scholarly journals Effect of Different Level of Zeolite and Perlite on The Physiological Performance of Awassi Lambs

2021 ◽  
Vol 923 (1) ◽  
pp. 012039
Author(s):  
Asaad Fadhel Tarsh ◽  
Ahmed Jawad Al-Yasseri
Keyword(s):  
Blood Parameters ◽  
Low Density Lipoproteins ◽  
The Other ◽  
Physiological Traits ◽  
High Density Lipoproteins ◽  
Control Group ◽  
Low Density ◽  
The Third ◽  
Awassi Sheep ◽  
Awassi Lambs

Abstract A total of 24 male Awassi lamb aged (4-6) months were used, to determine the effect of different level of zeolite and perlite on the physiological traits of Awassi sheep. Results show that te use of zeolite led to the presence of high significant differences at the level (P ≤ 0.05) of the studied values between the experimental groups and according to the weeks of the study, as the values varied between different weeks in the characteristics of the biochemical blood parameters and values, which are (both cholesterol values, the values of high-density lipoproteins, low-density lipoproteins, and fats). All treatments of zeolite and perylite and their mixture outperformed the control group, while the fourth treatment T4 outperformed the other treatments, followed by the third treatment T3 over the studied treatments T2 and T1.

The therapeutic effect of some drugs and vegetable juices on the lipid profiles in male rabbits induced atherosclerosis.

2019 ◽  
Vol 9 (o3) ◽  
Author(s):  
Sawsan Taha Ahmed al-Haddad ◽  
Zaid Mohammed Mubarak Almahdawi ◽  
Munife S. Ahmed Al-janabi
Keyword(s):  
Green Tea ◽  
Density Lipoprotein ◽  
Lemon Juice ◽  
Low Density Lipoproteins ◽  
High Density ◽  
High Density Lipoproteins ◽  
Control Group ◽  
Low Density ◽  
Very Low Density Lipoproteins ◽  
Group 5

This study was designed to test the therapeutic efficacy of some hypotensive drugs and vegetable drinks on some biochemical indicators in male rabbits, where atherosclerosis was developed using 1% cholesterol with food. This study was conducted in June until the end of July 2017 in the Pharmacology Department/ General Company for Pharmaceutical Industry in Samarra. In the study, 50 local rabbits were randomly distributed by 10 groups each containing 5 animals. The first group considered as the control group. The second group is the control group treated with 1% cholesterol with the food, the third group treated with cholesterol (1% and captopril 0.71 mg), group 4 (cholesterol 1% with atenolol 0.71 mg / kg), group 5 (cholesterol 1%, amlodipine 0.07 mg / kg) , group 6 treated with cholesterol 1% and aldomet (0.57 mg / kg), group 7 (cholesterol 1% and furosemide at 3.5 mg / kg), group 8 (cholesterol 1% with garlic syrup 2 ml), group 9 treatment cholesterol 1% and lemon juice), and group 10 Treatment with (1% cholesterol and green tea syrup 2 ml). The results of the study showed a significant increase (P≤0.01)) at the level of each of cholesterol triple and triglycerides, proteins and low density lipoproteins, very low density lipoproteins, also led to obtain a significant decrease in the level of high-density lipoproteins (HDL) in the treatment group with cholesterol 1% compared to control group. At the time of the treatment of anti- pressure drugs: Captopril, Atenolol, Amlodipine ,Aldomet, and Furosmide , there were no significant differences in the cholesterol level of all pharmacological groups. Moral differences were not found in LDL-C and there was a significant decrease (P≤0.01) of the level of triglycerides, proteins and very low density lipoproteins, and there was a significant increase in the level of high-density lipoproteins HDL-C, while treatment with plant juices, there was a significant decrease (P≤0.01) in the level of total cholesterol and triglycerides and LDL, and VLDL, high-density lipoprotein (HDL-C) increased when treated with garlic, lemon and green tea. We conclude pressure drugs of any kind can cure atherosclerosis or prevent high fat, unlike its counterparts OF plants, which have shown a significant effect on controlling lipid profile and reducing their effects and future risks on the heart.

scholarly journals STUDY OF THE EFFECT OF CHITOSAN EXTRACTED FROM THE MUSHROOM ON THE EXPERIMENTALLY INDUCED HYPERLIPIDEMIA IN MALE RABBITS

