scholarly journals Increased Incidence of Invasive Haemophilus influenzae Disease Driven by Non-Type B Isolates in Ontario, Canada, 2014 to 2018

2021 ◽  
Author(s):  
Lisa R. McTaggart ◽  
Kirby Cronin ◽  
Chi Yon Seo ◽  
Sarah Wilson ◽  
Samir N. Patel ◽  
...  
Keyword(s):  
Haemophilus Influenzae ◽  
World Health ◽  
Type B ◽  
Content Type ◽  
Vaccination Programs ◽  
The World ◽  
Life Threatening ◽  
Low Incidence ◽  
Serotype B ◽  
Health Organization

H. influenzae can cause serious invasive, life-threatening disease and is considered 1 of 12 priority pathogens by the World Health Organization. Widespread vaccination against H. influenzae serotype b (Hib) has resulted in very low incidence of Hib in Ontario and other regions that have vaccination programs.

scholarly journals COVID-19 Vaccination Perception and Attitude among Healthcare Workers in Egypt

2021 ◽  
Vol 12 ◽  
pp. 215013272110133
Author(s):  
Samar Fares ◽  
Merihan M. Elmnyer ◽  
Shimaa Sabry Mohamed ◽  
Radwa Elsayed
Keyword(s):  
Healthcare Workers ◽  
Study Groups ◽  
World Health ◽  
Vaccine Hesitancy ◽  
Accurate Information ◽  
P Value ◽  
Major Barrier ◽  
Vaccination Programs ◽  
The World ◽  
Health Organization

Introduction COVID-19 pandemic has affected the whole world, especially the frontline worriers. To get shielded through this war, the world is racing to reach and manufacture COVID-19 vaccines. Vaccination hesitancy is one of the significant obstacles to global health. Objectives This study aimed to assess the perception and attitude of healthcare workers in Egypt toward COVID-19 vaccines, acknowledge the determinants of their attitude, and the factors that could increase the acceptance of the vaccine. Methods an observational web-based anonymous survey was conducted on 385 Egyptian healthcare workers in different governorates. The questionnaire-based on Vaccine Hesitancy Survey Questions of the World Health Organization was available in Arabic and English languages and was tested for reliability. Results Regarding vaccination decision, 51% of the participants were undecided, 28% refused, and 21% accepted vaccination. Reasons for vaccine acceptance mainly were risks of COVID-19 (93%), safety (57.5%), and effectiveness (56.25%) of the vaccine. Simultaneously, the reasons for vaccine hesitancy were the absence of enough clinical trials (92.4%) and fear of side effects of the vaccine (91.4%). The leading factor that could increase vaccination acceptance among the participants was to get sufficient and accurate information about the available vaccines. The participants revealed a high mean level of concern for COVID-19 vaccines’ safety (3.8 of 5) that differs significantly among the different study groups ( P-value .002). Conclusion Despite the COVID-19 pandemic, only approximately 21% of Egyptian healthcare workers in our study accepted the COVID-19 vaccination. Vaccine hesitancy represents a major barrier to implementing vaccination programs.

Comparativa de modelos multivariados basados en aprendizaje automático para la predicción del riesgo de diabetes en etapas tempranas

2021 ◽  
Author(s):  
◽  
Zayra Ramírez Gaytán
Keyword(s):  
World Health ◽  
Degenerative Diseases ◽  
Decision Tree Algorithm ◽  
Data Set ◽  
The World ◽  
Long Time ◽  
Life Threatening ◽  
Health Organization ◽  
Logistic Regression Algorithm ◽  
Asymptomatic Phase

Diabetes is one of the fastest-growing, life-threatening, chronic degenerative diseases. According to the World Health Organization (WHO), it has affected 422 million people worldwide in 2018. Approximately 50% of all people who suffer diabetes are not diagnosed due to the asymptomatic phase which usually lasts a long time. In this work, a data set of 520 instances has been used. The data set has been analyzed with the next three algorithms: logistic regression algorithm, decision trees and random forest. The results show that the decision tree algorithm had better performance with an AUC of 98%. Also, it was found the most common symptoms that a person with a risk of diabetes presents are polyuria, polydipsia and sudden weight loss.

scholarly journals COVID-19- or Tramadol-induced Seizure: A Differential Diagnosis in Young People

2020 ◽  
Vol 10 (4) ◽  
pp. 32009.1-32009.2
Author(s):  
Solmaz Nekoueifard ◽  
◽  
Mohammad Majidi ◽  
Keyword(s):  
Myocardial Infarction ◽  
Acute Kidney Injury ◽  
Differential Diagnosis ◽  
Acute Respiratory Distress Syndrome ◽  
Distress Syndrome ◽  
Kidney Injury ◽  
World Health ◽  
The World ◽  
Life Threatening ◽  
Health Organization

