scholarly journals Pulmonary Infection Due to Mycobacterium marinum in an Immunocompetent Patient

2005 ◽  
Vol 40 (1) ◽  
pp. 206-208 ◽  
Author(s):  
C.-C. Lai ◽  
L.-N. Lee ◽  
Y.-L. Chang ◽  
Y.-C. Lee ◽  
L.-W. Ding ◽  
...  
Keyword(s):  
Pulmonary Infection ◽  
Immunocompetent Patient ◽  
Mycobacterium Marinum

scholarly journals Pulmonary Cryptococcosis in the Immunocompetent Patient—Many Questions, Some Answers

2016 ◽  
Vol 3 (3) ◽  
Author(s):  
John F. Fisher ◽  
Paula A. Valencia-Rey ◽  
William B. Davis
Keyword(s):  
Pulmonary Infection ◽  
Case Reports ◽  
Severe Disease ◽  
Case Series ◽  
Immunocompetent Patient ◽  
Pulmonary Cryptococcosis ◽  
Polysaccharide Antigen ◽  
Prospective Data ◽  
Radiographic Findings ◽  
Oral Fluconazole

Abstract Background.  There are no prospective data regarding the management of pulmonary cryptococcosis in the immunocompetent patient. Clinical guidelines recommend oral fluconazole for patients with mild to moderate symptoms and amphotericin B plus flucytosine followed by fluconazole for severe disease. It is unclear whether patients who have histological evidence of Cryptococcus neoformans but negative cultures will even respond to drug treatment. We evaluated and managed a patient whose presentation and course raised important questions regarding the significance of negative cultures, antifungal choices, duration of therapy, and resolution of clinical, serologic, and radiographic findings. Methods.  In addition to our experience, to answer these questions we reviewed available case reports and case series regarding immunocompetent patients with pulmonary cryptococcosis for the last 55 years using the following definitions: Definite - Clinical and/or radiographic findings of pulmonary infection and respiratory tract isolation of C. neoformans without other suspected etiologies; Probable - Clinical and radiographic findings of pulmonary infection, histopathologic evidence of C. neoformans, and negative fungal cultures with or without a positive cryptococcal polysaccharide antigen. Results.  Pulmonary cryptococcosis resolves in most patients with or without specific antifungal therapy. Clinical, radiographic, and serologic resolution is slow and may take years. Conclusions.  Persistently positive antigen titers are most common in untreated patients and may remain strongly positive despite complete or partial resolution of disease. Respiratory fungal cultures are often negative and may indicate nonviable organisms.

scholarly journals Cryptococcal Meningitis in an Immunocompetent Patient with a Ventriculo-Pleural Shunt

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Raynieri Fernandez ◽  
Jose Henao ◽  
Catherine Creticos
Keyword(s):  
Cryptococcal Meningitis ◽  
Pulmonary Infection ◽  
Organ Transplant ◽  
Immunocompetent Patient ◽  
Solid Organ ◽  
Transplant Recipients ◽  
Cerebrospinal Fluid Analysis ◽  
Fluid Analysis ◽  
Cell Immunity ◽  
Solid Organ Transplant Recipients

Cryptococcal meningitis is the most common form of infection caused by Cryptococcus yeast species, followed by pulmonary infection. It is an opportunistic infection seen in patients with impaired cell immunity, most frequently in HIV patients and solid organ transplant recipients; however, it can occur in patients with no apparent immunodeficiency. We describe the case of Cryptococcus neoformans meningitis in an immunocompetent patient with aseptic cerebrospinal fluid analysis which highlights the heterogeneity of this disease.

Mycobaterium fortuitum disseminated infection in an immunocompetent patient without predisposing factors

2020 ◽  
Vol 13 (9) ◽  
pp. e235842
Author(s):  
Stephanie d'Incau ◽  
Maria-Isabel Vargas ◽  
Alexandra Calmy ◽  
Jean-Paul Janssens
Keyword(s):  
Risk Factors ◽  
Pulmonary Infection ◽  
Skin Lesions ◽  
Immunocompetent Patient ◽  
Definitive Diagnosis ◽  
Optimal Treatment ◽  
Molecular Techniques ◽  
Surgical Removal ◽  
Mycobacterium Fortuitum ◽  
Direct Inoculation

Most Mycobacterium fortuitum infections described involve direct inoculation through skin lesions. We describe the case of a patient without risk factors who presented with an intracranial mass and a pulmonary infection with M. fortuitum. As M. fortuitum are rarely pathogens, there is little knowledge about the optimal treatment and outcome of such infections: what is the best mode of administration, what is the best therapy duration and is surgery always required are some of the unanswered questions. In our patient, surgical removal of the mass associated with a 1-year antimycobacterial therapy led to a full recovery. Even though M. fortuitum was rapidly identified in sputum, it was initially considered non-pathogenic and the definitive diagnosis required almost 6 weeks of investigations. New molecular techniques will probably lead to more identifications of M. fortuitum in the next few years and a better knowledge of their possible pathogenicity and optimal treatment.

