scholarly journals Binocular visual function and fixational control in patients with macular disease: A review

2021 ◽  
Author(s):  
Irina Sverdlichenko ◽  
Mark S Mandelcorn ◽  
Galia Issashar Leibovitzh ◽  
Efrem D Mandelcorn ◽  
Samuel N Markowitz ◽  
...  
Keyword(s):  
Visual Function ◽  
Macular Disease

scholarly journals The effects of a lutein-based supplement on objective and subjective measures of retinal and visual function in eyes with age-related maculopathy – a randomised controlled trial

2012 ◽  
Vol 109 (11) ◽  
pp. 2008-2014 ◽  
Author(s):  
Emma J. Berrow ◽  
Hannah E. Bartlett ◽  
Frank Eperjesi ◽  
Jonathan M. Gibson
Keyword(s):  
Visual Function ◽  
Controlled Trial ◽  
Treated Group ◽  
Macular Disease ◽  
Significance Level ◽  
Age Related ◽  
Clinically Significant ◽  
Randomised Controlled ◽  
Oral Supplement ◽  
Reduced Risk

Lutein and zeaxanthin are lipid-soluble antioxidants found within the macula region of the retina. Links have been suggested between increased levels of these carotenoids and reduced risk for age-related macular disease (ARMD). Therefore, the effect of lutein-based supplementation on retinal and visual function in people with early stages of ARMD (age-related maculopathy, ARM) was assessed using multi-focal electroretinography (mfERG), contrast sensitivity and distance visual acuity. A total of fourteen participants were randomly allocated to either receive a lutein-based oral supplement (treated group) or no supplement (non-treated group). There were eight participants aged between 56 and 81 years (65·50 (sd 9·27) years) in the treated group and six participants aged between 61 and 83 years (69·67 (sd 7·52) years) in the non-treated group. Sample sizes provided 80 % power at the 5 % significance level. Participants attended for three visits (0, 20 and 40 weeks). At 60 weeks, the treated group attended a fourth visit following 20 weeks of supplement withdrawal. No changes were seen between the treated and non-treated groups during supplementation. Although not clinically significant, mfERG ring 3 N2 latency (P= 0·041) and ring 4 P1 latency (P= 0·016) increased, and a trend for reduction of mfERG amplitudes was observed in rings 1, 3 and 4 on supplement withdrawal. The statistically significant increase in mfERG latencies and the trend for reduced mfERG amplitudes on withdrawal are encouraging and may suggest a potentially beneficial effect of lutein-based supplementation in ARM-affected eyes.

scholarly journals Macular Pigment, Visual Function, and Macular Disease among Subjects with Alzheimer's Disease: An Exploratory Study

2014 ◽  
Vol 42 (4) ◽  
pp. 1191-1202 ◽  
Author(s):  
John M. Nolan ◽  
Ekaterina Loskutova ◽  
Alan N. Howard ◽  
Rachel Moran ◽  
Riona Mulcahy ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Visual Function ◽  
Exploratory Study ◽  
Macular Pigment ◽  
Macular Disease

Contrast sensitivity function in patients with macular disease and good visual acuity

2021 ◽  
pp. bjophthalmol-2020-318494
Author(s):  
Karen M Wai ◽  
Filippos Vingopoulos ◽  
Itika Garg ◽  
Megan Kasetty ◽  
Rebecca F Silverman ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Macular Degeneration ◽  
Contrast Sensitivity ◽  
Visual Function ◽  
Sensitivity Function ◽  
Age Related Macular Degeneration ◽  
Macular Disease ◽  
Age Related ◽  
Spatial Frequencies ◽  
Healthy Control

IntroductionContrast sensitivity function (CSF) may better estimate a patient’s visual function compared with visual acuity (VA). Our study evaluates the quick CSF (qCSF) method to measure visual function in eyes with macular disease and good letter acuity.MethodsPatients with maculopathies (retinal vein occlusion, macula-off retinal detachment, dry age-related macular degeneration and wet age-related macular degeneration) and good letter acuity (VA ≥20/30) were included. The qCSF method uses an intelligent algorithm to measure CSF across multiple spatial frequencies. All maculopathy eyes combined and individual macular disease groups were compared with healthy control eyes. Main outcomes included area under the log CSF (AULCSF) and six CS thresholds ranging from 1 cycle per degree (cpd) to 18 cpd.Results151 eyes with maculopathy and 93 control eyes with VA ≥20/30 were included. The presence of a maculopathy was associated with significant reduction in AULCSF (β: −0.174; p<0.001) and CS thresholds at all spatial frequencies except for 18 cpd (β: −0.094 to −0.200 log CS, all p<0.01) compared with controls. Reductions in CS thresholds were most notable at low and intermediate spatial frequencies (1.5 cpd, 3 cpd and 6 cpd).ConclusionCSF measured with the qCSF active learning method was found to be significantly reduced in eyes affected by macular disease despite good VA compared with healthy control eyes. The qCSF method is a promising clinical tool to quantify subtle visual deficits that may otherwise go unrecognised by current testing methods.

Cognitive competence at the onset of West syndrome: correlation with EEG patterns and visual function

2005 ◽  
Vol 47 (11) ◽  
pp. 760 ◽  
Author(s):  
Teresa Randò ◽  
Giovanni Baranello ◽  
Daniela Ricci ◽  
Andrea Guzzetta ◽  
Francesca Tinelli ◽  
...  
Keyword(s):  
Visual Function ◽  
West Syndrome ◽  
Cognitive Competence

Prevention of Visual Function in the Direct Surgery of Paraclinoid Aneurysms

2014 ◽  
Vol 75 (S 02) ◽  
Author(s):  
Yutaka Mine ◽  
H. Ishimori ◽  
H. Murakami ◽  
T. Horikoshi ◽  
M. Ishihara
Keyword(s):  
Visual Function ◽  
Paraclinoid Aneurysms

Diagnosis of visual function in patients with loss of central vision

2019 ◽  
pp. 225-228
Author(s):  
A.P. Ermolaev ◽  
◽  
V.P. Erichev ◽  
A.A. Antonov ◽  
Y.V. Levitsky ◽  
...  
Keyword(s):  
Visual Function ◽  
Central Vision
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