scholarly journals Perception and knowledge of human papillomavirus (HPV) vaccine for cervical cancer prevention among fully vaccinated female university students in the era of HPV vaccination: a cross-sectional study

BMJ Open ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. e047479
Author(s):  
Kah Teik Chew ◽  
Nirmala Kampan ◽  
Mohamad Nasir Shafiee

ObjectiveTo assess the perception and knowledge of cervical cancer prevention among fully vaccinated female university students in the era of human papillomavirus (HPV) vaccination.DesignCross-sectional using a validated questionnaire.SettingFace-to-face interview at a public university in Malaysia.Participants384 fully vaccinated female students were included in the study.ResultsThe total knowledge score in the questionnaire was 18 and was ranked according to score level into three groups: poor (score ≤5), moderate (score 6–10) and good (score ≥11). Mean score for knowledge of cervical cancer prevention was 8.24 (SD ±3.85), with 170 respondents (44.3%) scoring moderate knowledge level. The mean score for knowledge of HPV infection and its association with cervical cancer was 4.56±2.47, while the mean score for knowledge of HPV vaccination for cervical cancer prevention was 3.68 (SD ±1.98). A total of 186 (48.4%) respondents perceived that regular Pap smear was unnecessary after HPV vaccination. Respondents’ perceived seriousness and susceptibility of HPV infection correlated well with knowledge of cervical cancer prevention. Two main reasons for their acceptance of HPV vaccine were self-health awareness and free vaccination.ConclusionThe knowledge of HPV vaccination for cervical cancer prevention was average among vaccinated university students. Many of them had poor knowledge about Pap smear and did not consider regular Pap smear as an important cervical cancer screening tool following HPV vaccination. There is still a need for continued health education to improve the perception and knowledge about HPV infection and cervical cancer prevention among young adults in the community.

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 196s-196s ◽  
Author(s):  
A. Mburu ◽  
P. Itsura

Background: Primary prevention of cervical cancer with the introduction of the human papilloma virus (HPV) vaccines is the next generation means to reduction of the disease burden in developing countries. Sexually active adolescents have the highest rates of prevalent and incident HPV infection rates with over 50%–80% having infections within 12 months of initiating intercourse. From May 2012 to March 2013, through the Gardasil Access Program, Eldoret received 9600 vaccine doses and vaccinated over 3000 girls aged 9-14. Despite this, there is little information on the knowledge of cervical cancer among adolescents and their amenability to accepting cervical cancer prevention strategies. Aim: To compare the knowledge of cervical cancer and acceptability of prevention strategies among vaccinated and nonvaccinated adolescents after an HPV vaccination initiative in Eldoret, Kenya. Methods: A cross-sectional comparative study carried out in 6 public schools which were clustered into 2 groups of 2. 60 vaccinated and 120 nonvaccinated adolescents were randomly selected from each of the schools by proportionate allocation. IREC approval obtained and signed consent got from the parents. Data collection was then carried out using interviewer-administered questionnaires. Results: The median age of the participants was 14.0 (IQR: 13.0-15.0). Of 60 vaccinated adolescents, 56 (93.3%) had heard of the HPV vaccine compared with 6 (5%) of unvaccinated participants ( P < 0.001). Fifty-eight (96.7%) of vaccinated participants heard of cervical cancer compared with 61 (50.8%) unvaccinated participants ( P < 0.001). The participants were not different in their knowledge of risk factors for developing cervical cancer or its symptoms but overall, the vaccinated participants had a significantly higher knowledge score compared with the unvaccinated participants 14.4 (95% CI: 12.2-16.7). Both cohorts identified the school as the commonest source of information for health matters as compared with social media or hospitals. The 2 groups also showed similarity in their selection of cervical cancer prevention strategies acceptable to them like delaying sexual debut until after the teenage years and frequency of using barrier method for protection against sexually transmitted infections. Similar proportions of participants from both cohorts showed high acceptability of screening modalities for cervical cancer (85% vs 86.7%, P = 0.940). Of the unvaccinated participants, 63.7% expressed willingness to be vaccinated. Conclusion: Exposure to the HPV vaccine was associated with a higher knowledge of cervical cancer. The adolescents predominantly rely on the school for their information. They show remarkable acceptability for cervical cancer prevention strategies but are limited by the dearth of information they have.


