Prospective PC-interactive Pressure Algesimetry of Post-Traumatic Neck pain after Whiplash Injury

Cephalalgia ◽  
2005 ◽  
Vol 25 (3) ◽  
pp. 205-213 ◽  
Author(s):  
K Nebel ◽  
P Stude ◽  
C Lüdecke ◽  
H Wiese ◽  
H-C Diener ◽  
...  
Keyword(s):  
Muscle Pain ◽  
Whiplash Injury ◽  
Acute Stage ◽  
Acute Injury ◽  
Systematic Analysis ◽  
Pressure Pain ◽  
Healthy Control ◽  
Post Traumatic ◽  
Recovery Dynamics ◽  
Whiplash Syndrome

Cervical pain is a prominent symptom in both acute whiplash injury and late whiplash syndrome. However, no systematic analysis of post-traumatic pain development covering several weeks has yet been performed in whiplash patients. It was the aim of the present study to analyse the duration and course of post-traumatic muscle pain due to whiplash injury in a prospective follow-up examination with short investigation intervals. A recovery of initially increased muscle pain after whiplash injury within 1 month was hypothesized. Pressure pain of the splenius and trapezius muscles was recorded using PC-interactive pressure algesimetry. Whiplash patients were investigated during the acute injury stage and after 3, 4, and 6 weeks and compared with matched controls. We found significantly increased pressure pain of the splenius and trapezius muscles in the acute stage of whiplash injury. After 4 weeks patients' scores of pain parameters were comparable to those of healthy control subjects. Within the patient group the first changes of pressure pain were observed within 3 (splenius) and 4 weeks (trapezius). For most patients the recovery dynamics lasted 4-6 weeks. A minority of patients did not show any improvement after 6 weeks. The present study shows that the dynamics of pressure pain due to whiplash injury can be quantified by means of PC-interactive pressure algesimetry. Our results confirm the clinical experience that the acute post-traumatic cervical syndrome normally subsides within weeks.

scholarly journals Altered Perception of Distorted Visual Feedback Occurs Soon After Whiplash Injury: An Experimental Study of Central Nervous System Processing

2012 ◽  
Vol 5;15 (5;9) ◽  
pp. 405-413
Author(s):  
Jo Nijs
Keyword(s):  
Central Nervous System ◽  
Experimental Study ◽  
Nervous System ◽  
Medical Care ◽  
Visual Feedback ◽  
Whiplash Injury ◽  
Acute Stage ◽  
Red Cross ◽  
Healthy Controls ◽  
Prospective Longitudinal

Background: Sensory and motor system dysfunctions have been documented in a proportion of patients with acute whiplash associated disorders (WAD). Sensorimotor incongruence may occur and hence, may explain pain and other sensations in the acute stage after the trauma. Objectives: The present study aimed at 1) evaluating whether a visually mediated incongruence between sensory feedback and motor output increases symptoms and triggers additional sensations in patients with acute WAD, 2) investigating whether the pattern of sensations in response to sensorimotor incongruence differs among patients suffering from acute and chronic WAD, and healthy controls. Study Design: Experimental study. Setting: Patients with acute WAD were recruited within one month after whiplash injury via the emergency department of a local Red Cross medical care unit, the Antwerp University Hospital, and through primary care practices. Patients with chronic WAD were recruited through an advertisement on the World Wide Web and from the medical database of a local Red Cross medical care unit. Healthy controls were recruited from among the university college staff, family members, and acquaintances of the researchers. Methods: Thirty patients with acute WAD, 35 patients with chronic WAD, and 31 healthy persons were subjected to a coordination test. They performed congruent and incongruent arm movements while viewing a whiteboard or mirror. Results. Twenty-eight patients with acute WAD reported sensations such as pain, tightness, feeling of peculiarity, and tiredness at some stage of the test protocol. No significant differences in frequencies and intensities of sensations were found between the various test stages (P > .05). Significantly more sensations were reported during the incongruent mirror stage compared to the incongruent control stage (P < .05). The pattern in intensity of sensations across the congruent and incongruent stages was significantly different between the WAD groups and the control group. Limitations: The course and prognostic value of susceptibility to sensorimotor incongruence after an acute whiplash trauma are not yet clear from these results. A prospective longitudinal study with an expanded study population is needed to investigate if those with a lowered threshold to visually mediated sensorimotor incongruence in the acute stage are at risk to develop persistent pain and disability. Conclusion: Patients with acute WAD present an exacerbation of symptoms and additional sensations in response to visually mediated changes during action. These results indicate an altered perception of distorted visual feedback and suggest altered central sensorimotor nervous system processing in patients with acute WAD. Key words: Sensorimotor incongruence, visually mediated changes, whiplash, sensations, acute pain, chronic pain, altered central sensorimotor processing, central nervous system.

