scholarly journals Perceived physical health in obsessive-compulsive disorder: a protocol for a systematic review and meta-analysis

BMJ Open ◽  
2019 ◽  
Vol 9 (6) ◽  
pp. e026261 ◽  
Author(s):  
Andrea Pozza ◽  
Fabio Ferretti ◽  
Anna Coluccia
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Health Status ◽  
Physical Health ◽  
Meta Analysis ◽  
Publication Date ◽  
Physical Health Status ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

IntroductionObsessive-compulsive disorder (OCD) is a mental health condition associated with severe impairment in a variety of quality of life domains, an increased physical health burden, and a higher risk of general medical conditions and mortality compared with the general population. While there is a large amount of literature on psychological quality of life, a systematic review of perceived physical health in OCD is lacking. A quantitative summary might suggest that policy makers also focus the evaluation on perceived physical health and develop new strategies also aimed at this outcome. The current paper presents a protocol for the first systematic review and meta-analysis aimed at summarising perceived physical health in OCD by specifically examining perceived physical health status, bodily pain and role limitations due to physical problems in patients with OCD compared with controls. The review will also investigate potential demographic and clinical moderators of perceived physical health status (age, gender, OCD severity, publication date, methodological quality).Methods and analysisA systematic review and meta-analysis will be conducted according to PRISMA guidelines. Studies will be included if using a clinical group with a current primary diagnosis of OCD established by international standardised criteria, if measuring perceived physical health status, and if using screened or community participants as controls. No publication date or language restriction will be applied. An online systematic search of electronic databases (Scopus, PubMed, PsycINFO, EMBASE, Cochrane Library), and examination of conference proceedings and theses/dissertations will be conducted by independent reviewers. Risk of bias will be assessed through the Newcastle-Ottawa Scale.Ethics and disseminationThe current review does not require ethics approval. The results will be disseminated through publications in peer-reviewed journals.PROSPERO registration number2018 CRD42018106194.

scholarly journals The Perception of Physical Health Status in Obsessive-Compulsive Disorder: A Systematic Review and Meta-Analysis

2019 ◽  
Vol 15 (1) ◽  
pp. 75-93 ◽  
Author(s):  
Andrea Pozza ◽  
Fabio Ferretti ◽  
Anna Coluccia
Keyword(s):  
Systematic Review ◽  
Health Status ◽  
Physical Health ◽  
Meta Analysis ◽  
Bodily Pain ◽  
Effect Sizes ◽  
Publication Date ◽  
Physical Health Status ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

Background: Physical Health Status is a neglected outcome in clinical practice with Obsessive-Compulsive Disorder (OCD) and a systematic review is lacking. Objective: The current study presents the first systematic review and meta-analysis summarizing the evidence on (a) perceived Physical Health Status, Bodily Pain and Role Limitations due to Physical Problems in patients with OCD compared with controls, (b) age, gender, severity of OCD symptoms, study publication date, study methodological quality as moderators of perceived Physical Health Status. Methods: Case-control studies were included if they (a) compared OCD patients with healthy/general population participants as controls, and (b) used validated self-report instruments. Two reviewers searched electronic databases, contacted corresponding authors, and examined reference lists/conference proceedings/theses. Results: Fourteen studies were included. A large significant negative effect size without publication bias showed that controls reported higher perceived Physical Health Status than patients with OCD. Medium and small effect sizes favouring controls emerged for Role Limitations due to Physical Problems and Bodily Pain, respectively. Higher age, females percentage, and publication date were associated with larger effect sizes; higher OCD severity and methodological quality were associated with smaller effect sizes. Conclusion: Perceived Physical Health should be evaluated and addressed by clinicians during treatment, particularly with older, female and less severe patients. Lifestyle interventions might be implemented.

Adult obsessive–compulsive disorder and quality of life outcomes: A systematic review and meta-analysis

2016 ◽  
Vol 22 ◽  
pp. 41-52 ◽  
Author(s):  
Anna Coluccia ◽  
Andrea Fagiolini ◽  
Fabio Ferretti ◽  
Andrea Pozza ◽  
Giulia Costoloni ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Obsessive Compulsive Disorder ◽  
Meta Analysis ◽  
Life Outcomes ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Quality Of Life Outcomes

scholarly journals Sexual dysfunction and satisfaction in obsessive compulsive disorder: protocol for a systematic review and meta-analysis

