scholarly journals Protein-Sparing Effect in Skeletal Muscle of Growth Hormone Treatment in Critically Ill Patients

2000 ◽  
Vol 231 (4) ◽  
pp. 577-586 ◽  
Author(s):  
Lena Gamrin ◽  
Pia Essén ◽  
Eric Hultman ◽  
Margaret A. McNurlan ◽  
Peter J. Garlick ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Growth Hormone ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Growth Hormone Treatment ◽  
Hormone Treatment ◽  
Protein Sparing ◽  
Sparing Effect

Effects of Caloric Restriction and Growth Hormone Treatment on Insulin‐Related Intermediates in The Skeletal Muscle

2008 ◽  
Vol 22 (S2) ◽  
pp. 116-116
Author(s):  
Khalid A Al‐Regaiey ◽  
Michal M Masternak ◽  
Zhihui Wang ◽  
Jacob Panici ◽  
Andrzej Bartke
Keyword(s):  
Skeletal Muscle ◽  
Growth Hormone ◽  
Caloric Restriction ◽  
Growth Hormone Treatment ◽  
Hormone Treatment

Protein turnover in rat skeletal muscle: effects of hypophysectomy and growth hormone.

1978 ◽  
Vol 234 (1) ◽  
pp. E38 ◽  
Author(s):  
K E Flaim ◽  
J B Li ◽  
L S Jefferson
Keyword(s):  
Skeletal Muscle ◽  
Growth Hormone ◽  
Protein Synthesis ◽  
Protein Turnover ◽  
Gastrocnemius Muscle ◽  
Growth Hormone Treatment ◽  
Hormone Replacement ◽  
Hormone Treatment ◽  
Rat Skeletal Muscle

The role of growth hormone in regulating protein turnover was examined in a perfused preparation of rat skeletal muscle. The perfused muscle maintained in vivo levels of ATP and creatine phosphate and exhibited constant rates of oxygen consumption and protein synthesis. Hypophysectomy reduced the rate of protein synthesis, the concentration of RNA, and the efficiency of protein synthesis in gastrocnemius muscle to 30, 46, and 66 percent of normal, respectively. In vivo treatment of hypophysectomized (hypox) rats with bovine growth hormone (250 microgram/day for 5 days) resulted in small increases in protein synthesis and RNA, whereas synthesis/RNA was returned to near normal. Elevation of ribosomal subunits in psoas muscle indicated an inhibition of peptide-chain initiation in hypox rats that was reversed by in vivo growth hormone treatment. Thus, hypox rats exhibited both a decreased capacity and a decreased efficiency of protein synthesis. Growth hormone replacement primarily increased efficiency of protein synthesis. The rate of protein degradation and the activity of cathepsin D in gastrocnemius muscle were decreased by hypophysectomy. Growth hormone treatment had no significant effect on degradation.

3-27-05 Growth hormone treatment in GH deficient adults: Effects on skeletal muscle and exercise

1997 ◽  
Vol 150 ◽  
pp. S178
Author(s):  
A. Leal-Cerro ◽  
J. Guerra ◽  
D. Segura ◽  
I. Chinchón ◽  
E. Rafel ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Growth Hormone ◽  
Growth Hormone Treatment ◽  
Hormone Treatment

Increased Mortality Associated with Growth Hormone Treatment in Critically Ill Adults

1999 ◽  
Vol 341 (11) ◽  
pp. 785-792 ◽  
Author(s):  
Jukka Takala ◽  
Esko Ruokonen ◽  
Nigel R. Webster ◽  
Michael S. Nielsen ◽  
Durk F. Zandstra ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Critically Ill ◽  
Growth Hormone Treatment ◽  
Hormone Treatment ◽  
Critically Ill Adults ◽  
Ill Adults

Does Growth Hormone Treatment Alter Skeletal Muscle Mitochondrial Respiration in Rats?

2002 ◽  
Vol 58 (6) ◽  
pp. 287-291 ◽  
Author(s):  
C. Peyreigne ◽  
E. Raynaud ◽  
C. Fedou ◽  
C. Prefaut ◽  
J.-F. Brun ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Growth Hormone ◽  
Mitochondrial Respiration ◽  
Growth Hormone Treatment ◽  
Hormone Treatment
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