scholarly journals Lipidomics Profiles are Related to Preterm Birth and Depressive Symptoms in Pregnant African American Women

2019 ◽  
Vol 33 (S1) ◽  
Author(s):  
Nadia Saadat ◽  
Todd Lydic ◽  
Dawn Misra ◽  
Carmen Giurgescu
Keyword(s):  
African American ◽  
Depressive Symptoms ◽  
Preterm Birth ◽  
African American Women ◽  
American Women

scholarly journals Lipidome Profiles Are Related to Depressive Symptoms and Preterm Birth Among African American Women

2020 ◽  
Vol 22 (3) ◽  
pp. 354-361 ◽  
Author(s):  
Nadia Saadat ◽  
Todd A. Lydic ◽  
Dawn P. Misra ◽  
Rhonda Dailey ◽  
Deborah S. Walker ◽  
...  
Keyword(s):  
African American ◽  
Depressive Symptoms ◽  
Preterm Birth ◽  
African American Women ◽  
Depression Scale ◽  
The United States ◽  
Mass Spectrometry Data ◽  
Orthogonal Projections ◽  
Clear Separation ◽  
American Women

African American women have the highest rate of preterm birth (PTB; <37 completed weeks’ gestation) of any racial and ethnic group in the United States (14.1%). Depressive symptoms (DS) have been linked to PTB risk of African American women. We hypothesized that maternal lipidomic profiles are related to prenatal DS and gestational age at birth among African American women. Women were enrolled at 9–25 weeks’ gestation, completed questionnaires, and provided plasma samples. Lipidomic profiles were determined by “shotgun” Orbitrap high-resolution/accurate mass spectrometry. Data were analyzed using SIMCA P+ software. There was a clear separation in the orthogonal projections to latent structures discriminant analysis score plot between women with Center for Epidemiologic Studies Depression Scale (CES-D) scores ≥23 and women with CES-D scores ≤22. Similarly, a clear separation was observed in the model between PTB and full-term birth. Corresponding S-plot, loading plot, and variable importance in projection plot/list were used to identify the lipids responsible for the groupings. Higher levels of specific triglyceride (TG) species and lower levels of specific phosphatidylcholines (PCs) PC(37:1), PC(41:6), and PC(39:3) were associated with PTB. PC PC(37:1) levels were also lower among women with CES-D scores ≥23, pointing toward a possible connection between DS and PTB. Although overweight pregnant women showed higher levels of TGs, the PTB model showed specific TGs unique to PTB. Lipidomic profiles in pregnant African American women are related to DS, and our data suggest a role for specific TGs and PCs in PTB.

African American Women and Depression: Promoting the Need for Culturally Competent Treatment

2018 ◽  
Author(s):  
Bernice Kennedy ◽  
Chalice Jenkins ◽  
Keyword(s):  
Mental Health ◽  
African American ◽  
Depressive Symptoms ◽  
African American Women ◽  
Mental Health Problems ◽  
American Woman ◽  
Stressful Events ◽  
Mental Illnesses ◽  
Diagnostic Process ◽  
American Women

Abstract Depression is gradually increasing in African American women. These women are experiencing role changes and additional life stressors. Depressed African American women may perceive themselves as being devalued by society with fewer support systems to buffer stressful events. Depressive symptoms may develop into clinical depression and a further decrease in the quality of life for the African American woman. The assumption that all women share similar experiences does not allow for differences to emerge regarding the diagnostic process, measuring tools, and successful treatment strategies for various cultures. The authors developed a Multifaceted Model of Depression in African American Women for improving treatment of African American women with depression and future research needs. Cultural background plays a vital role in how the symptoms of mental illnesses are developed, reported, interpreted, and how women are treated. African Americans who subscribed to the Strong Black Women Archetype (SBWA) are naturally strong, resilient, self-contained, and self-sacrificing. This self-reliance prevents them from reaching out for social support. This, in turn, can contribute to depressive symptoms with negative health outcomes. The African American women are more apt to have less access to routine medical care where early diagnosis and interventions can be done, so their mental health problems (e.g., depression, stress, etc.) are often more developed, complicated, and their social supports more depleted when they do access treatment. When African American women do have access to mental health care, they receive poor quality care compared to Whites.

scholarly journals HIV Prevention Programming for Older African American Women: The Impact of a Faith-Based and Behavioral Science Partnership on Depressive Symptoms

2020 ◽  
Vol 30 (2) ◽  
pp. 287-294
Author(s):  
Megan T. Ebor ◽  
Aurora P. Jackson
Keyword(s):  
African American ◽  
Depressive Symptoms ◽  
Hiv Prevention ◽  
African American Women ◽  
Psychological Wellbeing ◽  
American Women ◽  
Faith Based ◽  
Older African American Women ◽  
The One ◽  
The Impact

Objective: The current study sought to test the effect of an HIV prevention interven­tion on depressive symptoms in a sample of older African American women.Design, Setting and Participants: A pretest-posttest randomized control group design was conducted in a mega-church in Los Angeles with a sample of 62 older African American women, aged ≥50 years, 29 of whom were randomly assigned to the experimental condition and 33 to the comparison/control condition.Measures: A measure of psychological wellbeing (CES-D) was utilized to test the effect of the four-session group interven­tion vs the one-session informational group intervention on change in depressive symp­toms from pretest to posttest. Demographic characteristics included: measures of age in years; relationship and employment statuses (coded 1 for yes, 0 for no); and educational attainment.Results: Participation in the study was as­sociated with a significant improvement in the women’s psychological wellbeing from baseline to time 2; ie, decreased depres­sive symptoms. This change was greater for women in the four-session experimental group than for those in the one-session comparison group, due in part to a margin­ally significant interaction between time and experimental conditions.Conclusions: This study demonstrates the utility of faith-based/behavioral-scientist partnerships in HIV programming. Findings contribute to the evidence on interventions that might reduce depressive symptoms and HIV risk among older African American women. Ethn Dis. 2020;30(2):287-294; doi:10.18865/ed.30.2.287

scholarly journals Discriminatory Experiences and Depressive Symptoms among African American Women: Do Skin Tone and Mastery Matter?

Sex Roles ◽  
2009 ◽  
Vol 62 (1-2) ◽  
pp. 48-59 ◽  
Author(s):  
Verna M. Keith ◽  
Karen D. Lincoln ◽  
Robert Joseph Taylor ◽  
James S. Jackson
Keyword(s):  
African American ◽  
Depressive Symptoms ◽  
African American Women ◽  
Skin Tone ◽  
American Women

scholarly journals Psychosocial and Sociocultural Correlates of Depressive Symptoms Among Diverse African American Women

2012 ◽  
Vol 104 (11-12) ◽  
pp. 493-504 ◽  
Author(s):  
Kisha B. Holden ◽  
Stephanie P. Hall ◽  
Maryam Robinson ◽  
Sharra Triplett ◽  
Dolapo Babalola ◽  
...  
Keyword(s):  
African American ◽  
Depressive Symptoms ◽  
African American Women ◽  
American Women
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