scholarly journals Effects of 5-HT uptake inhibitors, agonists and antagonists on the burying of harmless objects by mice; a putative test for anxiolytic agents

1991 ◽  
Vol 104 (1) ◽  
pp. 105-112 ◽  
Author(s):  
K. Njung'e ◽  
S.L. Handley
Keyword(s):  
Uptake Inhibitors ◽  
5 Ht Uptake

The Antidepressant Effects of 5-HT Uptake Inhibitors

1989 ◽  
Vol 155 (S8) ◽  
pp. 32-40 ◽  
Author(s):  
Anna Åberg-Wistedt
Keyword(s):  
Side Effects ◽  
Clinical Studies ◽  
Human Platelets ◽  
Obsessive Compulsive ◽  
Functional Roles ◽  
Compulsive Disorder ◽  
Uptake Inhibitors ◽  
Antidepressant Effects ◽  
5 Ht Uptake ◽  
Review Reports

The functional roles of monaminergic transmitters in depression have been widely studied during the past decade. Data from that research suggest that lower levels of the 5-HT metabolite, 5-HIAA, in the cerebrospinal fluid; 5-HT uptake in human platelets; and platelets [3H]-imipramine binding sites occur in depressed patients. In recent years several potent and selective 5-HT uptake inhibitors have become available for clinical studies. The first shown to have antidepressant effects, zimelidine, was followed by similar compounds such as femoxetine, fluvoxamine, Citalopram, indalpine, fluoxetine, paroxetine, and sertraline. The effectiveness of serotonin inhibitors in treating other disorders, such as obsessive–compulsive disorder, anxiety, and panic disorder, has also been demonstrated. This review reports the data from clinical studies with these agents. The 5-HT uptake inhibitors are devoid of anticholinergic properties and have not produced weight gain or sedative side-effects, but may have another profile of side-effects. Headache, nausea, and vomiting have been reported, however.

scholarly journals Endogenous 5-HT outflow from chicken aorta by 5-HT uptake inhibitors and amphetamine derivatives

2016 ◽  
Vol 78 (1) ◽  
pp. 71-76 ◽  
Author(s):  
Dugar DELGERMURUN ◽  
Shigeo ITO ◽  
Toshio OHTA ◽  
Soichiro YAMAGUCHI ◽  
Ken-ichi OTSUGURO
Keyword(s):  
Uptake Inhibitors ◽  
5 Ht Uptake ◽  
Amphetamine Derivatives

Effect of washing procedure on platelets pretreated by 5-HT uptake inhibitors

1997 ◽  
Vol 42 (1) ◽  
pp. 252S-253S
Author(s):  
T. Kasahara ◽  
E. Nagata ◽  
J. Ishigooka ◽  
M. Murasaki ◽  
S. Miura
Keyword(s):  
Uptake Inhibitors ◽  
5 Ht Uptake
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