Laparoscopic pancreaticoduodenectomy for a big co-secretor neuroendocrine tumor in the head of the pancreas

Victor Vasquez; Ramón Alvarado; Kewin Quispe-de la Roca; Leila Oliveros; Daniel Giraldo; Jaime Villena

doi:10.1097/md9.0000000000000220

Laparoscopic pancreaticoduodenectomy for a big co-secretor neuroendocrine tumor in the head of the pancreas

Medicine: Case Reports and Study Protocols ◽

10.1097/md9.0000000000000220 ◽

2022 ◽

Vol 3 (1) ◽

pp. e0220

Author(s):

Victor Vasquez ◽

Ramón Alvarado ◽

Kewin Quispe-de la Roca ◽

Leila Oliveros ◽

Daniel Giraldo ◽

...

Keyword(s):

Neuroendocrine Tumor ◽

Laparoscopic Pancreaticoduodenectomy ◽

Head Of The Pancreas

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Laparoscopic pancreaticoduodenectomy in A-92-older Chinese patient for cancer of head of the pancreas

Medicine ◽

10.1097/md.0000000000005962 ◽

2017 ◽

Vol 96 (3) ◽

pp. e5962 ◽

Cited By ~ 4

Author(s):

Jiayu Zhou ◽

Chang Xin ◽

Tao Xia ◽

Yiping Mou ◽

Xiaowu Xu ◽

...

Keyword(s):

Chinese Patient ◽

Laparoscopic Pancreaticoduodenectomy ◽

Head Of The Pancreas ◽

Older Chinese

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Total laparoscopic pancreaticoduodenectomy for patients with tumor of the head of the pancreas and periampullare area

Pancreatology ◽

10.1016/j.pan.2013.04.165 ◽

2013 ◽

Vol 13 (3) ◽

pp. S48-S49

Author(s):

Igor Khatkov ◽

Viktor Tsvirkun ◽

Roman Izrailov ◽

Pavel Tyutyunnik

Keyword(s):

Laparoscopic Pancreaticoduodenectomy ◽

Head Of The Pancreas

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Influence of organ location and sex of patient on pancreatic neuroendocrine tumor 5-year survival.

Journal of Clinical Oncology ◽

10.1200/jco.2017.35.15_suppl.e15713 ◽

2017 ◽

Vol 35 (15_suppl) ◽

pp. e15713-e15713

Author(s):

Gregory P. Botta ◽

Munveer Singh Bhangoo ◽

Darren Sigal

Keyword(s):

Pancreatic Cancer ◽

Neuroendocrine Tumor ◽

Pancreatic Neuroendocrine Tumor ◽

Large Cell ◽

The Body ◽

Female Patients ◽

Kaplan Meier ◽

Head Of The Pancreas ◽

Male Patients ◽

Medicare Database

e15713 Background: Pancreatic neuroendocrine tumors (PNET) represent a rare tumor histology among patients diagnosed with pancreatic cancer (less than 2% incidence). These tumors arise from the endocrine tissues of the pancreas and can present with a variable clinical course. We sought to examine the overall survival (OS) of patients based upon sex and anatomic location via the SEER database. Methods: Accessing the SEER-Medicare database, we identified 3,242 patients with both Pancreatic Cancer and Neuroendocrine Tumor (NET) histologic validation using ICD-O-3 Codes while excluding Large Cell, Small Cell, and Mixed Endocrine-Exocrine tumors. We then sub-stratified the data to male (N = 1816) and female (N = 1426) sex as well as pancreatic location: Head (Male = 831; Female = 657), Body (Male = 283; Female = 258), or Tail (Male = 701; Female = 510). We excluded PNETs of the pancreatic duct as there were only 2 cases (Male = 1; Female = 1). All comparison tests were run with SEER*STAT 8.3.2 via a Two-Sample t-Test Assuming Equal Variances. OS was analyzed using the Kaplan–Meier method. Results: Overall, both Male and Female patients with PNET have significantly improved 5-Year survival compared with those patients with Pancreatic Adenocarcinoma ((47.47% (n = 3242) vs 6.6% (n = 117,204), p < 0.05). There is no difference in 5-Year OS between Male (44.9%) and Female (50.5%) patients with PNET accounting for all locations. There is a trend towards significance in improved 5-Year OS in Female patients with Tail PNET versus Male patients with Tail PNET (55.8% (n = 510) vs 48.6% (n = 701), p < 0.06). Significantly, Female patients with Tail PNET have a significantly higher 5-Year OS compared to Female patients with Head PNET (55.8% (n = 510) vs 46.9% (n = 657), p < 0.05). There was a trend towards improved 5-Year OS in Female patients with Tail PNET versus those within the Body (55.8% (n = 510) vs 48.6% (n = 258), p < 0.01). Conclusions: Based upon this population study, Female patients with PNET localized to the Tail have a significantly higher 5-Year OS than Female patients with PNET localized to the Head of the Pancreas. These same patients trend towards improved survival when compared with Female patients with Body PNET as well as Male patients with Tail PNET.

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