Tight glycemic control increases metabolic distress in traumatic brain injury

2012 ◽  
Vol 40 (6) ◽  
pp. 1923-1929 ◽  
Author(s):  
Paul Vespa ◽  
David L. McArthur ◽  
Nathan Stein ◽  
Sung-Cheng Huang ◽  
Weber Shao ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Glycemic Control ◽  
Tight Glycemic Control

Glycemic Control in Neurocritically Ill Patients

2019 ◽  
pp. 241-245
Author(s):  
Carla P. Venegas-Borsellino ◽  
Michael A. Pizzi ◽  
Santiago Naranjo-Sierra
Keyword(s):  
Traumatic Brain Injury ◽  
Ischemic Stroke ◽  
Blood Glucose ◽  
Subarachnoid Hemorrhage ◽  
Brain Injury ◽  
Glycemic Control ◽  
Adverse Outcomes ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Poor Outcomes

Hyperglycemia, hypoglycemia, and variable blood glucose levels are associated with poor outcomes in critically ill patients. Patients with acute brain injury are sensitive to changes in glycemic levels because brain metabolism depends on a continuous, reliable supply of glucose. Numerous studies have shown that even moderate hypoglycemia may cause pronounced neuroglycopenia. Conversely hyperglycemia, which is prevalent in neurocritically ill patients, has been related to adverse outcomes after traumatic brain injury, ischemic stroke, intracranial hemorrhage, and subarachnoid hemorrhage.

scholarly journals Therapeutic effect of intensive glycemic control therapy in patients with traumatic brain injury

Medicine ◽  
2018 ◽  
Vol 97 (30) ◽  
pp. e11671 ◽  
Author(s):  
Chunran Zhu ◽  
Jinjing Chen ◽  
Junchen Pan ◽  
Zhichao Qiu ◽  
Tao Xu
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Glycemic Control ◽  
Therapeutic Effect ◽  
Intensive Glycemic Control ◽  
Control Therapy

Impact of tight glycemic control on cerebral glucose metabolism after severe brain injury: A microdialysis study*

2008 ◽  
Vol 36 (12) ◽  
pp. 3233-3238 ◽  
Author(s):  
Mauro Oddo ◽  
J Michael Schmidt ◽  
Emmanuel Carrera ◽  
Neeraj Badjatia ◽  
E Sander Connolly ◽  
...  
Keyword(s):  
Brain Injury ◽  
Glucose Metabolism ◽  
Glycemic Control ◽  
Tight Glycemic Control ◽  
Cerebral Glucose Metabolism ◽  
Severe Brain Injury ◽  
Microdialysis Study
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