scholarly journals The Structure of the Causes of Primary Prosthetics of the Shoulder Joint

2021 ◽  
pp. 42-48
Author(s):  
S.S. Strafun ◽  
I.S. Zanko
Keyword(s):  
Shoulder Joint ◽  
General Structure ◽  
High Energy ◽  
Acute Injury ◽  
Clinical Group ◽  
Aseptic Necrosis ◽  
Traumatic Injuries ◽  
Female Patients ◽  
Number Of Patients ◽  
Post Traumatic

Relevance. Shoulder prosthetics is the method of choice in the treatment of patients with traumatic injuries that significantly impair joint function and are accompanied by prolonged pain. Objective: to investigate the main causes of injuries of the shoulder joint that led to its prosthetics. Materials and Methods. The clinical group consisted of 162 patients who underwent shoulder prosthetics in the Department of Microsurgery and Reconstructive Surgery of the Upper Limb of the SI “Institute of Traumatology and Orthopedics of NAMS of Ukraine”. There were 44.4% male and 55.5% female patients. The average age of male patients was 62±11.4 years; the average age of female patients was 66±10.1 years. The average period of seeking specialized medical care after an acute injury was 24±10.9 days and 50.6±81.1 months in patients with post-traumatic consequences. In most cases, patients underwent unipolar prosthetics of the shoulder joint (126 patients, 78.7%); 27 patients (15.6%) underwent reversible prosthetics and 9 (5.6%) – total prosthetics, respectively. Results. In most cases, shoulder prosthetics were performed in patients with acute (up to 3 weeks from the date of injury) and old fractures and fractures of the proximal epimetaphysis of the humerus – 35 (21.6%) and 48 (29.6%) patients, respectively. The number of patients with posttraumatic aseptic necrosis of the humeral head was 49 (30.2%) (p<0.005), which indicates a high frequency of complications after osteosynthesis etc. The number of patients with massive traumatic injuries of the tendons of the rotator cuff who needed shoulder prosthetics was 18 (11.1%) and with false joints – 12 (7.4%). Unipolar prosthesis systems predominated in the general structure of the prosthesis type (126 patients, 78.7%), since reversible and total prosthesis in Ukraine were registered not so long ago. Conclusions. The analysis of our observations showed that the causes of shoulder prosthetics are severe injuries that occur with high-energy injuries (101 patients, 62.3%) and post-traumatic aseptic necrosis (49 patients, 30.2%). Acute and old fractures and fractures of the proximal metaepiphysis of the humerus are one of the most common injuries according to the analysis (35 patients, 21.6% and 48 patients, 29.6%), and their number and complexity continues to increase with age. Understanding the etiological factors that led to shoulder endoprosthetics makes it possible to predict long-term functional results and work to reduce the number of such patients.

scholarly journals Different experimental multiple trauma models induce comparable inflammation and organ injury

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Borna Relja ◽  
Bing Yang ◽  
Katrin Bundkirchen ◽  
Baolin Xu ◽  
Kernt Köhler ◽  
...  
Keyword(s):  
Inflammatory Response ◽  
Multiple Trauma ◽  
Inflammatory Cells ◽  
Organ Damage ◽  
Organ Injury ◽  
Local Inflammatory Response ◽  
Healthy Control ◽  
Post Traumatic ◽  
Tissue Trauma ◽  
Trauma Group

