Evidence of CSF Enhancement in the Spinal Subarachnoid Space After Intravenous Contrast Medium Administration

1979 ◽  
Vol 3 (2) ◽  
pp. 267-269 ◽  
Author(s):  
C. Gene Coin ◽  
Victor J. Keranen ◽  
Menno Pennink ◽  
Wahaj D. Ahmad
2021 ◽  
pp. 1098612X2110385
Author(s):  
Maria Laura Prüllage ◽  
Ilse Schwendenwein ◽  
Eva Eberspächer-Schweda ◽  
Sibylle Kneissl

Objectives The aim of this study was to determine the prevalence of post-contrast acute kidney injury or comparable side effects on kidney function in cats receiving the non-ionic, iodinated agent ioversol and/or paramagnetic agent gadoteric acid. Methods Fifty-two animals were divided into four groups on the basis of contrast medium administration for imaging: ioversol (n = 27), gadoteric acid (n = 12), dual contrast media (n = 4) or control, which received an infusion of isotone intravenous fluids only during anaesthesia (n = 9). Blood and urine samples were obtained three times after contrast administration and compared with values obtained prior to administration of the contrast medium. Creatinine (<1.60 mg/dl), symmetric dimethylarginine (SDMA; ⩽14 μg/dl), urine protein:creatinine ratio (UPC; <0.2) and critical differences for creatinine (<0.3 mg/dl) and SDMA (<5.98 μg/dl) were measured. Results No significant short-term effects on mean creatinine, SDMA and UPC measurements were seen. Borderline proteinuria (UPC, 0.2–0.4) was detected in 11.4% of cases after contrast media administration. A UPC of more than 0.2 in five cases indicated that contrast media may affect kidney function, leading to (transient) proteinuria. Conclusions and relevance This study found no side effect on renal function following the administration of ioversol or gadoteric acid, provided patients were adequately hydrated. However, the clinical relevance of proteinuria in some cats needs to be evaluated in future studies.


Epilepsia ◽  
1996 ◽  
Vol 37 (11) ◽  
pp. 1117-1120 ◽  
Author(s):  
Timothy G. Lukovits ◽  
Camilo E. Fadul ◽  
J. Marc Pipas ◽  
Peter D. Williamson

Radiology ◽  
2013 ◽  
Vol 267 (1) ◽  
pp. 119-128 ◽  
Author(s):  
Jennifer S. McDonald ◽  
Robert J. McDonald ◽  
Jules Comin ◽  
Eric E. Williamson ◽  
Richard W. Katzberg ◽  
...  

2012 ◽  
Vol 125 (1) ◽  
pp. 100.e11-100.e16 ◽  
Author(s):  
Kimberly L. Campbell ◽  
Laryssa M. Hud ◽  
Suzanne Adams ◽  
Jocelyn Andrel ◽  
Samir K. Ballas ◽  
...  

Author(s):  
Hilal Sahin ◽  
Camilla Panico ◽  
Stephan Ursprung ◽  
Vittorio Simeon ◽  
Paolo Chiodini ◽  
...  

Abstract Objective To determine the accuracy of interpretation of a non-contrast MRI protocol in characterizing adnexal masses. Methods and materials Two hundred ninety-one patients (350 adnexal masses) who underwent gynecological MRI at our institution between the 1st of January 2008 and the 31st of December 2018 were reviewed. A random subset (102 patients with 121 masses) was chosen to evaluate the reproducibility and repeatability of readers’ assessments. Readers evaluated non-contrast MRI scans retrospectively, assigned a 5-point score for the risk of malignancy and gave a specific diagnosis. The reference standard for the diagnosis was histopathology or at least one-year imaging follow-up. Diagnostic accuracy of the non-contrast MRI score was calculated. Inter- and intra-reader agreement was analyzed with Cohen’s kappa statistics. Results There were 53/350 (15.1%) malignant lesions in the whole cohort and 20/121 (16.5%) malignant lesions in the random subset. Good agreement between readers was found for the non-contrast MRI score (к = 0.73, 95% confidence interval [CI] 0.58–0.86) whilst the intra-reader agreement was excellent (к = 0.81, 95% CI 0.70–0.88). The non-contrast MRI score value of ≥ 4 was associated with malignancy with a sensitivity of 84.9%, a specificity of 95.9%, an accuracy of 94.2% and a positive likelihood ratio of 21 (area under the receiver operating curve 0.93, 95% CI 0.90–0.96). Conclusion Adnexal mass characterization on MRI without the administration of contrast medium has a high accuracy and excellent inter- and intra-reader agreement. Our results suggest that non-contrast studies may offer a reasonable diagnostic alternative when the administration of intravenous contrast medium is not possible. Key Points • A non-contrast pelvic MRI protocol may allow the characterization of adnexal masses with high accuracy. • The non-contrast MRI score may be used in clinical practice for differentiating benign from malignant adnexal lesions when the lack of intravenous contrast medium precludes analysis with the O–RADS MRI score.


2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Alain Winiger ◽  
Maria del Sol Pérez Lago ◽  
Dirk Lehnick ◽  
Justus E. Roos ◽  
Klaus Strobel

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