Metastasis of colorectal carcinoma in the testis: first sign of peritoneal disease

Abstract Metastases of colorectal carcinoma (CRC) in the testis are very rare and indicate an advanced stage of disease. In this case report, we present a patient with adenocarcinoma in the sigmoid colon with metastasis in the right testis. Testicular metastasis of CRC is mostly diagnosed late because of their low incidence rate. Patients with CRC and testicular metastasis have a poor prognosis. In this case, the patient turned out to have peritoneal metastasis and one should be aware that testicular metastasis could be the first sign of widespread disease.

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Management of Pleural Brucellosis: Case Report

Infectious Diseases Research and Treatment ◽

10.4137/idrt.s2235 ◽

2009 ◽

Vol 2 ◽

pp. IDRT.S2235 ◽

Cited By ~ 1

Author(s):

Adel Alothman ◽

Salih Bin Salih ◽

Salwa Alothman ◽

Ghassan Al Johani

Keyword(s):

Case Report ◽

Pleural Effusion ◽

Incidence Rate ◽

Pleural Fluid ◽

Middle Eastern ◽

Developed Countries ◽

History Of ◽

Chest X Ray ◽

Low Incidence ◽

The Right

Background Brucellosis is a zoonotic disease, with low incidence rate in developed countries, however the incidence rate in Middle Eastern countries remains high. Chest symptoms in brucellosis cases account for about 15% of the cases, but dealing with respiratory system involvement is rare particularly pleural involvement. Case Report We report a case of a 60-year-old Saudi woman who was admitted with two months history of fever, productive cough anorexia and weight loss, contact with sheep. She was ill looking, underweight and febrile while she was on treatment. Examination of the chest showed signs of pleural effusion on the right side with right infrascapular crepitations. Chest X-ray: showed pleural effusion and right LL infiltrates. CT chest: showed right loculated, pleural effusion. Pleural fluid examination showed exudative changes, on culture of pleural fluid, Brucella species grew. AFB in pleural fluid was negative. She was treated with Streptomycin, Doxycyclin and Ciprofloxacin. She improved within one week of treatment and was discharged, after 14 days on antibrucella therapy. Discussion Pulmonary brucellosis is reported in medical literature occasionally but only few reports are available about pleural brucellosis. The challenge with pleural brucellosis and the association of loculated abscesses lies in therapy. Due to lack of previous information with such cases, we suggest that a period of more than six weeks is needed to treat this condition. We recommend that pleural brucellosis needs to be treated with at least two therapeutic agents for nine weeks.

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Acquired retinoschisis and vitreous hemorrhage as unusual findings in choroideremia: Case report

European Journal of Ophthalmology ◽

10.1177/1120672120946576 ◽

2020 ◽

pp. 112067212094657

Author(s):

Dario Pasquale Mucciolo ◽

Vittoria Murro ◽

Dario Giorgio ◽

Andrea Sodi ◽

Ilaria Passerini ◽

...

Keyword(s):

Case Report ◽

Retinal Pigment Epithelium ◽

Pigment Epithelium ◽

Retinal Pigment ◽

Vitreous Hemorrhage ◽

Advanced Stage ◽

Vascular Abnormalities ◽

Diagnostic Difficulties ◽

The Right

Purpose: To report a case of choroideremia characterized by peripheral retinoschisis with vascular abnormalities and vitreous hemorrhage. Observations: A 58-year-old man affected by advanced-stage choroideremia was diagnosed with peripheral retinoschisis in both eyes. Vitreous hemorrhage was present in the right eye with a peculiar clot-like lesion at the periphery. At the 1-year follow-up, the vitreous hemorrhage had reabsorbed and the vascular clot-like lesion in the periphery had almost completely disappeared. Conclusion and importance: We have reported fundoscopic and OCT features of peripheral-acquired retinoschisis with vascular abnormalities in a patient with choroideremia. OCT examination is extremely useful in clinical evaluation of the peripheral retinal alterations in these cases, where the absence of the retinal pigment epithelium and the choriocapillaris pose many diagnostic difficulties.