2020 ◽  
Vol 9 (1) ◽  
Author(s):  
Andrea Pozza ◽  
David Veale ◽  
Donatella Marazziti ◽  
Jaime Delgadillo ◽  
Umberto Albert ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Sexual Dysfunction ◽  
Obsessive Compulsive Disorder ◽  
Meta Analysis ◽  
Study Quality ◽  
Control Groups ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

Abstract Background Obsessive compulsive disorder (OCD) is a chronic mental health condition recognized as one of the most serious causes of disability and impaired quality of life. In the literature, there is no review about sexual dysfunction and satisfaction in OCD. The current paper presents the protocol for a systematic review and meta-analysis aimed to summarize data (1) comparing the presence of sexual dysfunction between groups with OCD and non-clinical groups, (2) investigating prevalence of each one of the sexual dysfunctions in patients with OCD, (3) comparing risk for sexual dysfunction in OCD groups with the prevalence in control groups, (4) comparing sexual satisfaction between OCD groups and non-clinical groups, and (5) investigating moderators of sexual dysfunction in OCD groups as compared with control groups. Gender, age, marital status, OCD symptom severity and subtypes, comorbid depressive disorders, comorbid anxiety disorders, concurrent psychiatric medications, comorbid general medical disease, and study quality will be investigated as moderators. Methods The protocol is reported according to PRISMA-P guidelines. The search will be conducted by independent reviewers during the second week of December 2019 by using electronic databases (Scopus, PubMed, EMBASE, PsycINFO, CINAHL, and the Cochrane Library), by contacting the authors of the included studies to identify further data, by examining the references of the included studies, and by handsearching conference proceedings and theses/doctoral dissertations. The study quality will be independently evaluated using the Newcastle-Ottawa Quality Assessment Scale. Random-effect meta-analyses will be computed. If there is insufficient data for a specific outcome, only a systematic review will be performed. Discussion This review may support clinical practice highlighting the importance of the assessment of sexuality in patients with OCD and suggesting the use of therapeutic strategies dedicated to sexuality in this clinical population with the aim of improving patients’ quality of life. Potential limitations will regard the heterogeneity of the studies in terms of the instruments used to assess sexual dysfunction/satisfaction and of the definitions used to conceptualize sexual dysfunction. Systematic review registration Prospero CRD42019132264

scholarly journals Mindfulness-based and acceptance-based programmes in the treatment of obsessive–compulsive disorder: a study protocol for a systematic review and meta-analysis

BMJ Open ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. e050329
Author(s):  
Johannes Julian Bürkle ◽  
Johannes Caspar Fendel ◽  
Stefan Schmidt
Keyword(s):  
Systematic Review ◽  
Depressive Symptoms ◽  
Obsessive Compulsive Disorder ◽  
Meta Analysis ◽  
Sensitivity Analyses ◽  
Secondary Outcome ◽  
Controlled Trials ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

IntroductionCognitive–behavioural therapy (CBT) with exposure and response prevention is the recommended standard for the treatment of obsessive–compulsive disorder (OCD). However, a high proportion of patients refuse this treatment, do not respond or relapse shortly after treatment. Growing evidence suggests that mindfulness-based and acceptance-based programmes (MABPs) are an effective option for the treatment of OCD. This systematic review and meta-analysis will examine the effectiveness of MABPs in treating OCD. We also aimed to explore potential moderators of the programmes’ effectiveness.Methods and analysisWe will systematically search MEDLINE, Embase, PsycINFO, PSYINDEX, Web of Science, CINAHL and Cochrane Register of Controlled Trials (no language restrictions) for studies that evaluate the effect of MABPs on patients with OCD. We will conduct backward and forward citation searches of included studies and relevant reviews and contact corresponding authors. The primary outcome will be pre-post intervention change in symptom severity. A secondary outcome will be change in depressive symptoms. Two reviewers will independently screen the records, extract the data and rate the methodological quality of the studies. We will include both controlled and uncontrolled trials. Randomised controlled trials will be meta-analysed, separately assessing between-group effects. A second meta-analysis will assess the within-group effect of all eligible studies. We will explore moderators and sources of heterogeneity such as the specific programme, study design, changes in depressive symptoms, hours of guided treatment, control condition and prior therapy (eg, CBT) using metaregression and subgroup analyses. We will perform sensitivity analyses using follow-up data. A narrative synthesis will also be pursued. We will use the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system to assess the quality of the evidence.Ethics and disseminationEthical approval is not required. Results will be published in peer-reviewed journals and presented at international conferences.

scholarly journals Factors that influence disease-specific quality of life or health status in patients with COPD: a systematic review and meta-analysis of Pearson correlations

