scholarly journals Supporting COVID-19 policy response with large-scale mobility-based modeling

Author(s):  
Serina Chang ◽  
Mandy L. Wilson ◽  
Bryan Lewis ◽  
Zakaria Mehrab ◽  
Komal K. Dudakiya ◽  
...  

ABSTRACTSocial distancing measures, such as restricting occupancy at venues, have been a primary intervention for controlling the spread of COVID-19. However, these mobility restrictions place a significant economic burden on individuals and businesses. To balance these competing demands, policymakers need analytical tools to assess the costs and benefits of different mobility reduction measures.In this paper, we present our work motivated by our interactions with the Virginia Department of Health on a decision-support tool that utilizes large-scale data and epidemiological modeling to quantify the impact of changes in mobility on infection rates. Our model captures the spread of COVID-19 by using a fine-grained, dynamic mobility network that encodes the hourly movements of people from neighborhoods to individual places, with over 3 billion hourly edges. By perturbing the mobility network, we can simulate a wide variety of reopening plans and forecast their impact in terms of new infections and the loss in visits per sector. To deploy this model in practice, we built a robust computational infrastructure to support running millions of model realizations, and we worked with policymakers to develop an intuitive dashboard interface that communicates our model’s predictions for thousands of potential policies, tailored to their jurisdiction. The resulting decision-support environment provides policymakers with much-needed analytical machinery to assess the tradeoffs between future infections and mobility restrictions.

2005 ◽  
Vol 2005 ◽  
pp. 28-28
Author(s):  
P. K. Thornton ◽  
P. J. Thorne ◽  
C. Quiros ◽  
D. Sheikh ◽  
R. L. Kruska ◽  
...  

Extrapolate (EX-ante Tool for RAnking POLicy AlTErnatives) is a decision support tool to assess the impact of policy measures on different target groups. It is designed to serve as a “filter” that, given the broad characteristics of the population, allows the user to sift through different policy measures to assess ex ante the broad potential impacts of these before deciding to look at particular policy options in more detail. Extrapolate models, in a very simple way, the impact of changes on constraints facing potential beneficiary groups, and how these may affect outcomes and their livelihood status. Extrapolate now makes use of mapping facilities from another decision-support tool, PRIMAS (Poverty Reduction Intervention Mapping in Agricultural Systems), that allows the user to match characteristics of particular technological options and constraints with the spatial characteristics of particular target groups in the landscape.


2020 ◽  
Vol 21 (6) ◽  
pp. 375-386 ◽  
Author(s):  
Christina L Aquilante ◽  
David P Kao ◽  
Katy E Trinkley ◽  
Chen-Tan Lin ◽  
Kristy R Crooks ◽  
...  

In recent years, the genomics community has witnessed the growth of large research biobanks, which collect DNA samples for research purposes. Depending on how and where the samples are genotyped, biobanks also offer the potential opportunity to return actionable genomic results to the clinical setting. We developed a preemptive clinical pharmacogenomic implementation initiative via a health system-wide research biobank at the University of Colorado. Here, we describe how preemptive return of clinical pharmacogenomic results via a research biobank is feasible, particularly when coupled with strong institutional support to maximize the impact and efficiency of biobank resources, a multidisciplinary implementation team, automated clinical decision support tools, and proactive strategies to engage stakeholders early in the clinical decision support tool development process.


2019 ◽  
Vol 191 ◽  
pp. 131-141
Author(s):  
Miguel A. Gabarron-Galeote ◽  
Jacqueline A. Hannam ◽  
Thomas Mayr ◽  
Patrick J. Jarvis

Author(s):  
Ed Owens ◽  
Elliott Taylor ◽  
Chunjiang An ◽  
Zhi Chen ◽  
George Danner ◽  
...  

ABSTRACT #1141234 The coastal waters of Canada embrace a wide range of physical environments and ecosystems from the warm, sediment-rich waters of the Bay of Fundy to the nutrient-limited cold waters of the high Arctic. This range of biophysical characteristics impacts natural attenuation and weathering processes for oil stranded on shorelines. This study was conducted to: 1) identify and quantify the primary regional parameters that control shoreline oil translocation (removal) processes and pathways and 2) define the effectiveness and environmental consequences of current and potential oiled shoreline treatment strategies and tactics. A specific knowledge gap, here and elsewhere in the world, has been in understanding how the distribution and character of fine-grained sediments affect stranded oil attenuation. Fine-grained sediments (<1mm) can play a critical role in natural or induced (that is, shoreline treatment) oil dispersal. Shoreline sediment samples were collected and analyzed from representative locations on Arctic, Atlantic, and Pacific Ocean beaches to provide a broad geographic characterization of mineral fines at the regional level. This knowledge is the basis for an “Oiled Shoreline Response Program (SRP) Decision Support Tool” to aid spill scientists, students, environmental resource managers, spill responders and the public in understanding the response methods and the ramifications and consequences of their shoreline treatment options without the need to digest technical papers, large reports, or data bases. This MPRI SRP Decision Support Tool is intended to be a dynamic, interactive, multi-layered, geographically and seasonally-based model for shoreline oil spill response decision analyses. A goal of this interactive model is to move away from the traditional static format of learning from explanations in text reports and publications to an interactive tool that encourages its users to explore and fully understand the significance of the different environmental factors outlined in publications and data bases. Recent advances in web technology make this possible. The development of user interface platforms such as React, libraries such as D3, and notebook forms like Observable has created a palette of technologies that together make web application patterns such as Documodels a much more streamlined development process. The power of this medium is to convey a complex subject and to enable a user to grasp keen insights and so understand the consequences of intervention decisions.


2014 ◽  
Vol 22 (1) ◽  
pp. 1-20
Author(s):  
Jasenka Rakas ◽  
Michael Seelhorst ◽  
Bona Bernard Niu ◽  
Jeffrey Tom ◽  
Confesor Santiago

Author(s):  
Aleksandra Krstikj ◽  
Moisés Gerardo Contreras Ruiz Esparza ◽  
Jaime Mora Vargas ◽  
Laura Hervert Escobar ◽  
Cecilia López de la Rosa ◽  
...  

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