2021 ◽  
Vol 13 (2) ◽  
pp. 79-88
Author(s):  
إبراهيم خلف حميد الدليمي ◽  
◽  
أسماء هاشم شاكر ◽  
فهد خلف ياسين ◽  
◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Research Study ◽  
Low Density Lipoproteins ◽  
High Density Lipoproteins ◽  
Control Group ◽  
Low Density ◽  
Very Low Density Lipoproteins ◽  
Glucose Levels ◽  
Significant Difference ◽  
Therapeutic Evaluation

The present study aimed to identify the therapeutic evaluation of chitosan extracted from the fungus cushroom and pure chitosan on glucose and lipid profile in the blood of 35 male rabbits with hyperlipidemia induced experimentally by cholesterol. The tests included estimation of glucose levels, total cholesterol, triglycerides, high-density lipoproteins, low-density lipoproteins, and very low-density lipoproteins. hyperlipidemia was induced in the male rabbits used in the study which was administered orally with cholesterol 150mg/kg body weight for a week. rabbits were divided into seven groups: control, cholesterol, pure chitosan, mushroom chitosan, cholesterol and pure chitosan, cholesterol and mushroom chitosan and cholesterol and simvastatin. The results of the study showed, the hyperlipidemia induced experimentally resulted a significant increase (P<0.05) in TC, TG, LDL, and VLDL, while no significant difference in HDL compared with control group, on the otherwise the glucose level significantly increase than control. Also, groups of animals treatment with pure chitosan and mushroom chitosan showed a significant decrease (P<0.05) in glucose, TC, TG, LDL, and VLDL, and no significant difference in HDL compared with control group. While, the groups showed treatment with cholesterol and pure chitosan, cholesterol and mushroom chitosan, cholesterol and simvastatin a significant decrease (P<0.05) in glucose, TC, TG, LDL, and VLDL, and a significant increase (P<0.05) in HDL compared with the cholesterol group. The research study revealed that chitosan extracted from mushroom can control the levels of fat concentrations and their complications, in addition to its important role in biochemical variables, and treatment of most disease cases, especially cardiovascular disease.

scholarly journals Study of the correlations between serum iron and Hepcidin with some biochemical variables in hyperlipidemia of elderly males and females in Salah Al Deen Province

2020 ◽  
Vol 25 (2) ◽  
pp. 9
Author(s):  
Khalida Khalil Abdullah1 ◽  
Saleh Mohammed Rahim2
Keyword(s):  
Low Density Lipoproteins ◽  
High Density ◽  
High Density Lipoproteins ◽  
Control Group ◽  
Low Density ◽  
Very Low Density Lipoproteins ◽  
Correlation Relationship ◽  
Biochemical Variables ◽  
Elderly Males ◽  
Males And Females

The present research was designed to investigate the role of the relationship between Iron and hepcidin hormon with some biochemical variables in patients with hyperlipidemia in both males and females elderly in Salah al-Din governorate. The study included 40 individuals distributed into two groups. The first group was the control group, which included 20 human males and females and the second group included 20 patients (10 males and 10 females) whose ages ranged between (60-79) years. Blood was collected to estimate the hepcidine hormone, iron, cholesterol, triglycerides, high-density lipoproteins, low-density lipoproteins, and very low-density lipoproteins. The results showed a significant increase in (P≥ 0.05) in the concentration of iron and hepcidin hormone, cholesterol, triglycerides, low-density lipoproteins and very low-density lipoproteins while showed a significant decrease in (P≥ 0.05) in the concentration high-density lipoproteins in patients Males and females hyperlipidemia compared to the control group. The results also indicated a direct correlation relationship between iron and hepcidine hormone and studied variables cholesterol, triglycerides, low-density lipoproteins and very low-density lipoproteins in patients compared to the control group. It is concluded through the results that iron and the hepcidin hormon may have an important role in the development of cardiovascular diseases in hypertensive patients in elderly both males and females.            http://dx.doi.org/10.25130/tjps.25.2020.023

scholarly journals Parametry metabolizma i gemostazapri endogennom giperkortitsizme s narusheniemuglevodnogo obmena