2017 ◽  
Vol 94 (4) ◽  
pp. 277-283 ◽  
Author(s):  
Su Pei Khoo ◽  
Nirmala Bhoo-Pathy ◽  
Siew Hwei Yap ◽  
Mohd Khairul Anwar Shafii ◽  
Nazrilla Hairizan Nasir ◽  
...  

ObjectivesCervical cancer is a largely preventable disease, and the strategic implementation of a cervical cancer prevention programme is partly dependent on the impact of human papillomavirus (HPV) infection interpreted within the context of the country’s sociodemographic attributes. The objective of this study is to determine the prevalence of cervicovaginal HPV infection among a healthy, community-based, multiethnic Malaysian population. The HPV prevalence was subsequently correlated to the individual’s sociodemographics and sexual/reproductive history. Of significance, the observed prevalence captured was in a birth cohort not included in the national school-based HPV vaccination programme.MethodsThis was a cross-sectional study where 1293 healthy women aged between 18 and 60 years were recruited via convenience sampling from five community-based clinics in Selangor, Malaysia. Cervicovaginal self-samples were obtained and DNA was extracted for HPV detection and genotyping. A comprehensive questionnaire was administered to determine the sociodemographics and behavioural patterns of participants.ResultsThe median age at enrolment was 37 years old (IQR: 30–47). In total, 86/1190 (7.2%) of the samples collected were positive for HPV infection, with the highest HPV prevalence (11.9%) detected in the subgroup of 18–24 years old. The top three most prevalent HPV genotypes were HPV 16, 52 and 58. The independent risk factors associated with higher rates of HPV infection included Indian ethnicity, widowed status and women with partners who are away from home for long periods and/or has another sexual partner.ConclusionsThe overall prevalence of HPV infection in this Malaysian multiethnic population was 7.2%, with 6.5% being high-risk genotypes. The top three most common high-risk HPV types were HPV 16, 52 and 58. This information is important for the planning of primary (HPV vaccination) and secondary (screening) cervical cancer prevention programmes in Malaysia.


2017 ◽  
Vol 16 (2) ◽  
pp. 18-22 ◽  
Author(s):  
Andrea Obročníková ◽  
Ľudmila Majerníková

AbstractAim. Cervical cancer is the most common genital malignancy and one of the leading causes of death among female population in Slovakia. At present, this location of cancer is preventable disease visible in screening for premalignant lesions if the women use and participate in such screening regularly. We assessed the knowledge on the cervical cancer screening, the attitude towards it and its utilization among women in Slovakia.Material and methods. A cross-sectional study evaluated the knowledge, attitude and practice of cervical cancer prevention and screening among women. The sample was composed of 239 women aged 18-64 years. Data collection was conducted by selfadministered questionnaire in a period from January to April 2015.Results. Respondents exhibited an average knowledge of cervical cancer, about risk factors and early signs, but awareness of cervical cancer screening was satisfactory. Despite the fact that respondents expressed good attitude to cervical cancer screening, their level of practice was low (64% participation in preventative gynaecology check-ups and 43% in Pap smear tests within one year and 44% within three years). In the study we could observe better results in women with higher education when it comes to an illness (p < .001), its prevention (p < .001) and risk behaviour (p < .001).Conclusions. The awareness of cervical cancer among women in Slovakia is limited. In the future there is a need to educate and promote awareness of cervical cancer among women to reduce the burden of morbidity and mortality.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Petmore Zibako ◽  
Nomsa Tsikai ◽  
Sarah Manyame ◽  
Themba G. Ginindza

