scholarly journals Psychological Inflexibility as a Predictor of Sexual Functioning Among Women with Vulvovaginal Pain: A Prospective Investigation

Pain Medicine ◽  
2020 ◽  
Vol 21 (12) ◽  
pp. 3596-3602
Author(s):  
Pernilla Maathz ◽  
Ida K Flink ◽  
Linnea Engman ◽  
Johanna Ekdahl

Abstract Objective Persistent vulvovaginal pain affects many women and often has adverse effects on sexual functioning. Psychological inflexibility related to pain is associated with distress and functional disability across different types of chronic pain conditions, but little is known about the role of psychological inflexibility in vulvovaginal pain. The present study examines psychological inflexibility related to pain as a predictor of sexual functioning over time among women with vulvovaginal pain. Methods Questionnaires including measures of psychological inflexibility, pain severity, and sexual functioning were administered to female university students at two points in time. One hundred thirty women with vulvovaginal pain responded to the questionnaire at baseline and at follow-up after 10 months. A multiple regression model was used to explore psychological inflexibility and pain severity as predictors of sexual functioning at follow-up. Results Higher levels of psychological inflexibility and more severe pain at baseline were associated with poorer sexual functioning 10 months later. In analysis adjusting for baseline levels of sexual functioning, psychological inflexibility was the only significant predictor of sexual functioning at follow-up. Conclusions The findings provide preliminary evidence that psychological inflexibility is associated with sexual adjustment over time among women with vulvovaginal pain and point to the relevance of further examinations of the psychological inflexibility model in the context of vulvovaginal pain.

2020 ◽  
Vol 44 (2) ◽  
pp. 257-270 ◽  
Author(s):  
Deepika Rao ◽  
Martha Maurer ◽  
Jodi Meyer ◽  
Jiaying Zhang ◽  
Olayinka O. Shiyanbola

Objectives: In this study, we conducted a longitudinal evaluation of changes in medication adherence and the role of psychosocial and interpersonal factors in these changes among Blacks with type 2 diabetes mellitus (T2DM), and determined barriers and facilitators of T2DM medication adherence. Methods: We used an explanatory sequential mixed methods design for a sample of 287 black adult patients with T2DM in Wisconsin. Two surveys quantitatively evaluated changes in medication adherence, psychosocial factors, and interpersonal factors over time. We conducted 10 semi-structured qualitative interviews to explore participants' perceptions of these changes. Data integration of the quantitative and qualitative findings elucidated barriers and facilitators of medication adherence. Results: Increased adherence was significantly correlated with less concerns about medicines (r = -0.31), higher self-efficacy (r = 0.47), lesser depressive symptoms (r = -0.26), and lesser negative illness perceptions (r = -0.26) at both baseline and follow-up. Patient perceptions of adherence changes included adherence motivators, social support, and complex medication regimens. Integration showed that barriers and facilitators both existed in individuals who had an increase or a decrease in adherence over time. Conclusions: Specific beliefs of Blacks towards T2DM medications must be addressed to improve their adherence. Interventions must be tailored using interpersonal factors.


2010 ◽  
Vol 13 (3) ◽  
pp. 335-340 ◽  
Author(s):  
Michael C. Ain ◽  
Madeel A. Abdullah ◽  
Beverlie L. Ting ◽  
Richard L. Skolasky ◽  
Emily Streyer Carlisle ◽  
...  

Object The aim of this study was to assess the natural history of pain associated with spinal stenosis in individuals with achondroplasia and to characterize pain patterns and associated functional and psychological effects. Methods The authors measured pain severity, spatial distribution of pain, functional disability, psychological distress, physical symptoms other than pain, and healthcare utilization in 181 individuals with achondroplasia. They also assessed low back and/or lower extremity pain at the initial visit and 1-year follow-up via self-rated patient questionnaires, calculated composite scores from responses via component analyses, and used repeated measures linear regression analyses for score changes (significance, p ≤ 0.05). Results At the follow-up, back pain severity was unchanged. Patients reported significant progression of pain toward involvement of the lower extremities and significant increases in lower extremity pain severity overall. There were also significant increases in healthcare utilization overall. Compared with patients with back pain only, those with back pain and proximal or distal leg pain had higher self-rated pain severity; higher functional disability; and more bowel and bladder dysfunction symptoms, sleep disturbances, extremity numbness, and psychological distress. Conclusions Individuals with achondroplasia and symptomatic spinal stenosis often experience back pain, which may progress to lower extremity pain and debilitating consequences. A more thorough understanding of the progression of spatial pain characteristics and pain severity may aid clinical decision making regarding the optimal timing for intervention.


