Constitutive Model of Biodegradable Non-Linear Polymeric Materials for Applications in the Biomedical Field

2007 ◽  
Author(s):  
Joao S. Soares ◽  
James E. Moore ◽  
Kumbakonam R. Rajagopal
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Constitutive Model ◽  
Biodegradable Polymers ◽  
Biomedical Application ◽  
Polymeric Materials ◽  
Local Drug Delivery ◽  
Engineering Applications ◽  
Non Linear ◽  
Biomedical Field

Synthetic biodegradable polymers have seen a dramatic increase in their availability and utilization over the last few decades. The first reported biomedical application of biodegradable polymers was during the 70s in biodegradable sutures and to date, it remains as the most widespread usage of this family of materials. Biodegradable polymers have also been proven to be effective carriers in local drug delivery therapies and are widely used as a primary constituent of scaffolds in tissue engineering applications.

scholarly journals Biomedical application of photo-crosslinked gelatin hydrogels

2021 ◽  
Vol 3 (1) ◽  
Author(s):  
Lei Xiang ◽  
Wenguo Cui
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Biomedical Application ◽  
Biomedical Field ◽  
Or Gene ◽  
Tunable Mechanical Properties ◽  
Bio Compatibility ◽  
Regeneration Of Bone ◽  
Development Prospects

Abstract During the past decades, photo-crosslinked gelatin hydrogel (methacrylated gelatin, GelMA) has gained a lot of attention due to its remarkable application in the biomedical field. It has been widely used in cell transplantation, cell culture and drug delivery, based on its crosslinking to form hydrogels with tunable mechanical properties and excellent bio-compatibility when exposed to light irradiation to mimic the micro-environment of native extracellular matrix (ECM). Because of its unique biofunctionality and mechanical tenability, it has also been widely applied in the repair and regeneration of bone, heart, cornea, epidermal tissue, cartilage, vascular, peripheral nerve, oral mucosa, and skeletal muscle et al. The purpose of this review is to summarize the recent application of GelMA in drug delivery and tissue engineering field. Moreover, this review article will briefly introduce both the development of GelMA and the characterization of GelMA. Finally, we discuss the challenges and future development prospects of GelMA as a tissue engineering material and drug or gene delivery carrier, hoping to contribute to accelerating the development of GelMA in the biomedical field. Graphical abstract

Hydrogels as Antibacterial Biomaterials

2018 ◽  
Vol 24 (8) ◽  
pp. 843-854 ◽  
Author(s):  
Weiguo Xu ◽  
Shujun Dong ◽  
Yuping Han ◽  
Shuqiang Li ◽  
Yang Liu
Keyword(s):  
Mechanical Properties ◽  
Drug Delivery ◽  
Tissue Engineering ◽  
Water Content ◽  
Oxygen Permeability ◽  
Structural Diversity ◽  
High Water ◽  
Clinical Applications ◽  
High Water Content ◽  
Biomedical Field

Hydrogels, as a class of materials for tissue engineering and drug delivery, have high water content and solid-like mechanical properties. Currently, hydrogels with an antibacterial function are a research hotspot in biomedical field. Many advanced antibacterial hydrogels have been developed, each possessing unique qualities, namely high water swellability, high oxygen permeability, improved biocompatibility, ease of loading and releasing drugs and structural diversity. In this article, an overview is provided on the preparation and applications of various antibacterial hydrogels. Furthermore, the prospects in biomedical researches and clinical applications are predicted.

Intrinsic porosity of calcium phosphate cements and its significance for drug delivery and tissue engineering applications

2009 ◽  
Vol 5 (7) ◽  
pp. 2752-2762 ◽  
Author(s):  
M. Espanol ◽  
R.A. Perez ◽  
E.B. Montufar ◽  
C. Marichal ◽  
A. Sacco ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Calcium Phosphate ◽  
Engineering Applications ◽  
Calcium Phosphate Cements

New core-shell hydroxyapatite/Gum-Acacia nanocomposites for drug delivery and tissue engineering applications

2018 ◽  
Vol 92 ◽  
pp. 685-693 ◽  
Author(s):  
Varun Prasath Padmanabhan ◽  
Ravichandran Kulandaivelu ◽  
Sankara Narayanan T.S. Nellaiappan
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Core Shell ◽  
Engineering Applications ◽  
Gum Acacia

Aerogels for Biomedical Applications

2021 ◽  
pp. 23-42
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Regenerative Medicine ◽  
Bone Regeneration ◽  
Biomedical Applications ◽  
Implantable Devices ◽  
Strategic Development ◽  
The World ◽  
Biomedical Field ◽  
Materials Used

The researchers across the world are actively engaged in strategic development of new porous aerogel materials for possible application of these extraordinary materials in the biomedical field. Due to their excellent porosity and established biocompatibility, aerogels are now emerging as viable solutions for drug delivery and other biomedical applications. This chapter aims to cover the diverse aerogel materials used across the globe for different biomedical applications including drug delivery, implantable devices, regenerative medicine encompassing tissue engineering and bone regeneration, and biosensing.

scholarly journals Ciprofloxacin-loaded polymeric nanoparticles incorporated electrospun fibers for drug delivery in tissue engineering applications

2020 ◽  
Vol 10 (3) ◽  
pp. 706-720 ◽  
Author(s):  
Cemre Günday ◽  
Shivesh Anand ◽  
Hikmet Burcu Gencer ◽  
Sara Munafò ◽  
Lorenzo Moroni ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Polymeric Nanoparticles ◽  
Electrospun Fibers ◽  
Engineering Applications
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