Astrophysical tests of current values for dimensionless constants known on Earth, such as the fine-structure constant, α , and proton-to-electron mass ratio, μ = m p / m e , are communicated using data from high-resolution quasar spectra in different regions or epochs of the universe. The symmetry wavelengths of [Fe II] lines from redshifted quasar spectra of J110325-264515 and their corresponding values in the laboratory were combined to find a new limit on space-time variations in the proton-to-electron mass ratio, ∆ μ / μ = ( 0.096 ± 0.182 ) × 10 − 7 . The results show how the indicated astrophysical observations can further improve the accuracy and space-time variations of physics constants.