AbstractMultiple injuries appear to be a decisive factor for experimental polytrauma. Therefore, our aim was to compare the inflammatory response and organ damage of five different monotrauma with three multiple trauma models. For this, mice were randomly assigned to 10 groups: Healthy control (Ctrl), Sham, hemorrhagic shock (HS), thoracic trauma (TxT), osteotomy with external fixation (Fx), bilateral soft tissue trauma (bsTT) or laparotomy (Lap); polytrauma I (PT I, TxT + HS + Fx), PT II (TxT + HS + Fx + Lap) and one multi-trauma group (MT, TxT + HS + bsTT + Lap). The inflammatory response and organ damage were quantified at 6 h by analyses of IL-6, IL-1β, IL-10, CXCL1, SAA1, HMGB1 and organ injury. Systemic IL-6 increased in all mono and multiple trauma groups, while CXCL1 increased only in HS, PT I, PT II and MT vs. control. Local inflammatory response was most prominent in HS, PT I, PT II and MT in the liver. Infiltration of inflammatory cells into lung and liver was significant in all multiple trauma groups vs. controls. Hepatic and pulmonary injury was prominent in HS, PT I, PT II and MT groups. These experimental multiple trauma models closely mimic the early post-traumatic inflammatory response in human. Though, the choice of read-out parameters is very important for therapeutic immune modulatory approaches.

scholarly journals Surgical excision of post-traumatic myositis ossificans of the adductor longus in a football player

2020 ◽  
Vol 13 (3) ◽  
pp. e233504
Author(s):  
Gijs Herman Joseph de Smet ◽  
Steven E Buijk ◽  
Adam Weir
Keyword(s):  
Conservative Treatment ◽  
Myositis Ossificans ◽  
Surgical Excision ◽  
Football Player ◽  
Acute Injury ◽  
Background Information ◽  
Activity Levels ◽  
Longus Muscle ◽  
Post Traumatic ◽  
Adductor Longus

A football player was diagnosed with myositis ossificans of his right adductor longus muscle after an acute injury. Conservative treatment failed and 1 year after the initial trauma the patient underwent surgical excision of a large ossification. Seven months postoperatively, the patient was fully recovered and returned to his preinjury activity levels. We present our approach to this case and discuss our considerations, referring to background information about this rare disease.

Elevated Extracellular Levels of Granzymes in Patients with Scrub Typhus

2021 ◽  
Author(s):  
Joo-Hee Hwang ◽  
Jeong-Hwan Hwang ◽  
Chang-Seop Lee
Keyword(s):  
Cytotoxic T Lymphocytes ◽  
Scrub Typhus ◽  
Elevated Liver Enzyme ◽  
Cell Activity ◽  
Acute Stage ◽  
Cytotoxic T Cell ◽  
Orientia Tsutsugamushi ◽  
Treatment Results ◽  
Delayed Treatment ◽  
Healthy Control

Scrub typhus is an acute febrile disease caused by Orientia tsutsugamushi, which is transmitted through chigger mites. Delayed treatment results in various complications and, in severe cases, death. Granzymes are secreted by cytotoxic T lymphocytes or natural killer cells and are known to play an important role in controlling intracellular pathogens. To date, few studies have been done on granzymes in patients with scrub typhus. In this study, granzymes A and B showed a significant increase during the acute stage of scrub typhus compared with healthy control subjects, and decreased sharply after treatment. In addition, granzymes A and B were significantly high in the moderately elevated liver enzyme group. In conclusion, it appears that the host during the acute phase of scrub typhus increases cytotoxic T-cell activity to control infection.

scholarly journals Sex differences in objective measures of sleep in post-traumatic stress disorder and healthy control subjects

2013 ◽  
Vol 22 (6) ◽  
pp. 679-687 ◽  
Author(s):  
Anne Richards ◽  
Thomas J. Metzler ◽  
Leslie M. Ruoff ◽  
Sabra S. Inslicht ◽  
Madhu Rao ◽  
...  
Keyword(s):  
Sex Differences ◽  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Stress Disorder ◽  
Objective Measures ◽  
Post Traumatic Stress ◽  
Control Subjects ◽  
Healthy Control ◽  
Post Traumatic
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