scholarly journals Magnetite nanoparticles for nonradionuclide brachytherapy

2015 ◽  
Vol 48 (3) ◽  
pp. 690-692
Author(s):  
Victor Safronov ◽  
Evgeny Sozontov ◽  
Mikhail Polikarpov

Magnetite nanoparticles possess several properties that can make them useful for targeted delivery of radiation to tumors for the purpose of brachytherapy. Such particles are biodegradable and magnetic and can emit secondary radiation when irradiated by an external source. In this work, the dose distribution around a magnetite particle of 10 nm diameter being irradiated by monochromatic X-rays with energies in the range 4–60 keV is calculated.

Science ◽  
1950 ◽  
Vol 111 (2889) ◽  
pp. 514-516 ◽  
Author(s):  
J. S. Laughlin ◽  
W. D. Davies

1964 ◽  
Vol 21 (3) ◽  
pp. 462 ◽  
Author(s):  
Stanley J. Malsky ◽  
Charles G. Amato ◽  
Victor P. Bond ◽  
James S. Robertson ◽  
Bernard Roswit
Keyword(s):  

2020 ◽  
Vol 15 (04) ◽  
pp. P04001-P04001
Author(s):  
Sung Jin Noh ◽  
HyoJin Kim ◽  
Hyun Kim ◽  
Jeung kee Kim ◽  
Chi-Woong Mun ◽  
...  

2011 ◽  
Vol 694 ◽  
pp. 205-208 ◽  
Author(s):  
Аndrey Nikolaevich Belousov

Nowadays nanotechnology as a new direction of science allows to develop therapeutic methods of the endogenous intoxication syndrome and to create a new class of biocompatible sorbents. In Ukraine first preparations of medical nanotechnology were produced and patented in 1998. These are “IKBB” intracorporeal biocorrector, magnet-controlled sorbent (MCS-B), and “Micromage-B”. The preparations are based on colloid magnetite particles (Fe3O4) from 6 to 12 nm. Adsorption layer provides a high sorption activity to magnetite nanoparticles. Total activity of their sorption surface is 800 – 1200 m2/g, magnetic field intensity produced by each particle is 300 - 400 kA/m, ζ – potential is – 19 mV. Each magnetite particle is a subdomain elementary magnetite of a sphere shape. The main biological action of nanotechnology preparations is direct to regulation of cell metabolism. Therapeutic effect of this preparation is based on the influence of adsorption process and of constant magnetic field that surrounds colloid magnetite particle on cellular and subcellular structures. Point of attack is surface proteins of cell membranes. Colloid magnetite particles modify composition of protein molecules thereby effecting transport of substances to a cell. Using magnet-controlled sorbent the method of extracorporal hemocorrection on the whole is rather the method of effective and reliable way to activate natural processes of detoxication of organism, than the method of artificial detoxication. The absence of contra-indication and incidental effects (haematic, haemodynamic, hormone, electrolytic, immune) creates real predisposition for using this method in intensive therapy of intoxication syndrome.


1905 ◽  
Vol 74 (497-506) ◽  
pp. 474-475 ◽  
Author(s):  
Charles Glover Barkla ◽  
Joseph John Thomson
Keyword(s):  

Experiments on secondary radiation from gases and light solids subject to X-rays showed that the character of this radiation differs only very slightly from that of the radiation producing it, and that the energy of this radiation is proportional merely to the quantity of matter through which a beam of Röntgen radiation of definite intensity passes, being independent of the kind of matter.


2011 ◽  
Vol 2 (0) ◽  
pp. 312-317 ◽  
Author(s):  
Nobuteru NARIYAMA ◽  
Keiji UMETANI ◽  
Kunio SHINOHARA ◽  
Takeshi KONDOH ◽  
Ai KURIHARA ◽  
...  

1994 ◽  
Vol 29 (4) ◽  
pp. 411-416 ◽  
Author(s):  
Hideki KATO ◽  
Masatoshi TSUZAKA ◽  
Shuji KOYAMA ◽  
Shoichi SUZUKI ◽  
Takeo ORITO ◽  
...  

1942 ◽  
Vol 20a (11) ◽  
pp. 185-194
Author(s):  
G. A. Wrenshall ◽  
H. J. Nichols

Using an ionization chamber method, the intensity distribution and quality of forward transmitted secondary X-rays from filters of aluminium, copper, tin, and lead have been measured under standard operating conditions. Geometrical arrangements of X-ray tube, defining apertures, filter, and receiver commonly used in medical and industrial radiology are employed. Suggestions for minimizing the intensity of the secondary radiation reaching the receiver from single-metal filters are submitted.


The manner of our attack upon the problems of radioactivity, including the action of the Röntgen rays, depends materially on whether we suppose that an atom can or can not be made to yield energy from an internal store. In the former case we have nothing to guide us to an estimate of how much energy may be expected to be put into circulation in this way. If, for example, a β -ray in passing through an atom prompts the atom to emit new secondary radiation with energy drawn from a source usually beyond the reach of transformation into physical or chemical or other known forms, or if the atom sometimes absorbs energy from that of the β -ray motion and locks it up, then the quantities of energy thus added to or subtracted from the amounts we may hope to measure must be no more than subjects of experiment. We shall have to be content with registering them without accounting for them. But if we take the second of the two alternatives the problem is immensely simplified, and we may work for a more complete solution. An α -ray or β -ray begins its career with so much energy. While we cannot, of course, explain this initial liberation of energy, we may try to account completely for its subsequent expenditure in various ways, since we have no unknown or unexpected items to take into account on either side of the balance-sheet. Exactly the same statement can be made in respect to each X- or γ -ray, since each such ray, as has been shown in previous papers, can be considered by itself, being independent of all its companions in what we call a “beam of X- or of γ -rays.” Energy considerations lead us directly to the supposition that the X- and γ -rays are corpuscular in nature in so far as each ray is a separate identity moving through space unaltered in form and energy- content, just as an unhindered projectile would do. No X- or γ -ray spends energy in its passage through matter; the only way in which the existence of such rays is made manifest is through their replacement by swiftly moving electrons which ionise the gas through which they pass. The single X-ray disappears as such, and in its place is a cathode ray, an electron moving with energy inherited from the X-ray. Ionisation by X- or γ -rays is an indirect process.


Sign in / Sign up

Export Citation Format

Share Document