2013 ◽  
Vol 25 (7) ◽  
pp. 1115-1123 ◽  
Author(s):  
Melissa Mathews ◽  
Erin Abner ◽  
Allison Caban-Holt ◽  
Richard Kryscio ◽  
Frederick Schmitt

ABSTRACTBackground:The Consortium to Establish a Registry for Alzheimer's Disease (CERAD) set of tests is frequently used for tracking cognition longitudinally in both clinical and research settings. Repeated cognitive assessments are an important component in measuring such changes; however, practice effects and attrition bias may obscure significant clinical change over time. The current study sought to examine the presence and magnitude of practice effects and the role of attrition bias in a sample of cognitively normal older men enrolled in a prevention trial.Method:Participants were grouped according to whether they completed five years of follow-up (n = 182) or less (n = 126). Practice effects were examined in these participants as a whole (n = 308) and by group.Results:Findings indicate that moderate practice effects exist in both groups on the CERAD T-score and that attrition bias likely does not play a contributing role in improved scores over time.Conclusion:The current study provides additional evidence and support for previous findings that repeated cognitive assessment results in rising test scores in longitudinally collected data and demonstrates that these findings are unlikely to be due to attrition.


2020 ◽  
Vol 8 (3) ◽  
pp. 450-463 ◽  
Author(s):  
Karey L. O’Hara ◽  
Austin M. Grinberg ◽  
Allison M. Tackman ◽  
Matthias R. Mehl ◽  
David A. Sbarra

In this study, we examined the association between naturalistically observed in-person contact with an ex-partner and separation-related psychological distress (SRPD). One hundred twenty-two recently separated adults were assessed using the Electronically Activated Recorder on three occasions across 5 months. The association between in-person contact with an ex-partner, as a between-person variable, and concurrent SRPD was not reliably different from zero, nor was the time-varying effect of in-person contact. However, more frequent in-person contact with an ex-partner predicted higher SRPD 2 months later, above and beyond the variance accounted for by concurrent in-person contact, demographic, relationship, and attachment factors. Follow-up analyses showed that this effect was present only for people without children; a 1 SD increase in in-person contact offset and slowed the predicted decline in SRPD over 2 months by 112%. In our discussion, we emphasize new ways to think about the role of in-person contact in shaping adults’ psychological adjustment to separation over time.


2019 ◽  
Author(s):  
Karey O'Hara ◽  
Austin Grinberg ◽  
Allison Mary Tackman ◽  
Matthias R. Mehl ◽  
David Sbarra

This study examined the association between naturalistically-observed in-person contact with one’s ex-partner and separation-related psychological distress (SRPD). 122 recently separated adults were assessed using the Electronically Activated Recorder (Mehl, 2017) on three occasions across five months. The association between in-person contact with one’s expartner, as a between-person variable, and concurrent SRPD was not reliably different from zero, nor was the time-varying effect of in-person contact. However, more frequent in-person contact with one’s ex-partner predicted higher SRPD two months later, above and beyond the variance accounted for by oncurrent in-person contact, demographic, relationship, and attachment factors. Follow-up analyses yielded that this effect was only present for people without children; a one standard deviation increase in in-person contact offset and slowed the predicted decline in SRPD over two months by 112%. Our discussion emphasizes new ways to think about the role of interpersonal contact in shaping adults’ psychological adjustment to separation over time.


Author(s):  
Leah M. Schumacher ◽  
J. Graham Thomas ◽  
Rena R. Wing ◽  
Hollie A. Raynor ◽  
Ryan E. Rhodes ◽  
...  

Background: Exercising at a consistent versus variable time of day cross-sectionally relates to greater moderate to vigorous physical activity (MVPA) among weight loss maintainers. This study evaluated the relationships between exercise timing and both MVPA levels and habit strength, as well as stability in exercise timing, over 1 year among maintainers in the National Weight Control Registry. Methods: Participants (n = 709) completed questionnaires assessing exercise timing, MVPA, and exercise automaticity (a measure of habit) at baseline and 1-year follow-up. At each assessment, participants were labeled temporally consistent exercisers if >50% of their exercise sessions per week occurred in one time window: early morning, late morning, afternoon, or evening. Participants exercising consistently during the same window at both assessments were labeled as having stable patterns. Results: Temporally consistent exercise at baseline, regardless of its specific time, related to greater MVPA over time (Ps< .05). Approximately half of temporally consistent exercisers at baseline exhibited stable patterns. Early morning exercise and greater exercise automaticity at baseline predicted stable patterns (Ps< .005). Temporally consistent exercise, especially during the early morning, related to greater automaticity across time (Ps< .01). Conclusions: Consistent exercise timing may help maintainers accrue more MVPA. Consistent early morning exercise was most strongly related to exercise automaticity and routine stability.