Abstract Background Cervical cancer (CC) morbidity and mortality is still high in developing countries like Zimbabwe. Treatment for CC is out of reach for many women, hence the need to maximise on prevention which mainly includes screening and administering human papillomavirus (HPV) vaccine. Knowledge about CC prevention is a prerequisite for utilisation of all the available options for CC prevention, yet little is known about its levels and the corresponding attitudes and practices on cancer prevention methods within the society. Methods A cross sectional survey was done to assess knowledge, attitude and practice (KAP) on CC prevention among mothers of girls aged between 9 and 14 years in Zimbabwe as well as factors explaining the KAP. Four hundred and six mothers participate. Descriptive and inferential statistics (binary logistic regression and Chi-Square test of association) were applied to determine participant characteristics with KAP using STATA version 16 software. Findings Overall KAP of cervical cancer prevention is in a poor state. The knowledge was poor with 24% being able to say CC is caused by HPV; the attitude is negative with 58% being of the opinion that CC is caused by witchcraft and it is a death sentence, while the bad practices of relying only on traditional means were being practiced. Factors associated with knowledge are: not having medical aid (odds: 0.17, 95%CI: 0.05–0.59, p = 0.005) and high levels of education (secondary level odds: 4.20; 95%CI: 2.25–7.84 p < 0.001 and tertiary odds: 7.75; 95%CI: 2.04–29.45, p-value: 0.003 compared to primary education). Attitude towards CC management was driven by levels of education (secondary level odds: 0.39, 95%CI: 0.20–0.78, p = 0.007 and tertiary odds: 0.12, 95%CI: 0.04–0.33, p < 0.001), the same factor increases odds of good practice (secondary odds: 3.78, 95%CI: 1.99–7.18, p < 0.001 and tertiary odds: 3.78, 95%CI: 1.99–7.18, p < 0.001). On the other hand, HPV vaccine knowledge was also very moderate (with majority of mothers not knowing the right age of vaccination; vaccine acceptability was high (90%), but uptake was very low (8% had their daughter vaccinated). Conclusion KAP about CC prevention was poor with factors necessary for improvement of KAP identified as education, medical insurance coverage. Making health education easily accessible in schools, primary health facilities and various media platforms will help to address the myths on causes of CC and how it can be treated. Health education and availability of free screening services and free vaccine will improve CC prevention out outcomes.


Author(s):  
Radhika M. ◽  
Sadiqunissa Sadiqunissa ◽  
Mehfooza Ahmed

Background: Cervical cancer is the most common malignancy amongst women in India. Identification and prevention of the pre-cancerous lesions helps to reduce the incidence of Carcinoma of cervix. The main aim of the study is to know the awareness and knowledge of HPV vaccine in prevention of cervical cancer among medical students.Methods: The study included 97 medical students (final year) studying in Yenepoya Medical College, Mangalore. It is a cross-sectional questionnaire-based study.Results: The results of awareness and knowledge about the HPV vaccine are interpreted in percentage. In this study, 76% of study subjects were aware that cancer cervix is preventable, 80% of the study subjects were aware about the association between the causation of cancer cervix by HPV. Majority of the study subjects about 72% ware about the vaccines for HPV but, awareness about the cost and efficacy of the vaccine was low only about 30% and 10% respectively. However, importantly students had a positive attitude to educate people regarding HPV vaccination and also to clear myths and misconceptions.Conclusions: Medical students should be educated regarding HPV infection, risk factors for causation of cervical cancer, screening methods which are available, HPV vaccines available in India and also about the efficacy and to motivate the society to have a positive attitude towards HPV vaccination by clearing the misconceptions regarding its information.


