Psychophysically Determined Thresholds for Thermal Perception and Pain Perception in Healthy Women Across the Menstrual Cycle

2006 ◽  
Vol 22 (7) ◽  
pp. 610-616 ◽  
Author(s):  
Karin Soderberg ◽  
Inger Sundstrom Poromaa ◽  
Sigrid Nyberg ◽  
Torbjorn Backstrom ◽  
Erik Nordh
Keyword(s):  
Menstrual Cycle ◽  
Pain Perception ◽  
Thermal Perception ◽  
Healthy Women

Menstrual Cycle Modulation of Benzodiazepines Effects in Healthy Women

2009 ◽  
Author(s):  
Shanna Babalonis ◽  
Joshua A. Lile ◽  
Catherine A. Martin ◽  
Thomas H. Kelly
Keyword(s):  
Menstrual Cycle ◽  
Healthy Women

PP165-MON THE INFLUENCE OF MENSTRUAL CYCLE ON SERUM DIAMINE OXIDASE ACTIVITY IN HEALTHY WOMEN

2011 ◽  
Vol 6 (1) ◽  
pp. 176-177
Author(s):  
Y. Hamada ◽  
Y. Shinohara ◽  
M. Yano ◽  
M. Yamamoto ◽  
M. Yoshio ◽  
...  
Keyword(s):  
Menstrual Cycle ◽  
Oxidase Activity ◽  
Diamine Oxidase ◽  
Healthy Women ◽  
Diamine Oxidase Activity

The role of the menstrual cycle phase in pain perception before and after an isometric fatiguing contraction

2009 ◽  
Vol 106 (1) ◽  
pp. 105-112 ◽  
Author(s):  
Marie K. Hoeger Bement ◽  
Rebecca L. Rasiarmos ◽  
John M. DiCapo ◽  
Audrey Lewis ◽  
Manda L. Keller ◽  
...  
Keyword(s):  
Menstrual Cycle ◽  
Pain Perception ◽  
Cycle Phase ◽  
Menstrual Cycle Phase ◽  
Before And After

Excitatory and inhibitory pain mechanisms during the menstrual cycle in healthy women

Pain ◽  
2009 ◽  
Vol 146 (1) ◽  
pp. 47-55 ◽  
Author(s):  
Yannick Tousignant-Laflamme ◽  
Serge Marchand
Keyword(s):  
Menstrual Cycle ◽  
Pain Mechanisms ◽  
Healthy Women

scholarly journals Twice-Daily Subcutaneous Injection of Kisspeptin-54 Does Not Abolish Menstrual Cyclicity in Healthy Female Volunteers

2013 ◽  
Vol 98 (11) ◽  
pp. 4464-4474 ◽  
Author(s):  
C. N. Jayasena ◽  
A. N. Comninos ◽  
G. M. K. Nijher ◽  
A. Abbara ◽  
A. De Silva ◽  
...  
Keyword(s):  
Menstrual Cycle ◽  
Reproductive Function ◽  
Reproductive Hormones ◽  
Follicular Phase ◽  
Hypothalamic Amenorrhea ◽  
Healthy Women ◽  
Lh Pulsatility ◽  
Serum Lh ◽  
Healthy Female ◽  
Ultrasound Parameters

Background: Kisspeptin is a critical hypothalamic regulator of reproductive function. Chronic kisspeptin administration causes profound tachyphylaxis in male monkeys and in women with functional hypothalamic amenorrhea. The pharmacological effects of chronic kisspeptin exposure in healthy women with normal menstrual cycles have not been studied previously. Aim: Our aim was to determine the effects of follicular-phase kisspeptin-54 treatment on menstrual cyclicity in healthy women. Methods: We performed a prospective, single-blinded, 1-way crossover study. Healthy women received twice-daily sc injections of kisspeptin (6.4 nmol/kg) or 0.9% saline during menstrual days 7–14 (n = 5 per treatment arm). Serial assessments of basal reproductive hormones, ultrasound parameters, LH pulsatility, and acute sensitivity to GnRH and kisspeptin-54 injection were performed. Results: Menstrual cyclicity persisted in all women after follicular-phase kisspeptin-54 treatment. Chronic exposure to kisspeptin-54 did not abolish acute stimulation of LH after injection of kisspeptin-54 or GnRH. In addition, kisspeptin-54 treatment was associated with a shorter mean length of the menstrual cycle (mean length of menstrual cycle was 28.6 ± 1.4 days with saline vs 26.8 ± 3.1 days with kisspeptin, P < .01), earlier onset of highest recorded serum LH (mean menstrual day of highest LH was 15.2 ± 1.3 with saline vs 13.0 ± 1.9 with kisspeptin, P < .05), and earlier onset of the luteal phase (mean menstrual day of progesterone increase was 18.0 ± 2.1 with saline vs 15.8 ± 0.9 with kisspeptin, P < .05). Conclusion: Our data suggest that 1 week of exogenous kisspeptin-54 does not abolish menstrual cyclicity in healthy women. Further work is needed to determine whether kisspeptin could be used to treat certain anovulatory disorders.

