The Maturing of Hormesis as a Credible Dose-Response Model
2003 ◽
Vol 1
(3)
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pp. 154014203902499
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Hormesis is a dose-response phenomenon that has received little recognition, credibility and acceptance as evidenced by its absence from major toxicological/risk assessment texts, governmental regulatory dose-response modeling for risk assessment, and non-visibility in major professional toxicological society national meetings. This paper traces the historical evolution of the hormetic dose-response hypothesis, why this model is not only credible but also more common than the widely accepted threshold model in direct comparative evaluation, and how the toxicological community made a critical error in rejecting hormesis, a rejection sustained over 70 years.
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2008 ◽
Vol 327
(2)
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pp. 288-299
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Keyword(s):
2004 ◽
Vol 39
(3)
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pp. 334-347
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Keyword(s):
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