scholarly journals Influence of Early Combined Antiretroviral Therapy on Maintenance of Long-Term Serological and Cellular Immune Response to Varicella Vaccination in Perinatally Human Immunodeficiency Virus-Infected Children and Adolescents

2016 ◽  
Vol 3 (suppl_1) ◽  
Author(s):  
German Contreras ◽  
James R. Murphy ◽  
Gloria P. Heresi
2015 ◽  
Vol 2 (4) ◽  
Author(s):  
Sabine Kinloch-de Loes ◽  
Lucy Dorrell ◽  
Hongbing Yang ◽  
Gareth A. D. Hardy ◽  
Sabine Yerly ◽  
...  

Abstract Combination antiretroviral therapy during primary human immunodeficiency virus-1 infection may enable long-term drug-free virological control in rare individuals. We describe a female who maintained aviremia and a normal CD4+/CD8+ T cell ratio for 10 years after stopping therapy, despite a persistent viral reservoir. Cellular immune responses may have contributed to this outcome.


Vaccines ◽  
2019 ◽  
Vol 7 (3) ◽  
pp. 110 ◽  
Author(s):  
Overduin ◽  
van Dongen ◽  
Visser

The effectiveness of rabies vaccines is conventionally determined by serological testing. In addition to this assessment of humoral immunity, cellular immunity could help assess effectiveness and protection through a broad range of parameters. Therefore, this study aimed to systematically review all literature on the kinetics and composition of the cellular immune response to rabies vaccination in humans. A total of 1360 studies were identified in an extensive literature search. Twenty studies were selected for inclusion. In a primary response, plasma cells are detectable from day 7 to day 14, peaking at day 10. Memory B-cells appear from day 10 up to at least day 28. After revaccination, natural killer (NK) cells are the first detectable cellular parameters. Further research is required to assess cellular parameters in relation to long-term (serological) immunity. This review was registered in the International Prospective Register of Systematic Reviews (PROSPERO) under registration number CRD42019134416.


2017 ◽  
Vol 67 (2) ◽  
pp. 123-129
Author(s):  
Wipawee Nittayananta ◽  
Aree Kanjanaprapas ◽  
Pratanporn Arirachakaran ◽  
Kanokporn Pangsomboon ◽  
Hutcha Sriplung

2013 ◽  
Vol 167 (6) ◽  
pp. 520 ◽  
Author(s):  
Steven E. Lipshultz ◽  
Paige L. Williams ◽  
James D. Wilkinson ◽  
Erin C. Leister ◽  
Russell B. Van Dyke ◽  
...  

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