Deproteinized Bovine Bone Used as an Adjunct to Guided Bone Augmentation: An Experimental Study in the Rat

2001 ◽  
Vol 3 (3) ◽  
pp. 156-165 ◽  
Author(s):  
Andreas Stavropoulos ◽  
Lambros Kostopoulos ◽  
Nicolaos Mardas ◽  
Jens Randel Nyengaard ◽  
Thorkild Karring
Keyword(s):  
Experimental Study ◽  
Bovine Bone ◽  
Bone Augmentation ◽  
Deproteinized Bovine Bone

Deproteinized bovine bone mineral in marginal defects at implants installed immediately into extraction sockets: an experimental study in dogs

2011 ◽  
Vol 23 (1) ◽  
pp. 106-112 ◽  
Author(s):  
Marco Caneva ◽  
Daniele Botticelli ◽  
Fabio Pantani ◽  
Gabriele M. Baffone ◽  
Idelmo Garcia Rangel Jr ◽  
...  
Keyword(s):  
Experimental Study ◽  
Bone Mineral ◽  
Bovine Bone ◽  
Bovine Bone Mineral ◽  
Deproteinized Bovine Bone Mineral ◽  
Deproteinized Bovine Bone

Vertical bone augmentation with simultaneous implantation using deproteinized bovine bone block functionalized with a slow delivery of BMP‐2

2020 ◽  
Vol 31 (3) ◽  
pp. 215-228 ◽  
Author(s):  
Fei Teng ◽  
Lingfei Wei ◽  
Dedong Yu ◽  
Liquan Deng ◽  
Yuanna Zheng ◽  
...  
Keyword(s):  
Bone Block ◽  
Bovine Bone ◽  
Bone Augmentation ◽  
Deproteinized Bovine Bone

Deproteinized bovine bone mineral particles and osseointegration of implants without primary bone contact: an experimental study in dogs

2013 ◽  
Vol 25 (3) ◽  
pp. 296-303
Author(s):  
Stefano Sivolella ◽  
Eriberto Bressan ◽  
Luiz A. Salata ◽  
Maria E. Quiñones ◽  
Niklaus P. Lang ◽  
...  
Keyword(s):  
Experimental Study ◽  
Bone Mineral ◽  
Bovine Bone ◽  
Bone Contact ◽  
Mineral Particles ◽  
Primary Bone ◽  
Bovine Bone Mineral ◽  
Deproteinized Bovine Bone Mineral ◽  
Deproteinized Bovine Bone

scholarly journals Minocycline Hydrochloride as a Potential Adjuvant to Improve Osteoconductive and Osteoinductive Properties of Bone Substitutes in an Extra-Skeletal Bone Augmentation Model: Preliminary Observations in Rats

2021 ◽  
Vol 2 (01) ◽  
pp. 1-5
Author(s):  
Bob Biewer ◽  
Dorien Van Hede ◽  
Eric Rompen ◽  
Michel Mittelbronn ◽  
Pascale Quatresooz ◽  
...  
Keyword(s):  
Bone Substitutes ◽  
The Other ◽  
Bovine Bone ◽  
Bone Augmentation ◽  
Control Groups ◽  
Minocycline Hydrochloride ◽  
Skeletal Bone ◽  
Bovine Bone Mineral ◽  
Deproteinized Bovine Bone Mineral ◽  
Deproteinized Bovine Bone

Abstract Objectives The present study was performed to determine if minocycline HCl could influence the behavior of deproteinized bovine bone mineral (DBBM) and bioactive glass (BG) particles when used as filler material for new bone generation in a guided bone augmentation model. Materials and Methods Two occlusive titanium caps were placed on the rat calvaria. One filled with BG particles, the second with DBBM particles, both previously mixed with blood (control). In minocycline HCl loaded groups (experimental), grafts were additionally placed into a minocycline solution. Samples were harvested after 4, 8, and 16 weeks. Half of the samples were embedded in methylmethacrylate for undecalcified histology and the other half was fixed, decalcified, and embedded in paraffin for classical histologic analysis. Results The control groups highlighted osteoconductive and osteoinductive responses associated to BG particles, as well as an osteoconductive reaction, in DBBM sections. The addition of minocycline HCl to BG particles had no measurable influence on the result. In minocycline HCl loaded DBBM sections; however, areas of spontaneous ossification could be observed after 8 and 16 weeks. Conclusion Our observations suggest that minocycline HCl may add some osteoinductive properties to DBBM within the limitations of this study design. Further investigations are needed to refine the present results.

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