2011 ◽  
Vol 20 (3) ◽  
pp. 257-268 ◽  
Author(s):  
Tsiligianni Ioanna ◽  
Janwillem Kocks ◽  
Nikolaos Tzanakis ◽  
Nikolaos Siafakas ◽  
Thys van der Molen
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Health Status ◽  
Meta Analysis ◽  
Pearson Correlations ◽  
Disease Specific

scholarly journals Factors Impacting Quality of Life in Patients With Klinefelter Syndrome: A Systematic Review with Narrative Synthesis and Meta-Analysis

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. A758-A758
Author(s):  
Brien Mehmet ◽  
Sofia V Llahana
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Social Relations ◽  
Meta Analysis ◽  
Autism Spectrum ◽  
Publication Date ◽  
Narrative Synthesis ◽  
Healthy Controls ◽  
Personal Beliefs

Abstract Objective: To identify how Klinefelter’s Syndrome affects patients’ quality of life (QoL) and to determine which subsections of QoL are affected guided by the WHOQOL100-tool as an overarching framework for QoL. To determine the effects and impact KS has on patients’ QoL when compared to the QoL of healthy controls and general population. DESIGN - Systematic review of studies reporting QoL factors among patients with KS which included narrative synthesis and thematic analysis of 17 studies and a meta-analysis of intelligence quotient (IQ) completed in 7 studies. QoL factors were reviewed based on the parameters of the WHOQOL-100: physical health, psychological, level of independence, social relations, environment, and religion/spirituality/personal beliefs. DATA SOURCES - Medline, Cochrane, Embase, Psychinfo, CINAHL, BASE and grey search from the reference lists of key publications. Eligibility Criteria: RCT’s, Cohort studies, cross sectional studies and Epidemiology studies involving patients with KS and reporting on QoL parameters. Only human studies published in English were considered with no limits for publication date. Results: Out of all studies included (n=1266), (87.5%) had suggested KS negatively affected the outcomes measures tested, where recorded (91.1%) of studies had small/medium/large effect sizes (Cohen’s d). Narrative synthesis suggests all subgroups of QoL excluding ‘environment’ and ‘spirituality/faith/personal beliefs’ were negatively impacted for patients with KS, whilst meta-analysis showed statistical significance (P <0.00001) which identified patients with KS having lower full-scale IQ compared to healthy controls. Psychological parameters were the most affected in this patient group, showing that patients with KS experienced greater social anxiety, distress during social interactions, self-esteem, self-injuries behaviours and symptoms or traits related to Autism spectrum. Conclusions: This review identifies the significant evidence supporting that QoL is reduced in patients with KS. There is a large spectrum of symptoms and no standard phenotype for KS suggesting that multiple facets of QoL are negatively impacted in these patients due to the complex nature of KS and the severity of symptoms and phenotype associated with KS. PROSPERO REGISTRATION NUMBER - CRD4202017343

PHYSICAL HEALTH STATUS OF PEOPLE AGED 60 YEARS AND OVER AT NURSING CLUBS IN DISTRICT 10, HO CHI MINH CITY

2021 ◽  
Vol 62 (6) ◽  
Author(s):  
Nguyen Manh Tri ◽  
Le Thi Tuong Van ◽  
Luong Thai Vinh ◽  
Vo Thi Ngoc Ha ◽  
Nguyen Thi Phuong ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Health Care ◽  
Health Status ◽  
Physical Health ◽  
The Elderly ◽  
Ho Chi Minh City ◽  
Average Score ◽  
Physical Health Status ◽  
Internal Factors

Background: The age of support and endurance against external and internal factors and agents is greatly less so that the need for health care including physical and mental training to improve the quality of life is essential especially the physical health of the elderly. Target:. Determination of physical health scores and associations of people aged 60 years and older at nursing clubs in District 10, Ho Chi Minh City, in 2019. Methods and materials: Descriptive cross-section study. People aged 60 years and over who have been training at nursing clubs living in District 10, Ho Chi Minh City were surveyed from September 2018 to October 2019. Results: The study showed an average score of 63.3 in ±17.3 points. In particular, physical activity: 61.0±23.1; physical limitations: 57.2±26.1; pain sensation: 68.2±22,2; general health: 59.6±14.9. Considering the relationship, as the age group increases, the mean score of the elderly's quality of life decreases statistically significantly in four áreas (p<0,05). Women have a statistically significantly higher mean score on quality of life than men (p<0,05). Conclusions: The results of the study are important information that informs the physical health status of elderly people aged 60 years and older, and suggests recommendations in improving the quality of physical health care of the elderly.

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