scholarly journals Sex Differences, Hormone Fluctuations, Ankle Stability, and Dynamic Postural Control

2012 ◽  
Vol 47 (2) ◽  
pp. 143-148 ◽  
Author(s):  
Hayley Ericksen ◽  
Phillip A. Gribble
Keyword(s):  
Menstrual Cycle ◽  
Postural Control ◽  
Repeated Measures ◽  
Balance Test ◽  
Healthy Women ◽  
Ankle Stability ◽  
Ankle Arthrometer ◽  
Main Effect ◽  
Star Excursion Balance Test ◽  
Anterior Posterior

Context: Hormonal fluctuation as a risk factor in anterior cruciate ligament injury has been investigated with conflicting results. However, the influence of hormone fluctuations on ankle laxity and function has not been thoroughly examined. Objective: To examine the potential hormone contributions to ankle laxity and dynamic postural control during the preovulatory and postovulatory phases of the menstrual cycle using an ankle arthrometer and the Star Excursion Balance Test in healthy women. The cohort group consisted of male control participants. Design: Cohort study. Setting: Research laboratory. Patients or Other Participants: Twenty healthy women (age = 23.8 ± 6.50 years, height = 163.88 ± 8.28 cm, mass = 63.08 ± 12.38 kg) and 20 healthy men (age = 23.90 ± 4.15 years, height = 177.07 ± 7.60 cm, mass = 80.57 ± 12.20 kg). Intervention(s): Ankle stability was assessed with anterior-posterior and inversion-eversion loading. Dynamic postural control was assessed with the posteromedial reaching distance of the Star Excursion Balance Test. Main Outcome Measure(s): Female participants used ovulation kits for 3 months to determine the time of ovulation; during their preovulatory and postovulatory phases, they were tested in the laboratory with an ankle arthrometer and the Star Excursion Balance Test. Male participants were tested on similar dates as controls. For each dependent variable, a time by side by sex repeated-measures analysis of variance was performed. Statistical significance was set a priori at P < .05. Results: For anterior-posterior laxity, a side main effect was noted (F1,38 = 10.93, P = .002). For inversion-eversion laxity, a sex main effect was seen (F1,38 = 10.75, P = .002). For the posteromedial reaching task, a sex main effect was demonstrated (F1,38 = 8.72, P = .005). No influences of time on the dependent variables were evident. Conclusions: Although women presented with more ankle inversion-eversion laxity and less dynamic postural control, hormonal fluctuations during the menstrual cycle (preovulatory compared with postovulatory) did not affect ankle laxity or dynamic postural control, 2 factors that are associated with ankle instability.

The influence of vigorous aerobic exercise on serum brain-derived neurotrophic factor and estradiol in young, healthy women as a function of the menstrual cycle

2021 ◽  
Author(s):  
Sarah Ahmad ◽  
Rodney Hansen ◽  
Matthew Schmolesky
Keyword(s):  
Menstrual Cycle ◽  
Aerobic Exercise ◽  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
Cycle Exercise ◽  
Acute Bout ◽  
Healthy Women ◽  
Exercise Induced ◽  
Induced Changes ◽  
Serum Bdnf

AbstractResearch suggests strong inter-relationships between physical exercise, levels of brain-derived neurotrophic factor (BDNF), levels of estrogen, and the menstrual cycle, and yet no single study has examined these factors collectively in humans. The current study assessed the effect of an acute bout of vigorous aerobic exercise (20 minutes of stationary cycling at 80% of heart rate reserve) on serum BDNF and estradiol in healthy, eumenorrheic women, ages 18-28. In addition, this study determined whether basal BDNF or the exercise-induced increase in BDNF varies throughout the menstrual cycle. Thirty-four subjects were assigned to an experimental (n = 27) or control condition (n = 7). Exercise transiently increased both estradiol (51.2%) and BDNF (23.6%), and basal levels of BDNF and estradiol predicted the magnitude of the exercise-induced increases. Basal BDNF did not vary significantly throughout the menstrual cycle. Exercise-induced changes in BDNF did not correlate with menstrual cycle day or basal estradiol. Basal estradiol and basal BDNF showed a marginally significant positive correlation. Taken together, these results indicate that brief, vigorous aerobic exercise is sufficient to elevate both BDNF and estradiol in healthy women and that the menstrual cycle dramatically influences the magnitude of exercise-induced changes in estradiol, but not BDNF

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