Coronavirus disease 2019 (COVID-19) was first declared in December 2019 from Wuhan, China [1, 2]. It then has been reported a pandemic in March 2020 by the World Health Organization [3]. Clinical features of COVID-19 are different from asymptomatic to mild to moderate symptoms, such as fever, headache, myalgia, sore throat, anosmia, cough, fatigue headache, hemoptysis, and dyspnea to the life-threatening complications, including shock, pneumonia, acute respiratory distress syndrome, myocarditis, myocardial infarction, acute kidney injury, multi-organ failure, and even death [1, 2].

scholarly journals Buruli Ulcer: Review of a Neglected Skin Mycobacterial Disease

2017 ◽  
Vol 56 (4) ◽  
Author(s):  
Jeannette Guarner
Keyword(s):  
Clinical Presentation ◽  
Oral Treatment ◽  
Buruli Ulcer ◽  
Mycobacterium Ulcerans ◽  
World Health ◽  
Tissue Necrosis ◽  
Content Type ◽  
Skin Nodule ◽  
The World ◽  
Health Organization

ABSTRACTBuruli ulcer is caused byMycobacterium ulcerans. This neglected disease occurs in scattered foci around the world, with a higher concentration of cases in West Africa. The mycobacteria produce mycolactones that cause tissue necrosis. The disease presents as a painless skin nodule that ulcerates as necrosis expands. Finding acid-fast bacilli in smears or histopathology, culturing the mycobacteria, and performingM. ulceransPCR in presumptive cases confirm the diagnosis. Medical treatment with oral rifampin and intramuscular streptomycin or oral treatment with rifampin plus clarithromycin for 8 weeks is supported by the World Health Organization. This review summarizes the epidemiology, pathogenesis, clinical presentation, diagnostic tests, and advances in treatment.

The Effect Of Fe Tablet Consumption On Hemoglobin (Hb) Increase In Pregnant Women: A Systematic Literature Review

2020 ◽  
Vol 6 (2) ◽  
pp. 8-13
Author(s):  
Admin midwiferia ◽  
Pratiwi Cahya Skania ◽  
Djaswadi Dasuki ◽  
Fitriana Siswi Utami
Keyword(s):  
Pregnant Women ◽  
Critical Appraisal ◽  
World Health ◽  
Exclusion Criteria ◽  
Iron Supplements ◽  
Level Increase ◽  
The World ◽  
Life Threatening ◽  
Health Organization ◽  
Selection Of

Anemia is still a problem in developing countries. The World Health Organization states that there are still more than 50 percent of women in the world suffering from anemia. anemia can cause life-threatening bleeding, miscarriage, low birth weight and premature birth. WHO defines anemia as a condition where the hemoglobin level is less than 11 mg / dL in the first and last trimester or 10.5 mg / dL in the second trimester or the hematocrit level is less than 37 percent. The study aim to determine the effect of Fe tablets consumption on hemoglobin (Hb) level increase in pregnant women and to find out the factors related to the compliance of pregnant women taking Fe tablets.  This Systematic Literature Publication and Science uses databases with the period 2008-2018. The selection of articles was based on the inclusion and exclusion criteria. The Appraisal study employed The Joanna Briggs Institute Critical Appraisal Tools. Taking Fe tablets is very influential in increasing levels of Hb in pregnant women who suffer from anemia. Effective iron supplements to reduce anemia in pregnancy. Support from family and closest people has an important role in increasing adherence to taking Fe tablets.

School Nurses on the Front Lines of Healthcare: Infectious Diseases Popularized in the News

2020 ◽  
Vol 35 (4) ◽  
pp. 212-216
Author(s):  
Lauren McNickle ◽  
Robert P. Olympia
Keyword(s):  
Infectious Diseases ◽  
School Nurses ◽  
World Health ◽  
Initial Assessment ◽  
Health Organizations ◽  
Public Health Organizations ◽  
The World ◽  
Control And Prevention ◽  
Life Threatening ◽  
Health Organization

School nurses may deal with students presenting with symptoms associated with infections popularized in the news. Although rare, the implications of missing or misdiagnosing these infections are potentially life-threatening and devastating. We present three students presenting with febrile illnesses associated with neurologic symptoms, a rash, and fatigue, focusing on the initial assessment and management of these students and their associated “hot topic” infection. The authors also discuss two public health organizations, Centers for Disease Control and Prevention (https://www.cdc.gov/) and the World Health Organization (https://www.who.int/), online references for the school nurse to research both emerging and common infectious diseases.

