The Claremont serial killer and the production of class-based suburbia in serial killer mythology

Continuum ◽  
2022 ◽  
pp. 1-20
Author(s):  
Laura Glitsos ◽  
Jessica Taylor
Keyword(s):  
Serial Killer

Who Was the First Serial Killer?

PsycCRITIQUES ◽  
2006 ◽  
Vol 51 (14) ◽  
Author(s):  
Maureen O'Sullivan
Keyword(s):  
Serial Killer

O SERIAL KILLER FRENTE A LEGISLAÇÃO BRASILEIRA: ESTUDOCOMPARADO NA BUSCA DA IDEIAL MEDIDA DE INTERNAÇÃO JUDICIAL

2019 ◽  
Vol 8 (1) ◽  
pp. 23
Author(s):  
Jonathan Cardoso Régis ◽  
Larrisa Da Silva
Keyword(s):  
Serial Killer

<p>O presente artigo tem como base um estudo comparado para o estudo Serial Killer frente a legislação Brasileira. Apesar da ausência de estudo dentro do ordenamento jurídico Brasileiro, indivíduos acometidos por esse tipo de característica se fazem presentes, e muitas vezes sem o atendimento correto. Tendo o aprisionamento incorreto desse individuo esse pode potencializar a violência e o número de vítimas. Diante da ausência de normal penal especifica para o comportamento, os mesmos passam ao tratamento convencional, não cessando sua periculosidade, e não podendo reintegrar novamente a sociedade.</p>

scholarly journals Designed improvement to T-cell immunotherapy by multidimensional single cell profiling

2021 ◽  
Vol 9 (3) ◽  
pp. e001877
Author(s):  
Irfan N Bandey ◽  
Jay R T Adolacion ◽  
Gabrielle Romain ◽  
Melisa Martinez Paniagua ◽  
Xingyue An ◽  
...  
Keyword(s):  
T Cells ◽  
T Cell ◽  
Single Cell ◽  
Adoptive Cell Therapy ◽  
Population Heterogeneity ◽  
Serial Killer ◽  
Car T Cells ◽  
Car T ◽  
Single Cell Profiling ◽  
Killer T Cells

BackgroundAdoptive cell therapy based on the infusion of chimeric antigen receptor (CAR) T cells has shown remarkable efficacy for the treatment of hematologic malignancies. The primary mechanism of action of these infused T cells is the direct killing of tumor cells expressing the cognate antigen. However, understanding why only some T cells are capable of killing, and identifying mechanisms that can improve killing has remained elusive.MethodsTo identify molecular and cellular mechanisms that can improve T-cell killing, we utilized integrated high-throughput single-cell functional profiling by microscopy, followed by robotic retrieval and transcriptional profiling.ResultsWith the aid of mathematical modeling we demonstrate that non-killer CAR T cells comprise a heterogeneous population that arise from failure in each of the discrete steps leading to the killing. Differential transcriptional single-cell profiling of killers and non-killers identified CD137 as an inducible costimulatory molecule upregulated on killer T cells. Our single-cell profiling results directly demonstrate that inducible CD137 is feature of killer (and serial killer) T cells and this marks a different subset compared with the CD107apos (degranulating) subset of CAR T cells. Ligation of the induced CD137 with CD137 ligand (CD137L) leads to younger CD19 CAR T cells with sustained killing and lower exhaustion. We genetically modified CAR T cells to co-express CD137L, in trans, and this lead to a profound improvement in anti-tumor efficacy in leukemia and refractory ovarian cancer models in mice.ConclusionsBroadly, our results illustrate that while non-killer T cells are reflective of population heterogeneity, integrated single-cell profiling can enable identification of mechanisms that can enhance the function/proliferation of killer T cells leading to direct anti-tumor benefit.

scholarly journals From unusual suspect to serial killer: Cyanotoxins boosted by climate change may jeopardize megafauna

2021 ◽  
Vol 2 (2) ◽  
pp. 100092 ◽  
Author(s):  
Haijun Wang ◽  
Chi Xu ◽  
Ying Liu ◽  
Erik Jeppesen ◽  
Jens-Christian Svenning ◽  
...  
Keyword(s):  
Climate Change ◽  
Serial Killer

scholarly journals No One is Born a Serial Killer!

2013 ◽  
Vol 81 ◽  
pp. 324-328 ◽  
Author(s):  
Ilie Magdalena Ioana
Keyword(s):  
Serial Killer

Specter of a serial killer

2007 ◽  
Vol 13 (1) ◽  
pp. 23-23
Author(s):  
Lyle R Petersen
Keyword(s):  
Serial Killer

Let the Right One In

2011 ◽  
Author(s):  
Anne Billson
Keyword(s):  
Social Realism ◽  
Serial Killer ◽  
Modern World ◽  
Housing Estate ◽  
Love Story ◽  
The World ◽  
The Right

These days it takes a very special vampire movie to stand out. Like Twilight, the Swedish film Let the Right One In is a love story between a human and a vampire but there the resemblance ends. Let the Right One In is not a romantic fantasy but combines the supernatural with social realism. Set on a housing estate in the suburbs of Stockholm in the early 1980s, it's the story of Oskar, a lonely, bullied child, who makes friends with Eli, the girl in the next apartment. 'Oskar, I'm not a girl,' she tells him and she's not kidding. They forge a relationship which is oddly innocent yet disturbing, two outsiders against the rest of the world. But one of these outsiders is, effectively, a serial killer. While Let the Right One In is startlingly original, it nevertheless couldn't have existed without the near century of vampire cinema that preceded it. This book looks at how it has drawn from, and wrung new twists on, such classics as Nosferatu (1922), how vampire cinema has already flirted with social realism in films like Near Dark (1987) and how vampire mythology adapts itself to the modern world.

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