scholarly journals Heat shock proteins are differentially expressed in brain and spinal cord: implications for multiple sclerosis

2018 ◽  
Vol 194 (2) ◽  
pp. 137-152 ◽  
Author(s):  
R. P. Gorter ◽  
E. Nutma ◽  
M.-C. Jahrei ◽  
J. C. de Jonge ◽  
R. A Quinlan ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Spinal Cord ◽  
Heat Shock ◽  
Heat Shock Proteins ◽  
Differentially Expressed ◽  
Shock Proteins ◽  
Brain And Spinal Cord

Heat Shock Proteins in Multiple Sclerosis

2009 ◽  
pp. 101-111 ◽  
Author(s):  
Celia F. Brosnan ◽  
Luca Battistini ◽  
Krzysztof Selmaj
Keyword(s):  
Multiple Sclerosis ◽  
Heat Shock ◽  
Heat Shock Proteins ◽  
Shock Proteins

T-lymphocyte reactivity to the recombinant mycobacterial 65- and 70-kDa heat shock proteins in multiple sclerosis

1992 ◽  
Vol 5 (6) ◽  
pp. 691-702 ◽  
Author(s):  
Marco Salvetti ◽  
Carla Buttinelli ◽  
Giovanni Ristori ◽  
Maurizio Carbonari ◽  
Michela Cherchi ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Heat Shock ◽  
Heat Shock Proteins ◽  
T Lymphocyte ◽  
Shock Proteins ◽  
Lymphocyte Reactivity

Heat-shock proteins and autoimmunity: Implications for multiple sclerosis

1993 ◽  
Vol 34 (1) ◽  
pp. 5-7 ◽  
Author(s):  
Richard M. Runsohoff ◽  
Richard A. Rudich
Keyword(s):  
Multiple Sclerosis ◽  
Heat Shock ◽  
Heat Shock Proteins ◽  
Shock Proteins

Heat shock proteins as targets for ?-? T cells in multiple sclerosis

1992 ◽  
Vol 32 (3) ◽  
pp. 410-410 ◽  
Author(s):  
Marchco Salvetti ◽  
Carla Buttinelli ◽  
Giovanni Ristori ◽  
Cesare Fieschi
Keyword(s):  
Multiple Sclerosis ◽  
T Cells ◽  
Heat Shock ◽  
Heat Shock Proteins ◽  
Shock Proteins

Heat shock proteins are differentially expressed in human gastrointestinal cancers

1995 ◽  
Vol 4 (4) ◽  
pp. 197-203 ◽  
Author(s):  
J.A. Ehrenfried ◽  
B.E. Herron ◽  
C.M. Townsend ◽  
B.M. Evers
Keyword(s):  
Heat Shock ◽  
Heat Shock Proteins ◽  
Differentially Expressed ◽  
Gastrointestinal Cancers ◽  
Shock Proteins

scholarly journals The role of heat shock proteins in spinal cord injury

2008 ◽  
Vol 25 (5) ◽  
pp. E4 ◽  
Author(s):  
Sangala Jaypal Reddy ◽  
Frank La Marca ◽  
Paul Park
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Heat Shock ◽  
Heat Shock Proteins ◽  
Motor Neurons ◽  
Ependymal Cells ◽  
Neuroprotective Effects ◽  
Experimental Drugs ◽  
Cord Injury ◽  
Shock Proteins

Heat shock proteins (HSPs) are normal intracellular proteins that are produced in greater amounts when cells are subjected to stress or injury. These proteins have been shown to play a key role in the modulation of the secondary injury that occurs after the initial spinal cord injury (SCI). Heat shock proteins normally act as molecular chaperones and are called protein guardians because they act to repair partially damaged proteins. Normally intracellular, HSPs can also be liberated into the systemic circulation to act as important inflammatory mediators. In the setting of SCI, HSP induction has been shown to be beneficial. These proteins are liberated primarily by acutely stressed microglial, endothelial, and ependymal cells. Heat shock proteins have also been shown to assist in the protection of motor neurons and to prevent chronic inflammation after SCI. In animal models, several experimental drugs have shown neuroprotective effects in the spinal cord and appear to function by modulating HSPs.

scholarly journals Heat Shock Proteins and Multiple Sclerosis

1996 ◽  
Vol 55 (4) ◽  
pp. 389-402 ◽  
Author(s):  
Celia F. Brosnan ◽  
Luca Battistini ◽  
Yan-ling Gao ◽  
Cedric S. Raine ◽  
Dennis A. Aquino
Keyword(s):  
Multiple Sclerosis ◽  
Heat Shock ◽  
Heat Shock Proteins ◽  
Shock Proteins

The potential role of heat shock proteins in acute spinal cord injury

2014 ◽  
Vol 23 (7) ◽  
pp. 1480-1490 ◽  
Author(s):  
Yijun Zhou ◽  
Leilei Xu ◽  
Xinghua Song ◽  
Liwen Ding ◽  
Jiangtao Chen ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Heat Shock ◽  
Heat Shock Proteins ◽  
Potential Role ◽  
Acute Spinal Cord Injury ◽  
Cord Injury ◽  
Shock Proteins
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