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Colorectal Carcinoma in Childhood and Adolescence: A Clinicopathologic Review

Journal of Clinical Oncology ◽

10.1200/jco.2007.12.6102 ◽

2007 ◽

Vol 25 (36) ◽

pp. 5808-5814 ◽

Cited By ~ 95

Author(s):

D. Ashley Hill ◽

Wayne L. Furman ◽

Catherine A. Billups ◽

Shannon E. Riedley ◽

Alvida M. Cain ◽

...

Keyword(s):

Colorectal Carcinoma ◽

Signs And Symptoms ◽

Distant Metastases ◽

Adult Patients ◽

Childhood And Adolescence ◽

Colon Polyps ◽

Advanced Stage ◽

Mucinous Histology ◽

Pathologic Features ◽

The Right

Purpose Pediatric colorectal carcinoma (CRC) is rare, but the available data suggest that it is more likely than adult CRC to be advanced at presentation and to have a poor outcome. We sought to better characterize pediatric CRC. Patients and Methods We reviewed the clinical and pathologic features, prognostic factors, and outcome of CRC in 77 children and adolescents (ages 7 to 19 years) referred to St Jude Children's Research Hospital between 1964 and 2003. Results At presentation, 76 patients had one or more signs or symptoms of CRC (abdominal pain, altered bowel habits, weight loss, anemia). Tumors were evenly distributed between the right and left colon; 62% were mucinous adenocarcinoma. At presentation, 86% of patients had advanced-stage disease; more than half had distant metastases. Overall outcome was poor. Advanced stage and mucinous histology were significant predictors of adverse outcome. Stage-specific survival at 10 years was 67% ± 27% (stage 1), 38% ± 15% (stage 2), 28% ± 11% (stage III), and 7% ± 4% (stage 4). Although no patient had a diagnosis of polyposis syndrome before diagnosis of CRC, 17 (22%) had colon polyps and eight (including two who previously underwent pelvic radiotherapy) had multiple polyps. Conclusion Initial signs and symptoms of CRC are similar in pediatric and adult patients. The strikingly higher frequency of mucinous histology suggests that the biology of CRC differs in pediatric and adult patients and may contribute to poor outcomes. Children should be included in prospective clinical trials for CRC.

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Light chain systemic amyloidosis manifested as liver failure complicated with fatal spontaneous splenic rupture: A case report

10.22541/au.162346339.94478454/v1 ◽

2021 ◽

Author(s):

Li Duo ◽

Zhao Yingren ◽

Chen Hongmei

Keyword(s):

Case Report ◽

Liver Failure ◽

Incidence Rate ◽

Light Chain ◽

Poor Prognosis ◽

Splenic Rupture ◽

Systemic Amyloidosis ◽

Spontaneous Splenic Rupture ◽

Treatment Methods

Light chain systemic amyloidosis has low clinical incidence rate and poor prognosis. Relevant diagnosis depends on the biopsy results, and many patients were not confirmed until autopsy. Once amyloidosis is suspected, it is necessary to communicate with their families on the risks for treatment methods and prognosis.

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Sarcomatous Carcinoma of the Orbit: A Case Report and Review of the Literature

Case Reports in Ophthalmology ◽

10.1159/000431282 ◽

2015 ◽

Vol 6 (2) ◽

pp. 180-185

Author(s):

Ninan Mathew ◽

Mathen Mathew ◽

Jon Farrah

Keyword(s):

Case Report ◽

Poor Prognosis ◽

Advanced Disease ◽

English Literature ◽

Treatment Options ◽

Malignant Cells ◽

Review Of The Literature ◽

Immunological Markers ◽

Rare Tumours ◽

The Right

Sarcomatous carcinomas (SCs) are rare tumours that contain malignant cells with epithelial and mesenchymal characteristics. SC rarely presents in the head and neck, and occurs even less often in the orbit. Only 8 cases of SCs located in the orbit or affecting the globe function have been described in the English literature. Here, we report a case of SC affecting the right orbit. SC is associated with a poor prognosis and advanced disease at presentation. Diagnosis is difficult, as histology often fails to definitively identify SC, necessitating a wide panel of molecular/immunological markers. Treatment options are generally aggressive but risky, and frequently yield poor results. Due to the rarity of SC, there has been little focus on the development of improved treatment options.

