HIV-1 and Tat Neuropathogenesis and Therapeutic Targets

2011 ◽  
pp. 289-304
Author(s):  
Wenxue Li ◽  
Guanhan Li ◽  
Joseph Steiner ◽  
Avindra Nath
Keyword(s):  
Therapeutic Targets ◽  
Hiv 1

Novel HIV-1 Therapeutic Targets:

2021 ◽  
pp. 294-327
Author(s):  
CATHERINE ULICH ◽  
RICHARD B. GAYNOR
Keyword(s):  
Therapeutic Targets ◽  
Hiv 1

HIV-1 integrase and RNase H activities as therapeutic targets

2002 ◽  
Vol 6 (4) ◽  
pp. 433-446 ◽  
Author(s):  
ML Andréola ◽  
V Richard De Soultrait ◽  
M Fournier ◽  
V Parissi ◽  
C Desjobert ◽  
...  
Keyword(s):  
Therapeutic Targets ◽  
Rnase H ◽  
Hiv 1

Ubiquitin ligases as therapeutic targets in HIV-1 infection

2008 ◽  
Vol 12 (2) ◽  
pp. 131-143 ◽  
Author(s):  
Jörg Votteler ◽  
Ulrich Schubert
Keyword(s):  
Therapeutic Targets ◽  
Ubiquitin Ligases ◽  
Hiv 1

Ultrastructural observations of human monocytes infected with HIV-1

1991 ◽  
Vol 49 ◽  
pp. 108-109
Author(s):  
James K. Koehler ◽  
Steven G. Reed ◽  
Joao S. Silva
Keyword(s):  
Gradient Centrifugation ◽  
Virus Production ◽  
Human Monocyte ◽  
Red Cross ◽  
Human Monocytes ◽  
Blood Monocytes ◽  
Hiv Replication ◽  
Electron Microscopic ◽  
Ultrastructural Studies ◽  
Hiv 1

As part of a larger study involving the co-infection of human monocyte cultures with HIV and protozoan parasites, electron microscopic observations were made on the course of HIV replication and infection in these cells. Although several ultrastructural studies of the cytopathology associated with HIV infection have appeared, few studies have shown the details of virus production in “normal,” human monocytes/macrophages, one of the natural targets of the virus, and suspected of being a locus of quiescent virus during its long latent period. In this report, we detail some of the interactions of developing virons with the membranes and organelles of the monocyte host.Peripheral blood monocytes were prepared from buffy coats (Portland Red Cross) by Percoll gradient centrifugation, followed by adherence to cover slips. 90-95% pure monocytes were cultured in RPMI with 5% non-activated human AB serum for four days and infected with 100 TCID50/ml of HIV-1 for four hours, washed and incubated in fresh medium for 14 days.

Astrocytic adhesion molecules are increased in HIV-1-associated cognitive/motor complex

1997 ◽  
Vol 23 (3) ◽  
pp. 83-92 ◽  
Author(s):  
D. Seilhean ◽  
A. Dzia-Lepfoundzou ◽  
V. Sazdovitch ◽  
B. Cannella ◽  
C. S. Raine ◽  
...  
Keyword(s):  
Adhesion Molecules ◽  
Motor Complex ◽  
Hiv 1

Ability of caregivers to read delayed hypersensitivity skin tests in children exposed to and infected by HIV*1

2000 ◽  
Vol 14 (2) ◽  
pp. 50-55
Author(s):  
FORTHEPEDIATRICPULMONARYANDCA ◽  
H COHEN ◽  
X CHEN ◽  
S SUNKLE ◽  
L DAVIS ◽  
...  
Keyword(s):  
Delayed Hypersensitivity ◽  
Skin Tests ◽  
Hypersensitivity Skin ◽  
Hiv 1
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