2018 ◽  
Vol 16 (1) ◽  
pp. 199-206 ◽  
Author(s):  
Manuel Alcaraz-Ibáñez ◽  
José M. Aguilar-Parra ◽  
Joaquín F. Álvarez-Hernández

2020 ◽  
Vol 46 (6) ◽  
pp. 1608-1618
Author(s):  
Aisling O’Neill ◽  
Eleanor Carey ◽  
Niamh Dooley ◽  
Colm Healy ◽  
Helen Coughlan ◽  
...  

Abstract Abnormal functional connectivity (FC, the temporal synchronization of activation across distinct brain regions) of the default mode (DMN), salience (SN), central executive (CEN), and motor (MN) networks is well established in psychosis. However, little is known about FC in individuals, particularly adolescents, reporting subthreshold psychotic experiences (PE) and their trajectory over time. Thus, the aim of this study was to investigate the FC of these networks in adolescents with PE. In this population-based case-control study, 24 adolescents (mean age = 13.58) meeting the criteria for PE were drawn from a sample of 211 young people recruited and scanned for a neuroimaging study, with a follow-up scan 2 years later (n = 18, mean age = 15.78) and compared to matched controls drawn from the same sample. We compared FC of DMN, SN, CEN, and MN regions between PE and controls using whole-brain FC analyses. At both timepoints, the PE group displayed significant hypoconnectivity compared to controls. At baseline, FC in the PE group was decreased between MN and DMN regions. At follow-up, dysconnectivity in the PE group was more widespread. Over time, controls displayed greater FC changes than the PE group, with FC generally increasing between MN, DMN, and SN regions. Adolescents with PE exhibit hypoconnectivity across several functional networks also found to be hypoconnected in established psychosis. Our findings highlight the potential for studies of adolescents reporting PE to reveal early neural correlates of psychosis and support further investigation of the role of the MN in PE and psychotic disorders.


Author(s):  
Lanfranco D’Elia ◽  
Alfonso Giaquinto ◽  
Roberto Iacone ◽  
Ornella Russo ◽  
Pasquale Strazzullo ◽  
...  

AbstractHigh leptin levels are associated with an unfavorable cardiometabolic risk profile. A number of studies found a positive association between leptin and vascular damage, but to date, no observational study has evaluated a potential predictive role of leptin for arterial stiffening. Therefore, the aim of this study was to estimate the role of leptin in the incidence of arterial stiffening (pulse pressure >60 mmHg) and changes in pulse pressure in an 8-year follow-up of a sample of adult men (The Olivetti Heart Study). The analysis included 460 men without baseline arterial stiffening and antihypertensive treatment at baseline and at follow-up (age: 50.0 years, BMI: 26.5 kg/m2). At the end of the follow-up period, the incidence of arterial stiffening was 8%. Baseline leptin was significantly greater in the group that developed arterial stiffening and was significantly correlated with pulse pressure changes over time (p < 0.05). According to the median plasma leptin distribution of the whole population, the sample was stratified into two groups: one with leptin levels above the median and the other with leptin levels below the median. Those who had baseline leptin levels above the median had a greater risk of developing arterial stiffening (odds ratio: 2.5, p < 0.05) and a greater increase in pulse pressure over time (beta: 2.1, p < 0.05), also after adjustment for confounders. The results of this prospective study indicate a predictive role of circulating leptin levels for vascular damage, independent of body weight and blood pressure.


QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
N Elsheshtawy ◽  
N Fouda ◽  
M Nassif ◽  
N Ahmed

Abstract Objectives To assess the potential role of prolotherapy in treating the most tender points of FM patients as a trial to improve symptoms. Patients and Methods 20 primary FM Patients were injected with 3 cc of 25 % dextrose with 2 cc of 1 % lidocaine and then filled to 6 cc total volume with saline, making dextrose concentration of 12.5%, with 0.5 ml of the solution prepared per point,with a maximum of 6 points/ session. - Follow up visit were required every two weeks for other injections over a course of six weeks (duration of healing cascade). After 6 weeks, patients were assessed using NRS, FIQ VAS , MFI - 20 , SQS and PHQ-9 scales. Results As regard number of tender points, there was a highly Statistically significant P- value (&lt;0.001) between number of tenderpoints (6-16) before injection, which decreased to (5-9) after injection, with a change of 34.17%. As regard whole body average pain, there was a highly Statistically significant difference (&lt;0.001) between NRS before injection(5-10), which decreased to a range of (2-6) after injection, with a change of 39.57%. PHQ-9 scale total score showed a highly Statistically significant difference (P – value&lt;0.001), ranging from (15-22) pre injectionand dropped to (10-18) post injection, with an improvement of 25.37%. Conclusion Prolotherapy may offer great therapeutic advantages for FM patients, as it is well tolerated with minimal or no side effects. Moreover, prolotherapy injection reduces pain intensity and functional disability in daily life activities.


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