Optical coherence tomography: Current biomedical applications and future clinical utility

Author(s):  
B. A. Standish ◽  
M. K. K. Leung ◽  
A. L. Mariampillai ◽  
V. X. D. Yang
2021 ◽  
pp. 247412642199733
Author(s):  
Kyle D. Kovacs ◽  
M. Abdallah Mahrous ◽  
Luis Gonzalez ◽  
Benjamin E. Botsford ◽  
Tamara L. Lenis ◽  
...  

Purpose: This work aims to evaluate the clinical utility and feasibility of a novel scanning laser ophthalmoscope-based navigated ultra-widefield swept-source optical coherence tomography (UWF SS-OCT) imaging system. Methods: A retrospective, single-center, consecutive case series evaluated patients between September 2019 and October 2020 with UWF SS-OCT (modified Optos P200TxE, Optos PLC) as part of routine retinal care. The logistics of image acquisition, interpretability of images captured, nature of the peripheral abnormality, and clinical utility in management decisions were recorded. Results: Eighty-two eyes from 72 patients were included. Patients were aged 59.4 ± 17.1 years (range, 8-87 years). During imaging, 4.4 series of images were obtained in 4.1 minutes, with 86.4% of the image series deemed to be diagnostic of the peripheral pathology on blinded image review. The most common pathologic findings were chorioretinal scars (18 eyes). In 31 (38%) eyes, these images were meaningful in supporting clinical decision-making with definitive findings. Diagnoses imaged included retinal detachment combined with retinoschisis, retinal hole with overlying vitreous traction and subretinal fluid, vitreous inflammation overlying a peripheral scar, Coats disease, and peripheral retinal traction in sickle cell retinopathy. Conclusions: Navigated UWF SS-OCT imaging was clinically practical and provided high-quality characterization of peripheral retinal lesions for all eyes. Images directly contributed to management plans, including laser, injection or surgical treatment, for a clinically meaningful set of patients (38%). Future studies are needed to further assess the value of this imaging modality and its role in diagnosing, monitoring, and treating peripheral lesions.


2009 ◽  
Vol 20 (1) ◽  
pp. 111-118 ◽  
Author(s):  
Brett E Bouma ◽  
Seok-Hyun Yun ◽  
Benjamin J Vakoc ◽  
Melissa J Suter ◽  
Guillermo J Tearney

2020 ◽  
Vol 10 (5) ◽  
pp. 1389-1414
Author(s):  
Vijayakumar Subban ◽  
Owen Christopher Raffel

2011 ◽  
Vol 3 (3) ◽  
pp. 155-169 ◽  
Author(s):  
Dan P. Popescu ◽  
Lin-P’ing Choo-Smith ◽  
Costel Flueraru ◽  
Youxin Mao ◽  
Shoude Chang ◽  
...  

2020 ◽  
Vol 29 (6) ◽  
pp. 874-882 ◽  
Author(s):  
Kamran Majeed ◽  
Eline Hartman ◽  
Trevor A. Mori ◽  
Richard Alcock ◽  
Jon Spiro ◽  
...  

2020 ◽  
Vol 29 (9) ◽  
pp. 823-830
Author(s):  
Andrew J. Nelson ◽  
Zhongdi Chu ◽  
Bruce Burkemper ◽  
Brenda R. Chang ◽  
Benjamin Xu ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document