scholarly journals Horizontal Gene Transfer and Assortative Recombination within the Acinetobacter baumannii Clinical Population Provide Genetic Diversity at the Single carO Gene, Encoding a Major Outer Membrane Protein Channel

2011 ◽  
Vol 193 (18) ◽  
pp. 4736-4748 ◽  
Author(s):  
M. A. Mussi ◽  
A. S. Limansky ◽  
V. Relling ◽  
P. Ravasi ◽  
A. Arakaki ◽  
...  
2005 ◽  
Vol 49 (12) ◽  
pp. 5172-5175 ◽  
Author(s):  
Maria del Mar Tomás ◽  
Alejandro Beceiro ◽  
Astrid Pérez ◽  
David Velasco ◽  
Rita Moure ◽  
...  

ABSTRACT We investigated a multiresistant strain of Acinetobacter baumannii isolated in our hospital. Analysis of the N-terminal peptide sequence of the outer membrane proteins (OMPs) purified from the strain allowed us to clone and sequence the nucleotides of the gene encoding the 33- to 36-kDa OMP associated with carbapenem resistance in A. baumannii


2010 ◽  
Vol 286 (7) ◽  
pp. 5484-5493 ◽  
Author(s):  
Thamarai K. Janganan ◽  
Li Zhang ◽  
Vassiliy N. Bavro ◽  
Dijana Matak-Vinkovic ◽  
Nelson P. Barrera ◽  
...  

1997 ◽  
Vol 179 (4) ◽  
pp. 1082-1089 ◽  
Author(s):  
J C Fenno ◽  
G W Wong ◽  
P M Hannam ◽  
K H Müller ◽  
W K Leung ◽  
...  

1988 ◽  
Vol 56 (10) ◽  
pp. 2709-2716 ◽  
Author(s):  
E J Hansen ◽  
F R Gonzales ◽  
N R Chamberlain ◽  
M V Norgard ◽  
E E Miller ◽  
...  

2000 ◽  
Vol 68 (12) ◽  
pp. 6554-6560 ◽  
Author(s):  
P. A. Sokol ◽  
P. Darling ◽  
S. Lewenza ◽  
C. R. Corbett ◽  
C. D. Kooi

ABSTRACT Ornibactins are linear hydroxamate siderophores produced byBurkholderia cepacia with peptide structures similar to that of pyoverdines produced by the fluorescent pseudomonads. The gene encoding the outer membrane receptor (orbA) was identified, sequenced, and demonstrated to have significant homology with hydroxamate receptors produced by other organisms. The orbAprecursor was predicted to be a protein with a molecular mass of 81 kDa. An orbA mutant was constructed and demonstrated to be unable to take up 59Fe-ornibactins or to grow in medium supplemented with ornibactins. Outer membrane protein profiles from the parent strain, K56-2, revealed an iron-regulated outer membrane protein of 78 kDa that was not detectable in the K56orbA::tp mutant. When this mutant harbored a plasmid containing the orbA gene, the 78-kDa protein was present in the outer membrane protein profiles and the mutant was able to utilize ornibactin to acquire iron. The orbA mutant was less virulent in a chronic respiratory infection model than the parent strain, indicating that ornibactin uptake and utilization are important in the pathogenesis of B. cepacia respiratory infections.


1999 ◽  
Vol 43 (4) ◽  
pp. 607-608 ◽  
Author(s):  
K. Gensberg ◽  
A. W. Smith ◽  
F. S. L. Brinkman ◽  
R. E. W. Hancock

Sign in / Sign up

Export Citation Format

Share Document