COVID-19 alters focus of cyberespionage

2020 ◽  
Keyword(s):  
Civil Society ◽  
World Health Organization ◽  
World Health ◽  
Research Institutions ◽  
Content Type ◽  
Pharmaceutical Firms ◽  
Civil Society Organisations ◽  
Multilateral Institutions ◽  
The World ◽  
Health Organization

Significance Calls by the UN and civil society organisations for a cyberspace ‘ceasefire’ have made little difference. Impacts Trust in multilateral institutions such as the World Health Organization will be undermined if they suffer cyberattacks. Post-pandemic, China is likely to experience a rise in cyber intrusions from upcoming cyber actors such as Vietnam. Although better prepared than research institutions, large pharmaceutical firms are not immune to cyberespionage.

scholarly journals Could it be Quetiapine-induced Peripartum Cardiomyopathy?

2013 ◽  
Vol 6 (1) ◽  
pp. 35-37
Author(s):  
Mandeep Kaler ◽  
Rameen Shakur ◽  
Hazel I Learner ◽  
Andrew Deaner ◽  
Richard J Howard
Keyword(s):  
World Health Organization ◽  
Interesting Case ◽  
Peripartum Cardiomyopathy ◽  
World Health ◽  
The World ◽  
Life Threatening ◽  
Life Threatening Complication ◽  
Health Organization

Peri-partum Cardiomyopathy (PPCM) is a rare and life threatening complication of pregnancy. There are only two cases registered with the World Health Organization of cases of cardiomyopathy in patients taking Quetiapine. Here we discuss an interesting case of potential Quetiapine induced cardiomyopathy.

scholarly journals Avibactam Restores the Susceptibility of Clinical Isolates of Stenotrophomonas maltophilia to Aztreonam

2017 ◽  
Vol 61 (10) ◽  
Author(s):  
Maria F. Mojica ◽  
Krisztina M. Papp-Wallace ◽  
Magdalena A. Taracila ◽  
Melissa D. Barnes ◽  
Joseph D. Rutter ◽  
...  
Keyword(s):  
Stenotrophomonas Maltophilia ◽  
Opportunistic Pathogen ◽  
Multidrug Resistant ◽  
World Health ◽  
Combination Therapies ◽  
Content Type ◽  
Medical Need ◽  
The World ◽  
Health Organization

ABSTRACT Stenotrophomonas maltophilia is an emerging opportunistic pathogen, classified by the World Health Organization as one of the leading multidrug-resistant organisms in hospital settings. The need to discover novel compounds and/or combination therapies for S. maltophilia is urgent. We demonstrate the in vitro efficacy of aztreonam-avibactam (ATM-AVI) against S. maltophilia and kinetically characterize the inhibition of the L2 β-lactamase by avibactam. ATM-AVI overcomes aztreonam resistance in selected clinical strains of S. maltophilia, addressing an unmet medical need.

scholarly journals Effect of SARS-CoV-2 Mutations on the Efficacy of Antibody Therapy and Response to Vaccines

Vaccines ◽  
2021 ◽  
Vol 9 (8) ◽  
pp. 914
Author(s):  
Ahmed Yaqinuddin ◽  
Areez Shafqat ◽  
Junaid Kashir ◽  
Khaled Alkattan
Keyword(s):  
Monoclonal Antibody ◽  
Protective Immunity ◽  
Antibody Therapy ◽  
Antiviral Drugs ◽  
World Health ◽  
Significant Morbidity ◽  
Vaccination Programs ◽  
The World ◽  
Feasible Option ◽  
Health Organization

SARS-CoV-2 causes severe acute respiratory syndrome, which has led to significant morbidity and mortality around the world. Since its emergence, extensive prophylactic and therapeutic countermeasures have been employed to successfully prevent the spread of COVID-19. Extensive work has been undertaken on using monoclonal antibody therapies, mass vaccination programs, and antiviral drugs to prevent and treat COVID-19. However, since antiviral drugs could take years to become widely available, immunotherapy and vaccines currently appear to be the most feasible option. In December 2020, the first vaccine against SARS-CoV-2 was approved by the World Health Organization (WHO) and, subsequently, many other vaccines were approved for use by different international regulators in different countries. Most monoclonal antibodies (mAbs) and vaccines target the SARS-CoV-2 surface spike (S) protein. Recently, mutant (or variant) SARS-CoV-2 strains with increased infectivity and virulence that evade protective host antibodies present either due to infection, antibody therapy, or vaccine administration have emerged. In this manuscript, we discuss the different monoclonal antibody and vaccine therapies available against COVID-19 and how the efficacy of these therapies is affected by the emergence of variants of SARS-CoV-2. We also discuss strategies that might help society cope with variants that could neutralize the effects of immunotherapy and escape the protective immunity conferred by vaccines.

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