scholarly journals Effects of a physiotherapist-led approach based on a biopsychosocial model for spinal disorders: protocol for a systematic review

BMJ Open ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. e055144
Author(s):  
Takahiro Miki ◽  
Yu Kondo ◽  
Hiroshi Kurakata ◽  
Tsuneo Takebayashi ◽  
Mina Samukawa
Keyword(s):  
English Language ◽  
Long Term Effects ◽  
Short Term ◽  
Spinal Disorders ◽  
Ethical Approval ◽  
Registration Number ◽  
Randomised Controlled ◽  
Cause Of Pain

IntroductionLow back pain and neck pain are among the most common musculoskeletal disorders, and their related medical costs are rising every year. Many interventions are based on the biopsychosocial (BPS) model since the cause of pain is more multifaceted. Physiotherapists have increased opportunities to perform multidisciplinary interventions alone in clinical practice due to a lack of understanding of the model and its cost. Therefore, physiotherapist-led interventions using the BPS model are important and require an updated report summarising their effectiveness. Thus, the purpose of this study will be to summarise and synthesise the effects of physiotherapist-led interventions using the BPS model for spinal disorders.Methods and analysisWe will search the Web of Science, CENTRAL, MEDLINE, PsycINFO, CINAHL and PEDro electronic databases, using a date range from inception to September 2021. We will include only randomised controlled trials for patients diagnosed with spinal disorders who received physiotherapist-led interventions based on the BPS model. The search will be limited to English-language publications. Pain intensity and disability are the primary outcomes. Secondary outcomes are any psychological factors. We will examine the short-term, medium-term and long-term effects, and a subgroup analysis will be conducted, if possible, to investigate the role of additional physiotherapist training.Ethics and disseminationThis study is exempt from ethical approval because it involves publicly available documents. The findings will be submitted for publication in a relevant peer-reviewed journal.PROSPERO registration numberCRD42021258071.

Role of cyclic AMP in the action of dopaminergic D2 receptors of some endocrine glands in rats

1987 ◽  
Vol 7 (10) ◽  
pp. 751-755 ◽  
Author(s):  
Abdulrahim Abu-Jayyab ◽  
Ezz-Eddin S. M. El-Denshary ◽  
Abdulrahman M. Ageel ◽  
Mohamed Rafik Dakkak
Keyword(s):  
Thyroid Gland ◽  
Cyclic Amp ◽  
Adrenal Cortex ◽  
D2 Receptors ◽  
Endocrine Glands ◽  
Long Term Effects ◽  
Short Term ◽  
Presence And Absence

Short-term and long-term effects of bromocriptine mesylate (10 mg/kg i.p.) on cyclic AMP contents of the liver and some endocrine glands have been investigated in the presence and absence of sulpiride (10 mg/kg i.p.). Results revealed that bromocriptine caused significant elevations in the cyclic AMP contents of the liver and reduction in its adrenocortical content. Bromocriptine effect on the adrenal cortex was antagonized by sulpiride, whereas its effect on the liver was not changed. Bromocriptine did not change the, cyclic AMP content in the thyroid gland or the ovary.

The Role of FDI on Exports Performance: Evidence from the Mexican States

2020 ◽  
pp. 016001762097964
Author(s):  
René Cabral ◽  
Jorge Alberto Alvarado
Keyword(s):  
Panel Data ◽  
Estimation Method ◽  
Dynamic Panel Data ◽  
Border Region ◽  
Long Term Effects ◽  
Short Term ◽  
Dynamic Panel ◽  
Panel Data Methods

This article examines manufacturing export determinants across Mexican states and regions from 2007 to 2015. Paying particular attention to the role of FDI, the analysis considers internal and external determinants of manufacturing exports under static and dynamic panel data methods. Several interesting results were obtained. First, the ratio of manufacturing to total GDP is the most consistent determinant of exports performance, regardless of the estimation method or specification employed. Second, static panel data estimations under GMM techniques suggest different sensitivity to FDI across regions, with the Mexico-U.S. border region observing the most substantial short-term effect of FDI on manufacturing exports. Finally, using dynamic panel data methods, we found significant persistence and similar long-term effects of FDI across most of the regions.

Re-examining the role of benzodiazepines in the treatment of schizophrenia: A systematic review

2014 ◽  
Vol 29 (2) ◽  
pp. 212-223 ◽  
Author(s):  
Faye Sim ◽  
Isabel Sweetman ◽  
Shitij Kapur ◽  
Maxine X Patel
Keyword(s):  
Clinical Practice ◽  
First Generation ◽  
Outcome Data ◽  
Short Term ◽  
Global Improvement ◽  
Conflicting Evidence ◽  
Randomised Controlled ◽  
Long Term Studies

Background Benzodiazepine prescribing for schizophrenia occurs in clinical practice and antipsychotic trials. This review examined the clinical outcomes for benzodiazepines in schizophrenia. Method A systematic search identified randomised controlled trials that evaluated benzodiazepines in comparison with placebo or antipsychotics, and also as adjuncts to antipsychotics. Relevant clinical outcome data was extracted. Results Twenty six studies were included with some reporting multiple comparisons. Seven short-term studies compared benzodiazepines with placebo: benzodiazepine superiority was found in two out of five studies for global improvements and two out of four studies for psychiatric/behavioural outcomes. Eleven studies compared benzodiazepines with first-generation antipsychotics (FGAs): four out of nine studies (including two long-term studies) reported greater global improvements for antipsychotics; four out of five studies showed no treatment differences for psychiatric/behavioural outcomes. Fourteen studies compared benzodiazepines (as adjunct to antipsychotics) vs antipsychotics alone (mostly FGAs); benzodiazepine superiority was found for global improvement in one out of eight studies and inferiority in two out of eight short-term studies whereas superiority was found for psychiatric/behavioural outcomes in three out of 12 short-term studies and inferiority in three out of 12 studies. Conclusion Benzodiazepine superiority over placebo was found for global, psychiatric and behavioural outcomes, but inferiority to antipsychotics on longer-term global outcomes. Conflicting evidence exists regarding the addition of benzodiazepines to antipsychotics; thus the use of benzodiazepines in clinical practice and antipsychotic trials should be limited.

