P6B-13 In Vivo Blood Flow Imaging of Achilles Tendon in Mice with High Frequency Ultrasound

2007 ◽  
Author(s):  
Meng-Lin Li ◽  
Jer-Junn Luh ◽  
Jia-Jiun Chen ◽  
Chih-Kuang Yeh
Keyword(s):  
Blood Flow ◽  
Achilles Tendon ◽  
High Frequency ◽  
Flow Imaging ◽  
High Frequency Ultrasound ◽  
Blood Flow Imaging ◽  
Frequency Ultrasound

In vivo imaging of blood flow in the mouse Achilles tendon using high-frequency ultrasound

Ultrasonics ◽  
2009 ◽  
Vol 49 (2) ◽  
pp. 226-230 ◽  
Author(s):  
Chih-Kuang Yeh ◽  
Jia-Jiun Chen ◽  
Meng-Lin Li ◽  
Jer-Junn Luh ◽  
Jia-Jin Jason Chen
Keyword(s):  
Blood Flow ◽  
Achilles Tendon ◽  
In Vivo Imaging ◽  
High Frequency ◽  
High Frequency Ultrasound ◽  
Frequency Ultrasound

Optimization of real-time high-frequency ultrasound for blood flow imaging in the microcirculation

2001 ◽  
Author(s):  
Dustin E. Kruse ◽  
Jerome J. Mai ◽  
Ronald H. Silverman ◽  
Michael F. Insana ◽  
D. J. Coleman ◽  
...  
Keyword(s):  
Blood Flow ◽  
Real Time ◽  
High Frequency ◽  
Flow Imaging ◽  
High Frequency Ultrasound ◽  
Blood Flow Imaging ◽  
Frequency Ultrasound

A Method for Gray-Scale Imaging of Blood Flow Using High-Frequency Ultrasound

2017 ◽  
Vol 40 (1) ◽  
pp. 3-14
Author(s):  
Jun Yang ◽  
Chao Pang ◽  
Xue-Dong Song ◽  
Xuan Gao
Keyword(s):  
Blood Flow ◽  
High Frequency ◽  
Single Pulse ◽  
Frequency Range ◽  
High Frequency Ultrasound ◽  
Blood Flow Imaging ◽  
Blood Flow Signal ◽  
Flow Information ◽  
Blood Imaging ◽  
Frequency Ultrasound

This paper presents a new method that complements current techniques available in the high-frequency blood imaging field. A comprehensive scattering model was established to determine the feasibility and frequency range of the blood flow imaging of superficial organs and tissues using high-frequency ultrasound. The transmitting and receiving modes and an algorithm were designed to obtain blood flow information based on differentiation between tissues and blood flow. The system was created and tested first with a model that simulates blood flow and was then used on human tissue. A fine-scale image of a blood vessel could be obtained with this system. Moreover, this method can obtain weak blood flow signal using single pulse rather than the traditional pulse-code method and maintains a high resolution that can be matched to high-frequency structural imaging. This study provides a reliable method for further applications related to diagnoses of superficial organs.

scholarly journals Analysis of Collagen Organization in Mouse Achilles Tendon Using High-Frequency Ultrasound Imaging

2014 ◽  
Vol 136 (2) ◽  
Author(s):  
Corinne N. Riggin ◽  
Joseph J. Sarver ◽  
Benjamin R. Freedman ◽  
Stephen J. Thomas ◽  
Louis J. Soslowsky
Keyword(s):  
Achilles Tendon ◽  
Ultrasound Imaging ◽  
High Frequency ◽  
Tendon Healing ◽  
Tendon Injury ◽  
High Frequency Ultrasound ◽  
Collagen Organization ◽  
Collagen Alignment ◽  
Frequency Ultrasound

Achilles tendon ruptures are traumatic injuries, and techniques for assessing repair outcomes rely on patient-based measures of pain and function, which do not directly assess tendon healing. Consequently, there is a need for a quantitative, in vivo measure of tendon properties. Therefore, the purpose of this study was to validate ultrasound imaging for evaluating collagen organization in tendons. In this study, we compared our novel, high-frequency ultrasound (HFUS) imaging and analysis method to a standard measure of collagen organization, crossed polarizer (CP) imaging. Eighteen mouse Achilles tendons were harvested and placed into a testing fixture where HFUS and CP imaging could be performed simultaneously in a controlled loading environment. Two experiments were conducted: (1) effect of loading on collagen alignment and (2) effect of an excisional injury on collagen alignment. As expected, it was found that both the HFUS and CP methods could reliably detect an increase in alignment with increasing load, as well as a decrease in alignment with injury. This HFUS method demonstrates that structural measures of collagen organization in tendon can be determined through ultrasound imaging. This experiment also provides a mechanistic evaluation of tissue structure that could potentially be used to develop a targeted approach to aid in rehabilitation or monitor return to activity after tendon injury.

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