Frequency of Acute Kidney Injury Following Intravenous Contrast Medium Administration: A Systematic Review and Meta-Analysis

Radiology ◽  
2013 ◽  
Vol 267 (1) ◽  
pp. 119-128 ◽  
Author(s):  
Jennifer S. McDonald ◽  
Robert J. McDonald ◽  
Jules Comin ◽  
Eric E. Williamson ◽  
Richard W. Katzberg ◽  
...  
Keyword(s):  
Systematic Review ◽  
Acute Kidney Injury ◽  
Contrast Medium ◽  
Meta Analysis ◽  
Kidney Injury ◽  
Intravenous Contrast ◽  
Contrast Medium Administration ◽  
Intravenous Contrast Medium

Does intravenous contrast medium administration result in altered renal biomarkers? A study in clinically stable cats with and without azotemia

2021 ◽  
pp. 1098612X2110385
Author(s):  
Maria Laura Prüllage ◽  
Ilse Schwendenwein ◽  
Eva Eberspächer-Schweda ◽  
Sibylle Kneissl
Keyword(s):  
Contrast Media ◽  
Contrast Medium ◽  
Kidney Function ◽  
Kidney Injury ◽  
Intravenous Contrast ◽  
Post Contrast ◽  
Contrast Medium Administration ◽  
Intravenous Contrast Medium ◽  
Blood And Urine Samples ◽  
Contrast Media Administration

Objectives The aim of this study was to determine the prevalence of post-contrast acute kidney injury or comparable side effects on kidney function in cats receiving the non-ionic, iodinated agent ioversol and/or paramagnetic agent gadoteric acid. Methods Fifty-two animals were divided into four groups on the basis of contrast medium administration for imaging: ioversol (n = 27), gadoteric acid (n = 12), dual contrast media (n = 4) or control, which received an infusion of isotone intravenous fluids only during anaesthesia (n = 9). Blood and urine samples were obtained three times after contrast administration and compared with values obtained prior to administration of the contrast medium. Creatinine (<1.60 mg/dl), symmetric dimethylarginine (SDMA; ⩽14 μg/dl), urine protein:creatinine ratio (UPC; <0.2) and critical differences for creatinine (<0.3 mg/dl) and SDMA (<5.98 μg/dl) were measured. Results No significant short-term effects on mean creatinine, SDMA and UPC measurements were seen. Borderline proteinuria (UPC, 0.2–0.4) was detected in 11.4% of cases after contrast media administration. A UPC of more than 0.2 in five cases indicated that contrast media may affect kidney function, leading to (transient) proteinuria. Conclusions and relevance This study found no side effect on renal function following the administration of ioversol or gadoteric acid, provided patients were adequately hydrated. However, the clinical relevance of proteinuria in some cats needs to be evaluated in future studies.

Global Risk Factors of Contrast-Induced Acute Kidney Injury: Systematic Review and Meta-Analysis

2020 ◽  
Author(s):  
Yong Liu ◽  
Shiqun Chen ◽  
Edmund Y. M. Chung ◽  
Li Lei ◽  
Yibo He ◽  
...  
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Acute Kidney Injury ◽  
Meta Analysis ◽  
Kidney Injury ◽  
Global Risk
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