2021 ◽  
Vol 2 (3) ◽  
pp. 274-280
Author(s):  
Ritu Nayar

The approach to cervical cancer prevention has evolved significantly over the past two decades. HPV immunization has decreased the specificity of screening modalities and HPV-based testing has been replacing our previously successful morphology-only approach. Additionally, there is much more emphasis on providing precision prevention, rather than the previously used “one-fits-all” management strategies. A number of new biomarkers are entering clinical practice and being integrated into cervical cancer screening and management in order to enable a more personalized assessment of the risk for precancer/cancer for an individual patient. The 2019 ASCCP Risk-Based Management Consensus Guidelines expand on the concept of “equal management for equal risk”. They consider a patient’s history in addition to current test results to provide recommendations for increased surveillance/treatment in patients at higher risk for CIN3+ while minimizing interventions for lower-risk patients who have new versus persistent HPV infection. Clinical management decisions are based on immediate risk and 5-year risk estimates for CIN3+, which are determined by referencing an extensive risk table compiled by the National Cancer Institute (NCI). The course of action for a given patient is recommended by comparison of the risk in the risk database, to the predetermined clinical action thresholds. These guidelines address the need for simplification and offer some stability for the provider while being conducive to the incorporation of anticipated continued technologic advances in methods for cervical cancer prevention. Their enduring nature will allow for changes needed based on risk reduction as HPV vaccination uptake increases and vaccinated women reach screening age. Similarly, the design allows for the addition of new tests into the risk assessment calculations after their approval by applicable regulatory agencies and review/consensus approval by the ASCCP new technology and enduring guidelines workgroups. As cytopathologists, we must be familiar with the scientific advancements in primary and secondary prevention, evolving screening and management guidelines, and participate actively in the multidisciplinary approach for the prevention of cervical cancer.


Author(s):  
Supatmi Supatmi

AbstractBackground:  The awareness of Indonesian women to carry out early detection of cervical cancer on a regular basis have been still low. Cervical cancer can be prevented and cured by taking early detection measures because it has a long preinfassive phase. Cervical cancer prevention measures are influenced by several factors including age, education level, occupation and parity, Aims:   analyze the characteristics of women of childbearing age with cervical cancer prevention measures (HPV, IVA and Pap smear immunization) Methods: Quantitative analytic research design with cross sectional approach. The population was 193 women of fertile age in RW 9 Kelurahan Kapasan Surabaya with n Cluster Samples, the sample was 130 WUS. The research instrument used a characteristic questionnaire and cervical cancer prevention measures with a Dichotomy Question. The research variables were WUS cataristic and cervical cancer prevention behavior. Analysis with Chi-Square with a significance level of 0.05Results:  There was a relationship between age and HPV immunization (p = 0.066) and pap smear (p = 0.058), IVA action had not relationship (p = 0.770), education was related to HPV immunization (p = 0.346). IVA (0.005) was not related to pap smears = 0.603) Occupation was related to HPV immunization (p = 0.280), IVA (p = 0.000) and pap smears (p = 0.216), parity was related to HPV immunization (p = 0.003) ) and Pap smear (p = 0.117) meanwhile parity had not relationship with IVA (p = 0.839). Studying the characteristics of WUS is a first step to increase preventive efforts for cervical cancer both primary and secondary prevention   Keyword:  Characteristics of WUS, Prevention, Cervical Cancer


2021 ◽  
Vol 62 (6) ◽  
Author(s):  
Nguyen Thi Hong Hanh

Objectives: The aims of this study to assess the practice of preventing cervical cancer of 15 - 49 years old and having gynecological examination women at Lam Dong General Hospital. Research method: A cross-sectional description. Interviewed practice about cervical cancer prevention of 400 women. Results: Over the course of the study, 400 women showed the number of women who had not been vaccinated is still high at 85.5%, the rate who had not been screened for cervical cancer is 62.3%. Based on the results of the study, we recommend that reproductive age women should be communicated more frequently about HPV vaccination and periodic cervical cancer screening to prevent cervical cancer.


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