VACCINE-STRAIN VARICELLA ZOSTER VIRUS CAUSING RECURRENT HERPES ZOSTER IN AN IMMUNOCOMPETENT 2-YEAR-OLD

2008 ◽  
Vol 27 (9) ◽  
pp. 847-848 ◽  
Author(s):  
Kaede Ota ◽  
Vy Kim ◽  
Sasson Lavi ◽  
Elizabeth L. Ford-Jones ◽  
Graham Tipples ◽  
...  
Keyword(s):  
Herpes Zoster ◽  
Varicella Zoster Virus ◽  
Vaccine Strain ◽  
Varicella Zoster ◽  
Recurrent Herpes

scholarly journals What is the True Etiology of “Recurrent Shingles”?

2021 ◽  
Vol 5 (1) ◽  
pp. 7-12
Author(s):  
Ramya Vangipuram ◽  
Harrison Nguyen ◽  
Stephen Tyring
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Zoster ◽  
Herpes Simplex ◽  
Varicella Zoster Virus ◽  
Varicella Zoster ◽  
Dermatology Clinic ◽  
Simplex Infection ◽  
Common Diagnosis ◽  
Recurrent Herpes ◽  
Simplex Virus

Purpose:  To determine the true etiology of cases of putative recurrent shingles referred to a dermatology clinic. Methods: A prospective cohort study of patients aged 15-87 years with reported recurrent herpes zoster was conducted. Vesicular fluid and serology for herpes simplex 1, 2, and varicella zoster virus immunoglobulins were obtained from patients presenting with vesicles. Biopsies were obtained from patients with ambiguous presentations. Results:  44 patients (56%) had evidence of herpes simplex virus infection. 32% of patients had positive herpes simplex virus cultures or polymerase chain reaction sequencing, and 24% additional patients were diagnosed with presumptive simplex infection based on elevated antibody titers. 44% of patients had a diagnosis other than zoster or simplex. One individual had a positive viral culture for varicella zoster virus. 99% of patients who presented with suspected recurrent herpes zoster had no definitive evidence of varicella zoster virus reactivation. Conclusions:  The most common diagnosis was herpes simplex infection. Our results suggest that true recurrent shingles in immunocompetent patients is rare.

scholarly journals Herpes Zoster Caused by Vaccine-Strain Varicella Zoster Virus in an Immunocompetent Recipient of Zoster Vaccine

2014 ◽  
Vol 58 (8) ◽  
pp. 1125-1128 ◽  
Author(s):  
H. F. Tseng ◽  
D. S. Schmid ◽  
R. Harpaz ◽  
P. LaRussa ◽  
N. J. Jensen ◽  
...  
Keyword(s):  
Herpes Zoster ◽  
Varicella Zoster Virus ◽  
Vaccine Strain ◽  
Zoster Vaccine ◽  
Varicella Zoster

scholarly journals Recurrent herpes zoster in the Shingles Prevention Study: Are second episodes caused by the same varicella-zoster virus strain?

Vaccine ◽  
2020 ◽  
Vol 38 (2) ◽  
pp. 150-157 ◽  
Author(s):  
Ruth Harbecke ◽  
Nancy J. Jensen ◽  
Daniel P. Depledge ◽  
Gary R. Johnson ◽  
Mark E. Ashbaugh ◽  
...  
Keyword(s):  
Herpes Zoster ◽  
Varicella Zoster Virus ◽  
Virus Strain ◽  
Prevention Study ◽  
Varicella Zoster ◽  
Recurrent Herpes

scholarly journals Herpes zoster recurrence within 1 month: A case report

2021 ◽  
Vol 19 ◽  
pp. 205873922110212
Author(s):  
Nan Zhao ◽  
Yulan Geng ◽  
Yexian Li ◽  
Lijuan Liu ◽  
Yanjia Li ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
Case Report ◽  
Herpes Zoster ◽  
B Cells ◽  
Varicella Zoster Virus ◽  
Lower Limit ◽  
Skin Disease ◽  
Clinical Manifestations ◽  
Varicella Zoster ◽  
Humoral Immune

Herpes zoster (HZ), caused by the varicella-zoster virus, is an infectious skin disease that rarely recurs after initial presentation. The mechanism underlying HZ recurrence is currently under investigation. In this article, we report a case of HZ relapse within 1 month. Analysis of patient’s clinical manifestations, histopathological features, and flow cytometry results indicated that the absolute and percentage values of B cells were below the lower limit. We hypothesized that the patient had abnormal humoral immune function, which may be one reason leading to the HZ relapse within 1 month. The findings of this case will serve as useful reference for HZ recurrence for clinicians. This case was impactful and added to the literature on HZ recurrence.

scholarly journals Incidence of herpes zoster and seroprevalence of varicella-zoster virus in young adults of South Korea

2008 ◽  
Vol 12 (3) ◽  
pp. 245-247 ◽  
Author(s):  
Cheol-In Kang ◽  
Chang-Min Choi ◽  
Tae-Sung Park ◽  
Dong-Jun Lee ◽  
Myoung-don Oh ◽  
...  
Keyword(s):  
Young Adults ◽  
Herpes Zoster ◽  
South Korea ◽  
Varicella Zoster Virus ◽  
Varicella Zoster

scholarly journals Varicella Zoster Virus-Associated Meningitis as a Rebound Varicella Zoster Disease after Antiviral Discontinuation

2021 ◽  
pp. 148-153
Author(s):  
Tetsuko Sato ◽  
Takenobu Yamamoto ◽  
Yumi Aoyama
Keyword(s):  
Herpes Zoster ◽  
Early Diagnosis ◽  
Varicella Zoster Virus ◽  
Immunosuppressive Therapy ◽  
Unusual Case ◽  
Cranial Nerves ◽  
Skin Lesions ◽  
Immunocompromised Patients ◽  
Aggressive Treatment ◽  
Varicella Zoster

Varicella zoster virus (VZV)-associated meningitis is usually progressive and can be fatal, and early diagnosis and aggressive treatment with intravenous antivirals such as acyclovir (ACV) are required in immunocompromised patients. Patients receiving corticosteroids and immunosuppressive therapy have a significantly higher risk of VZV-associated meningitis. In this report, we describe an unusual case of herpes zoster (HZ) in a young woman who was first diagnosed during tapering of prednisone for dermatomyositis. The skin lesions affected the left L2 and L3 dermatomes, which is unusual in VZV-associated meningitis. Despite showing a good rapid response to antivirals, she developed VZV-associated meningitis immediately after discontinuation of ACV. This phenomenon is often called rebound VZV reactivation disease and occurs after discontinuation of antivirals. This case was notable in that the affected dermatomes were distant from the cranial nerves. Thus, progression of HZ to VZV reactivation-associated meningitis can occur even in appropriately treated HZ patients. Continuation of antivirals beyond 1 week in patients on immunosuppressive therapy may be associated with a decreased risk of severe rebound VZV disease, such as VZV-associated meningitis.

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