Pancreatitis-associated protein as an early marker of asparaginase-associated pancreatitis

2021 ◽  
pp. 1-5
Author(s):  
Julius Lukes ◽  
Benjamin O. Wolthers ◽  
Raheel Altaf Raja ◽  
Karolina Uhrinova ◽  
Karolina Skvarova Kramarzova ◽  
...  
Gut ◽  
1996 ◽  
Vol 39 (5) ◽  
pp. 675-678 ◽  
Author(s):  
E Kemppainen ◽  
J Sand ◽  
P Puolakkainen ◽  
S Laine ◽  
J Hedstrom ◽  
...  

2005 ◽  
Vol 173 (4S) ◽  
pp. 165-165
Author(s):  
Paolo Gontero ◽  
Elisabetta Omodeo-Zorini ◽  
Paola Cacciotti ◽  
Filippo Sogni ◽  
Ervin Kocjancic ◽  
...  

2021 ◽  
Vol 27 (S1) ◽  
pp. 1138-1139
Author(s):  
Francisco Capani ◽  
Lucas Udovin ◽  
Tamara Kobiec ◽  
Camila Menendez ◽  
Toro-Urrego Nicolas ◽  
...  

Pituitary ◽  
2021 ◽  
Author(s):  
Paul Eugène Constanthin ◽  
Nathalie Isidor ◽  
Sophie de Seigneux ◽  
Shahan Momjian

Abstract Purpose The syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is a well-known complication of transsphenoidal pituitary surgery, related to inappropriate secretion of arginine vasopressin (AVP). Its diagnosis is based on hyponatremia, with a peak of occurrence around day 7 after surgery and, to date, no early marker has been reported. In particular, copeptin levels are not predictive of hyponatremia in this case. Oxytocin (OXT) is secreted into the peripheral blood by axon terminals adjacent to those of AVP neurons in the posterior pituitary. Besides its role in childbirth and lactation, recent evidences suggested a role for OXT in sodium balance. The contribution of this hormone in the dysnatremias observed after pituitary surgery has however never been investigated. Methods We analyzed the urinary output of OXT in patients subjected to transsphenoidal pituitary surgery. Results While OXT excretion remained stable in patients who presented a normonatremic postoperative course, patients who were later diagnosed with SIADH-related hyponatremia presented with a significantly increased urinary secretion of OXT 4 days after surgery. Conclusion Taken together, these results show for the first time that urinary OXT output remains normally stable after transsphenoidal pituitary surgery. OXT excretion however becomes abnormally high on or around 4 days after surgery in patients later developing hyponatremia, suggesting that this abnormal dynamics of OXT secretion might serve as an early marker for transsphenoidal surgery-related hyponatremia attributed to SIADH.


2008 ◽  
Vol 9 (4) ◽  
pp. 343-351 ◽  
Author(s):  
Michele Terzaghi ◽  
Elena Sinforiani ◽  
Chiara Zucchella ◽  
Elena Zambrelli ◽  
Chiara Pasotti ◽  
...  

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