2011 ◽  
Vol 8 (3) ◽  
pp. 26-29
Author(s):  
G G Petrik ◽  
S A Pavlishchuk
Keyword(s):  
Diabetes Mellitus ◽  
Lipid Metabolism ◽  
Adrenal Gland ◽  
Low Density Lipoproteins ◽  
High Density Lipoproteins ◽  
Control Group ◽  
Low Density ◽  
Average Volume ◽  
Chronic Hyperglycemia ◽  
The Impact

The aim of the study was to determine peculiarities of protein and lipid metabolism as well as platelet-coagulation hemostasis depending on the pathogenesis of the endogenous hypercortisolism and assessment of the impact of chronic hyperglycemia on studied parameters. Materials and methods. The study included 19 patients with pituitary microadenomas with median age of 45,0 (41; 49) years and 9 patients with nodular adrenal gland hyperplasia aged 49,5 (42; 57) years, 14 of whom had diabetes mellitus. Results. Biochemical and coagulation parameters in patients with endogenous hyperpercortisolism regardless of ethiology Cushing`s syndrome differed from the control group in increased concentration of total cholesterol, high-density lipoproteins, low-density lipoproteins, alpha2-globulins and decreased gamma globulins, as well as in increased average volume of platelets and enhanced aggregation properties. Carbohydrate metabolism disorders were not characterized by significant differences in metabolic parameters and platelet hemostasis, but were accompanied by the reduction of APTT.

Selective uptake of cholesteryl esters from various classes of lipoproteins by HepG2 cells

1999 ◽  
Vol 77 (2) ◽  
pp. 157-163 ◽  
Author(s):  
Louise Brissette ◽  
Marie-Claude Charest ◽  
Louise Falstrault ◽  
Julie Lafond ◽  
David Rhainds ◽  
...  
Keyword(s):  
Total Lipid ◽  
Hepg2 Cells ◽  
Ldl Receptor ◽  
Inverse Correlation ◽  
Low Density Lipoproteins ◽  
High Density Lipoproteins ◽  
Low Density ◽  
Cholesteryl Esters ◽  
Very Low Density Lipoproteins ◽  
Selective Uptake

Selective uptake of cholesteryl esters (CE) from lipoproteins by cells has been extensively studied with high density lipoproteins (HDL). It is only recently that such a mechanism has been attributed to intermediate and low density lipoproteins (IDL and LDL). Here, we compare the association of proteins and CE from very low density lipoproteins (VLDL), IDL, LDL and HDL3 to HepG2 cells. These lipoproteins were either labelled in proteins with 125I or in CE with 3H-cholesteryl oleate. We show that, at any lipoprotein concentration, protein association to the cells is significantly smaller for IDL, LDL, and HDL3 than CE association, but not for VLDL. At a concentration of 20 µg lipoprotein/mL, these associations reveal CE-selective uptake in the order of 2-, 4-, and 11-fold for IDL, LDL, and HDL3, respectively. These studies reveal that LDL and HDL3 are good selective donors of CE to HepG2 cells, while IDL is a poor donor and VLDL is not a donor. A significant inverse correlation (r2 = 0.973) was found between the total lipid/protein ratios of the four classes of lipoproteins and the extent of CE-selective uptake by HepG2 cells. The fate of 3H-CE of the two best CE donors (LDL and HDL3) was followed in HepG2 cells after 3 h of incubation. Cells were shown to hydrolyze approximately 25% of the 3H-CE of both lipoproteins. However, when the cells were treated with 100 µM of chloroquine, a lysosomotropic agent, 85 and 40% of 3H-CE hydrolysis was lost for LDL and HDL3, respectively. The fate of LDL and HDL3-CE in HepG2 cells deficient in LDL-receptor was found to be the same, indicating that the portion of CE hydrolysis sensitive to chloroquine is not significantly linked to LDL-receptor activity. Thus, in HepG2 cells, the magnitude of CE-selective uptake is inversely correlated with the total lipid/protein ratios of the lipoproteins and CE-selective uptake from the two best CE donors (LDL and HDL3) appears to follow different pathways.Key words: lipoprotein, receptor, HepG2 cell, selective uptake, lipid, cholesterol, binding.

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