Non-invasive electrical stimulation of oropharyngeal muscles in obstructive sleep apnoea

Author(s):  
Juan Luis RodrÍguez Hermosa ◽  
Myriam Calle ◽  
Ina Guerassimova ◽  
Baldomero FernÁndez ◽  
Víctor Javier Montero ◽  
...  
F1000Research ◽  
2021 ◽  
Vol 10 ◽  
pp. 197
Author(s):  
William D. Moscoso-Barrera ◽  
Luis Mauricio Agudelo‑Otalora ◽  
Angélica María Moreno-Giraldo ◽  
Javier Burguete ◽  
Secundino Fernández ◽  
...  

Obstructive sleep apnoea-hypopnoea syndrome (OSA) is a respiratory disorder characterised by repetitive obstruction of the upper airway, leading to several interruptions during sleep. It is currently one of the main public health problems worldwide and one of the main cardiovascular risk factors in developed and intermediate developing countries, whose populations are increasing in rates of obesity and age. One of the common treatments for OSA is a continuous positive airway pressure (CPAP) device, which pumps air through a hose, reaches a mask that the patient has over his or her nose and travels the airway, keeping the upper airway open during sleep and avoiding episodes of airway collapse. The problem is that CPAP is not accepted by some patients due to a lack of adaptation, so alternative treatments may be needed. For some years, there have been explorations of treatments related to electrical stimulation of the muscles of the upper airway as therapy to reduce the number of episodes of apnoea (measured through the apnoea–hypopnoea index) during the night, strengthening these muscles through stimulation. This is the protocol of the first clinical study of a rehabilitation device for home use that not only provides functional stimulation of the upper-airway dilator muscles but also provides sensory stimulation. This device works by strengthening the dilating muscles of the upper respiratory tract and improving the sensory capacity of the laryngo-pharyngeal tract and is based on existing publications on the effectiveness of functional and somatosensory neurostimulation through neuroplasticity in the recovery of neurological deficits. Trial registration: Clinicaltrials.gov NCT04607343 (29/10/2020)


Thorax ◽  
2016 ◽  
Vol 71 (10) ◽  
pp. 923-931 ◽  
Author(s):  
Martino F Pengo ◽  
Sichang Xiao ◽  
Culadeeban Ratneswaran ◽  
Kate Reed ◽  
Nimish Shah ◽  
...  

2019 ◽  
Vol 29 (7) ◽  
pp. 977-979
Author(s):  
Maria Boutsikou ◽  
Wei Li ◽  
Michael A. Gatzoulis

AbstractIn patients with CHD after Fontan palliation, there is a lack of a pumping chamber in the pulmonary circulation; thus, pulmonary blood flow and cardiac output are sensitive to increased pulmonary vascular resistance; if obstructive sleep apnoea is present, there are legitimate concerns from continuous positive airway pressure ventilation, which may hinder pulmonary blood flow.


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