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Carcinosarcoma del cuello uterino: reporte de un caso y revisión de la literatura

Revista de Obstetricia y Ginecología de Venezuela ◽

10.51288/00810314 ◽

2021 ◽

Vol 81 (03) ◽

pp. 297-302

Author(s):

Fátima Palomo Rodríguez ◽

Marta Romero Matas ◽

Álvaro Gutiérrez Domingo ◽

Manuel Pantoja Garrido

Keyword(s):

Side Effects ◽

Uterine Cervix ◽

Poor Prognosis ◽

Advanced Stage ◽

Cervical Mass ◽

Published Evidence ◽

Specific Protocol ◽

Low Incidence ◽

Cervical Tumors ◽

Radio Chemotherapy

Cervical carcinosarcomas are extremely rare, accounting for less than 0.5% of cervical tumors. Due to its low incidence there is no specific protocol of action, which is associated with a poor prognosis. It is frequently diagnosed in postmenopausal women and in advanced stage, with large tumors with vaginal and parametrial metastases. Surgery is considered the treatment of choice, requiring in some cases adjuvant radio-chemotherapy. The prognosis will depend fundamentally on the stage at the time of diagnosis. Since there is little published evidence on this type of tumors we see the need for the publication of cases and reviews of the literature in this regard, to develop unified protocols for the management of this rare pathology. We present the case of a 51-yearold woman who consulted for postmenopausal metrorrhagia, observing a cervical mass with vaginal involvement, corresponding to a carcinosarcoma of the cervix; receiving treatment with radio-chemotherapy, with few side effects and good response. Keywords: Carcinosarcoma, uterine cervix, chemotherapy, radiotherapy, surgery.

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Testicular metastasis from colorectal carcinoma: A case report

10.5348/z15-2017-6-cr-3 ◽

2020 ◽

Keyword(s):

Case Report ◽

Colorectal Carcinoma ◽

Testicular Metastasis

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Isolated Liver Metastasis of Sacrococcygeal Chordoma: Case Report and Review of the Literature

Case Reports in Oncological Medicine ◽

10.1155/2014/826584 ◽

2014 ◽

Vol 2014 ◽

pp. 1-3 ◽

Cited By ~ 1

Author(s):

Murat Akyol ◽

Umut Varol ◽

Ibrahim Yildiz ◽

Ibrahim Vedat Bayoglu ◽

Yasar Yildiz ◽

...

Keyword(s):

Case Report ◽

Liver Metastasis ◽

Poor Prognosis ◽

Systemic Treatment ◽

The Body ◽

Advanced Stage ◽

Review Of The Literature ◽

Anatomic Site ◽

Rare Presentation ◽

Isolated Liver

Chordomas are rare neoplasms arising from notochordal remnants and may develop anywhere in the body while the most common anatomic site is the sacrococcygeal area. The most effective treatment of chordoma is surgery. Chordomas rarely metastasize to lung, bone, soft tissue, liver, lymph nodes, and skin. However, there is currently no standard systemic treatment for advanced stage chordoma. Here, we reported a rare presentation of chordoma patient with liver only metastases and poor prognosis.

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Renal medullary carcinoma and its association with sickle cell trait: a case report and literature review

Current Oncology ◽

10.3747/co.27.5043 ◽

2020 ◽

Vol 27 (1) ◽

Cited By ~ 1

Author(s):

P. Holland ◽

J. Merrimen ◽

C. Pringle ◽

L. A. Wood

Keyword(s):

Case Report ◽

Literature Review ◽

Sickle Cell ◽

Poor Prognosis ◽

Sickle Cell Trait ◽

Medullary Carcinoma ◽

Advanced Stage ◽

Review Of The Literature ◽

Renal Medullary Carcinoma

Renal medullary carcinoma (rmc) is a rare and aggressive renal malignancy that usually presents at an advanced stage, has a poor prognosis, and is associated with sickle cell trait. We present a case of rmc including radiologic and pathology findings, treatment, and outcome. A review of the literature is also presented, with an emphasis on the association of rmc with sickle cell trait, which was an unknown diagnosis in our patient preoperatively.

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