Residual risk of transfusion‐transmitted hepatitis B virus ( TT‐HBV ) infection by NAT ‐screened blood components: A review of observed versus modeled infectivity from donors with window period and occult HBV infections

Transfusion ◽  
2021 ◽  
Author(s):  
Nico Lelie ◽  
Michael Busch ◽  
Steve Kleinman
Transfusion ◽  
2012 ◽  
Vol 53 (7) ◽  
pp. 1393-1404 ◽  
Author(s):  
Rikizo Taira ◽  
Masahiro Satake ◽  
Shun'ya Momose ◽  
Satoru Hino ◽  
Yoshiharu Suzuki ◽  
...  

Vox Sanguinis ◽  
2008 ◽  
Vol 95 (3) ◽  
pp. 174-180 ◽  
Author(s):  
K. Satoh ◽  
A. Iwata-Takakura ◽  
A. Yoshikawa ◽  
Y. Gotanda ◽  
T. Tanaka ◽  
...  

2011 ◽  
Vol 35 (8-9) ◽  
pp. 554-559 ◽  
Author(s):  
M.K. Arababadi ◽  
A.A. Pourfathollah ◽  
A. Jafarzadeh ◽  
G. Hassanshahi ◽  
M. Salehi ◽  
...  

2016 ◽  
Vol 35 (2) ◽  
pp. 47
Author(s):  
Somying Ngamurulert ◽  
Isaya Janwithayanuchit ◽  
Sumonrat Chuwongwattana ◽  
Suda Louisirirotchanakul ◽  
Prasert Auewarakul

Objective: To investigate the prevalence of hepatitis B virus (HBV) infection and to diagnose an occult HBV infection in healthy Thai subjects after implementation of the expanded program on immunization (EPI) in newborns.Material and Method: The detection of HBsAg, anti-HBs and anti-HBc was done from serum samples of 5,886 healthy first year students from Huachiew Chalermprakiet University collected between 2009-2011 by immunochro-matography rapid assay (Alcon, USA). In case of only anti-HBc positive, the results were confirmed with chemiluminescence enzyme immunoassay (EIA) method and then they were investigated further for HBV occult infection by nested polymerase chain reaction technique.Results: A total of 78% (4,593/5,886) healthy first year students who had been vaccinated with HBV vaccine since birth were found to have no HBV markers, while 18.4% (1,083/5,886) had only anti-HBs. The prevalence of infection was 3.6% (210/5,886). Identification of patterns of HBV infection among the 210 infected subjects found that (1) Immuned due to past infection was 61.9% (130/210) (2) Infected with hepatitis B virus was 38.1% (80/120). The prevalence of both HBsAg and anti-HBc was 28.6% (60/210), while the prevalences of HBsAg and Anti-HBc alone were 3.8% (8/210) and 5.7% (12/210), respectively. Anti-HBc alone group was repeated with chemiluminescence EIA and HBV DNA was negative.Conclusion: The prevalence of HBV infection was 3.6% (210/5,886), however, seropositive rate of HBV infection was 1.4% (80/5,886). Most antibodies from vaccination had substantially declined to the point that it was undetectable. Therefore, the overall study showed an effective implementation of EPI in newborns. 


2005 ◽  
Vol 79 (24) ◽  
pp. 15578-15581 ◽  
Author(s):  
E. Rodríguez-Íñigo ◽  
J. Bartolomé ◽  
N. Ortiz-Movilla ◽  
C. Platero ◽  
J. M. López-Alcorocho ◽  
...  

ABSTRACT In this work, we have shown that hepatitis C virus (HCV) and hepatitis B virus (HBV) can coexist in the same hepatocyte using double fluorescent in situ hybridization in liver biopsy samples from patients with chronic HCV infection with occult HBV infection. Digital image analysis of hybridization signals showed that the HBV DNA levels in coinfected hepatocytes were lower than those in cells infected only with HBV. This finding supports the hypothesis of inhibition of HBV replication by HCV. Furthermore, HCV RNA levels were lower in coinfected cells than in cells infected only with HCV, suggesting that HBV may also inhibit HCV replication.


2004 ◽  
Vol 126 (1) ◽  
pp. 102-110 ◽  
Author(s):  
Teresa Pollicino ◽  
Giovanni Squadrito ◽  
Giovanni Cerenzia ◽  
Irene Cacciola ◽  
Giuseppina Raffa ◽  
...  

2009 ◽  
Vol 13 ◽  
pp. S78
Author(s):  
Zheng-lin Wu ◽  
Jian Liu ◽  
Xiao-qiang Zhong ◽  
Guang-cheng Lin ◽  
Xue-dong Lu

Sign in / Sign up

Export Citation Format

Share Document