Pulmonary Infection due to Mycobacterium gordonae in an Adolescent Immunocompetent Patient

Respiration ◽  
1997 ◽  
Vol 64 (4) ◽  
pp. 300-303 ◽  
Author(s):  
B. Resch ◽  
E. Eber ◽  
A. Beitzke ◽  
C. Bauer ◽  
M. Zach
Keyword(s):  
Pulmonary Infection ◽  
Immunocompetent Patient

scholarly journals Case report: Medullary cryptococcosis in a immunocompetent patient

2021 ◽  
Author(s):  
Joao Paste Silva ◽  
Catarina Secundino ◽  
Tiago Timotio ◽  
Aurea Angelica Paste
Keyword(s):  
Case Report ◽  
Pulmonary Infection ◽  
Opportunistic Infections ◽  
Spinal Tuberculosis ◽  
Memory Loss ◽  
Immunocompetent Patient ◽  
Unusual Manifestation ◽  
Meningeal Irritation ◽  
Cranial Neuropathies ◽  
One Year

Context: Cryptococcosis is an important fungal infection that, after AIDS development globally, became more common, being an important cause of opportunistic infections. The pathogen normally gets in through the lungs, causes pulmonary infection and then spreads to another systems, particularly the nervous system in most cases. Along the clinical manifestation there was headache, fever, cranial neuropathies, altered mentation, lethargy, memory loss, and signals of meningeal irritation. Case-Report: A 48-year-old male patient with a one-year story of paraparesis in both legs, associated with pain, paresthesia, and progressive worsening to complete walking incapability, seeks medical consultation. Cerebrospinal fluid was turbid appearance, yellow colored, presence of RBC (1.239 cel/mm³) and leukocytes (149 cel/mm³ - 5% neutrophils, 91% lymphocytes and 4% monocytes), glucose of 23 mg/dL, chlorine of 96 mmol/L, and Cryptococcus neoformans was isolated. Immunosuppressive disease wasn´t found. In MRI, there were nodular images in the intradural and extradural sites through T11-T12 levels, compressing the spinal cord. Local biopsy revealed chronic granulomatous inflammatory process, consistent with the cryptococcosis suspect. Conclusions: The case represents an unusual manifestation of cryptococcosis, with an uncommon topography and profile, once it´s manifestation medullary and in a healthy individual is rare. The main differential diagnosis was spinal tuberculosis, an also rare disease yet with similar symptoms and relevant local epidemiology. To reach the diagnosis, laboratory study was necessary. The treatment was the same of cryptococcosis in general.

A novel cause of invasive pulmonary infection in an immunocompetent patient: Aspergillus candidus

2005 ◽  
Vol 51 (4) ◽  
pp. e195-e197 ◽  
Author(s):  
S.C.C. Ribeiro ◽  
A.N.C. Santana ◽  
G.H. Arriagada ◽  
J.E.C. Martins ◽  
T.Y. Takagaki
Keyword(s):  
Pulmonary Infection ◽  
Immunocompetent Patient ◽  
Aspergillus Candidus

A case of Mycobacterium nonchromogenicum pulmonary infection showing multiple nodular shadows in an immunocompetent patient

2006 ◽  
Vol 54 (4) ◽  
pp. 311-314 ◽  
Author(s):  
Toyomitsu Sawai ◽  
Yuichi Inoue ◽  
Seiji Doi ◽  
Koichi Izumikawa ◽  
Hideaki Ohno ◽  
...  
Keyword(s):  
Pulmonary Infection ◽  
Immunocompetent Patient

scholarly journals A Case of Hypercalcemia in an Immunocompetent Patient with Disseminated Mycobacterium marinum Infection with a Rain Barrel as the Most Likely Primary Source

2021 ◽  
Author(s):  
Wendy Uijtendaal ◽  
Rima Yohanna ◽  
Folkert Visser ◽  
Paul Ossenkoppele ◽  
Dorine Hess ◽  
...  
Keyword(s):  
Renal Failure ◽  
Rare Case ◽  
Primary Source ◽  
Immunocompetent Patient ◽  
Human Infection ◽  
Mycobacterium Marinum ◽  
Contaminated Water ◽  
Immunocompromised Patients

Infection with Mycobacterium marinum is common in fish, and so human infection usually arises from contact with contaminated water or fish. A solitary papulonodular lesion on a finger or hand is the typical presentation. Disseminated infections are rare and mostly seen in immunocompromised patients. We present a rare case of disseminated M. marinum infection presenting with polyarthritis, tenosynovitis, dactylitis, and (sub)cutaneous and intramuscular lesions in an immunocompetent patient. This case was complicated by hypercalcemia, renal failure and eventually death. A contaminated rain barrel was most likely the primary source of the infection.

Sign in / Sign up

Export Citation Format

Share Document