scholarly journals Transient neonatal hypothyroidism secondary to postnatal maternal exposure to contrast medium

2019 ◽  
Vol 12 (10) ◽  
pp. e230854 ◽  
Author(s):  
Céline Themelin ◽  
Charlotte Pierron ◽  
Jean-Felix Calafat ◽  
Carine de Beaufort

We report a preterm breastfed infant who developed a transient hypothyroidism after his lactating mother had a CT scan with iodinated contrast medium, despite the advised 24 hours’ pause in breast feeding. The aetiological assessment did not show any other cause for this hypothyroidism. Transient neonatal hypothyroidism after the use of topical iodine is well known, but it has not been described as a complication of intravenous contrast medium administration to a lactating mother. This case highlights the possibility of transient neonatal hypothyroidism secondary to contrast medium exposure to a lactating mother. When imaging is needed in the lactating mother, a longer break in breast feeding might be needed to prevent transient hypothyroidism in the preterm infant.

Radiology ◽  
2008 ◽  
Vol 248 (1) ◽  
pp. 97-105 ◽  
Author(s):  
Shaun A. Nguyen ◽  
Pal Suranyi ◽  
James G. Ravenel ◽  
Patrick K. Randall ◽  
Peter B. Romano ◽  
...  

1990 ◽  
Vol 13 (1) ◽  
pp. 73-76 ◽  
Author(s):  
H. Shimura ◽  
K. Takazawa ◽  
T. Endo ◽  
M. Tawata ◽  
T. Onaya

2021 ◽  
Vol 8 (8) ◽  
pp. 146
Author(s):  
Federica Cagnasso ◽  
Barbara Bruno ◽  
Claudio Bellino ◽  
Antonio Borrelli ◽  
Ilaria Lippi ◽  
...  

Intravenous iodinated contrast (IVIC) medium is routinely administered to dogs. Scattered information exists regarding the serum biochemical or urinary profiles associated with the administration of IVIC in dogs. The aim of the study was to describe, compare, and discuss from the perspective of previous studies the alterations in serum biochemical and urinary parameters before (T0) and within one week (T1) of the IVIC administration during routine computed tomography (CT) scan evaluation of 22 dogs. Mature dogs presenting for CT scan evaluation for preoperative oncology staging/surgical planning were included. T1 evaluation was performed within one week of IVIC administration. Statistically significant differences in serum total protein, albumin, chloride, calcium, and phosphorus concentrations, urine protein to creatinine ratio, and urine specific gravity were found between T1 and T0. At T1, the serum creatinine concentration was within reference ranges in all dogs but one. An increase in the urine protein to creatinine ratio was observed in four samples, one of which was non-proteinuric at T0. Changes in biochemistry and urine parameters between T0 and T1 were not considered clinically significant.


Author(s):  
Hilal Sahin ◽  
Camilla Panico ◽  
Stephan Ursprung ◽  
Vittorio Simeon ◽  
Paolo Chiodini ◽  
...  

Abstract Objective To determine the accuracy of interpretation of a non-contrast MRI protocol in characterizing adnexal masses. Methods and materials Two hundred ninety-one patients (350 adnexal masses) who underwent gynecological MRI at our institution between the 1st of January 2008 and the 31st of December 2018 were reviewed. A random subset (102 patients with 121 masses) was chosen to evaluate the reproducibility and repeatability of readers’ assessments. Readers evaluated non-contrast MRI scans retrospectively, assigned a 5-point score for the risk of malignancy and gave a specific diagnosis. The reference standard for the diagnosis was histopathology or at least one-year imaging follow-up. Diagnostic accuracy of the non-contrast MRI score was calculated. Inter- and intra-reader agreement was analyzed with Cohen’s kappa statistics. Results There were 53/350 (15.1%) malignant lesions in the whole cohort and 20/121 (16.5%) malignant lesions in the random subset. Good agreement between readers was found for the non-contrast MRI score (к = 0.73, 95% confidence interval [CI] 0.58–0.86) whilst the intra-reader agreement was excellent (к = 0.81, 95% CI 0.70–0.88). The non-contrast MRI score value of ≥ 4 was associated with malignancy with a sensitivity of 84.9%, a specificity of 95.9%, an accuracy of 94.2% and a positive likelihood ratio of 21 (area under the receiver operating curve 0.93, 95% CI 0.90–0.96). Conclusion Adnexal mass characterization on MRI without the administration of contrast medium has a high accuracy and excellent inter- and intra-reader agreement. Our results suggest that non-contrast studies may offer a reasonable diagnostic alternative when the administration of intravenous contrast medium is not possible. Key Points • A non-contrast pelvic MRI protocol may allow the characterization of adnexal masses with high accuracy. • The non-contrast MRI score may be used in clinical practice for differentiating benign from malignant adnexal lesions when the lack of intravenous contrast medium precludes analysis with the O–RADS MRI score.


Radiology ◽  
2009 ◽  
Vol 253 (3) ◽  
pp. 870-878 ◽  
Author(s):  
Douglas B. Macha ◽  
Rendon C. Nelson ◽  
Laurens E. Howle ◽  
John W. Hollingsworth ◽  
Sebastian T. Schindera

Sign in / Sign up

Export Citation Format

Share Document