB38 (YB38) at a dose of approximately 10 mg/day on human intestinal environment and bowel movement. This single-blind study enrolled 29 female subjects with a low defecation frequency who consumed heat-killed YB38 at four increasing dosage levels: 0 (placebo), 2, 10, and 50 mg. Each dose was consumed daily for two weeks, with a two-week baseline period preceding the dosing-period and a two-week washout period ending the study. Observed levels of Bacteroides fragilis group significantly decreased with intake of heat-killed YB38 at ≥10 mg/day compared with levels during placebo intake (P<0.01). Faecal pH significantly decreased with 10 and 50 mg/day intake (P<0.01 and 0.05, respectively). Acetic acid levels tended to increase in faeces at the 50 mg/day dose (P<0.1). Bowel movement tended to increase in all heat-killed YB38 intake periods (P<0.1). In conclusion, heat-killed YB38 altered human intestinal microbiota at doses of ≥10 mg/day and tended to increase bowel movement at ≥2 mg/day. This is the first study to show the intestinal microbiota-altering effect of L. kunkeei and to report the bowel movement-improving effect of heat-killed lactic acid bacteria.

scholarly journals Draft Genome Sequence of Bacillus coagulans NL01, a Wonderful l-Lactic Acid Producer

2015 ◽  
Vol 3 (3) ◽  
Author(s):  
Zhaojuan Zheng ◽  
Ting Jiang ◽  
Xi Lin ◽  
Jie Zhou ◽  
Jia Ouyang
Keyword(s):  
Lactic Acid ◽  
Genome Sequence ◽  
Draft Genome ◽  
Bacillus Coagulans ◽  
Draft Genome Sequence

scholarly journals A Process Study of Lactic Acid Production from Phragmites australis Straw by a Thermophilic Bacillus coagulans Strain under Non-Sterilized Conditions

Processes ◽  
2018 ◽  
Vol 6 (10) ◽  
pp. 175 ◽  
Author(s):  
Yuming Zhang ◽  
Mengran Li ◽  
Tian Nie ◽  
Zhihua Ni
Keyword(s):  
Lactic Acid ◽  
Phragmites Australis ◽  
Lactic Acid Production ◽  
Scale Up ◽  
Bacillus Coagulans ◽  
Dilute Acid Pretreatment ◽  
Integrated Process ◽  
Dilute Acid ◽  
Acid Pretreatment ◽  
Process Study

Phragmites australis straw (PAS) is an abundant and renewable wetland lignocellulose. Bacillus coagulans IPE22 is a robust thermophilic strain with pentose-utilizing capability and excellent resistance to growth inhibitors. This work is focused on the process study of lactic acid (LA) production from P. australis lignocellulose which has not been attempted previously. By virtue of thermophilic feature of strain IPE22, two fermentation processes (i.e., separated process and integrated process), were developed and compared under non-sterilized conditions. The integrated process combined dilute-acid pretreatment, hemicellulosic hydrolysates fermentation, and cellulose utilization. Sugars derived from hemicellulosic hydrolysates and cellulose enzymatic hydrolysis were efficiently fermented to LA in a single vessel. Using the integrated process, 41.06 g LA was produced from 100 g dry PAS. The established integrated process results in great savings in terms of time and labor, and the fermentation process under non-sterilized conditions is easy to scale up for economical production of lactic acid from PAS.

scholarly journals Effect of Bifidobacterium longum BB536 Administration on the Intestinal Environment, Defecation Frequency and Fecal Characteristics of Human Volunteers

1997 ◽  
Vol 16 (2) ◽  
pp. 53-58 ◽  
Author(s):  
Tomohiro OGATA ◽  
Teiichi NAKAMURA ◽  
Katsue ANJITSU ◽  
Tomoko YAESHIMA ◽  
Sachiko TAKAHASHI ◽  
...  
Keyword(s):  
Bifidobacterium Longum ◽  
Intestinal Environment ◽  
Human Volunteers ◽  
Defecation Frequency

scholarly journals High-throughput screening of high lactic acid-producing Bacillus coagulans by droplet microfluidic based flow cytometry with fluorescence activated cell sorting

RSC Advances ◽  
2019 ◽  
Vol 9 (8) ◽  
pp. 4507-4513 ◽  
Author(s):  
Xu-Dong Zhu ◽  
Xiang Shi ◽  
Shu-Wen Wang ◽  
Ju Chu ◽  
Wei-Hong Zhu ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
Lactic Acid ◽  
High Throughput ◽  
Cell Sorting ◽  
High Throughput Screening ◽  
Bacillus Coagulans ◽  
Screening System ◽  
Fluorescence Activated Cell Sorting ◽  
Microfluidic Sorting

A high-throughput screening system based on droplet microfluidic sorting was developed and employed for screening of high lactic acid-producing Bacillus coagulans.

scholarly journals Kaskadennutzung von Lignocellulose: LX-Verfahren trifft auf B. coagulans

BIOspektrum ◽  
2020 ◽  
Vol 26 (7) ◽  
pp. 803-805
Author(s):  
Linda Schroedter ◽  
Friedrich Streffer ◽  
Katrin Streffer ◽  
Peter Unger ◽  
Joachim Venus
Keyword(s):  
Lactic Acid ◽  
Energy Saving ◽  
Optical Purity ◽  
Bacillus Coagulans ◽  
The Novel ◽  
Corn Straw

AbstractInvestigating alternatives for petrobased substrates, lignocellulose is an interesting yet complex feedstock that offers various possibilities for the design of new and sustainable chemical routes. The novel energy-saving LX-pretreatment was combined with thermophilic Bacillus coagulans. By this, corn straw was used in an innovative cascade obtaining biogas, lignin as well as polymerisable L-(+)-lactic acid of over 99 percents optical purity.

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