scholarly journals Short-term effects of a Mediterranean-style dietary pattern on cognition and mental wellbeing: A systematic review of clinical trials

2021 ◽  
pp. 1-28
Author(s):  
Latife Esgunoglu ◽  
Amy Jennings ◽  
Elizabeth Sanchia Connole ◽  
Karen Joy Murphy ◽  
Anne Marie Minihane
Keyword(s):  
Systematic Review ◽  
Dietary Pattern ◽  
Mental Wellbeing ◽  
Long Term Effects ◽  
Short Term ◽  
Ovid Medline ◽  
Quantitative Synthesis ◽  
Registration Number ◽  
Randomised Controlled ◽  
Short Term Effects

Abstract Background: Although the long-term effects of a Mediterranean-style dietary pattern (MDP) on cognition and overall mental wellbeing have been consistently described, the short-term effects of the MDP on cognitive performance, mood and anxiety have not been as widely reviewed. Objectives: The aims of this systematic review were to synthesise the evidence from randomised controlled trials (RCT) to examine whether a MDP can alter cognition and overall mental wellbeing in the short-term (up to 10 days). This will also be used to identify research gaps and to inform the design of future acute RCTs in the area. Methods: Ovid EMBASE, Ovid MEDLINE and Web of Science Core Collection were searched from inception to 8/12/2020. The data was synthesised narratively with no quantitative synthesis. The detailed protocol is available on PROSPERO, with the registration number CRD42021221085. Results: A total of 3002 studies were initially identified. After the deduplication and screening stages, 4 studies (3 articles and 1 conference proceeding) were eligible to be included. Despite the very limited data obtained, the literature suggests that a MDP can improve cognition and mood in the short-term. Specifically, improvements in attention, alertness and contentment were consistently reported. Conclusion: A MDP appears a promising strategy to improve short-term cognitive and mental health. A limitation of this review is the small number of studies identified, therefore, future studies are required to confirm these initial novel findings, and to provide granularity as to which domains are most responsive and in which population subgroups.

scholarly journals Energy Transition in Aviation: The Role of Cryogenic Fuels

Aerospace ◽  
2020 ◽  
Vol 7 (12) ◽  
pp. 181
Author(s):  
Arvind Gangoli Rao ◽  
Feijia Yin ◽  
Henri Werij
Keyword(s):  
Energy Transition ◽  
Modern Society ◽  
Liquefied Natural Gas ◽  
Long Term Effects ◽  
Short Term ◽  
Energy Carriers ◽  
The Impact ◽  
Very High

Aviation is the backbone of our modern society. In 2019, around 4.5 billion passengers travelled through the air. However, at the same time, aviation was also responsible for around 5% of anthropogenic causes of global warming. The impact of the COVID-19 pandemic on the aviation sector in the short term is clearly very high, but the long-term effects are still unknown. However, with the increase in global GDP, the number of travelers is expected to increase between three- to four-fold by the middle of this century. While other sectors of transportation are making steady progress in decarbonizing, aviation is falling behind. This paper explores some of the various options for energy carriers in aviation and particularly highlights the possibilities and challenges of using cryogenic fuels/energy carriers such as liquid hydrogen (LH2) and liquefied natural gas (LNG).

Ultrastructural investigations of MDL 19,660-induced effects on the canine platelet and megakaryocyte

1990 ◽  
Vol 48 (3) ◽  
pp. 374-375
Author(s):  
D.E. Loudy ◽  
J. Sprinkle-Cavallo ◽  
J.T. Yarrington ◽  
F.Y. Thompson ◽  
J.P. Gibson
Keyword(s):  
Antidepressant Drug ◽  
Beagle Dogs ◽  
Long Term Effects ◽  
Short Term ◽  
Platelet Counts ◽  
Toxicological Studies ◽  
Induced Aggregation ◽  
Internal Architecture

Previous short term toxicological studies of one to two weeks duration have demonstrated that MDL 19,660 (5-(4-chlorophenyl)-2,4-dihydro-2,4-dimethyl-3Hl, 2,4-triazole-3-thione), an antidepressant drug, causes a dose-related thrombocytopenia in dogs. Platelet counts started to decline after two days of dosing with 30 mg/kg/day and continued to decrease to their lowest levels by 5-7 days. The loss in platelets was primarily of the small discoid subpopulation. In vitro studies have also indicated that MDL 19,660: does not spontaneously aggregate canine platelets and has moderate antiaggregating properties by inhibiting ADP-induced aggregation. The objectives of the present investigation of MDL 19,660 were to evaluate ultrastructurally long term effects on platelet internal architecture and changes in subpopulations of platelets and megakaryocytes.Nine male and nine female beagle dogs were divided equally into three groups and were administered orally 0, 15, or 30 mg/kg/day of MDL 19,660 for three months. Compared to a control platelet range of 353,000- 452,000/μl, a doserelated thrombocytopenia reached a maximum severity of an average of 135,000/μl for the 15 mg/kg/day dogs after two weeks and 81,000/μl for the 30 mg/kg/day dogs after one week.

SUMBER-SUMBER RESILIENSI PADA REMAJA AKHIR YANG MENGALAMI KEKERASAN DARI ORANGTUA PADA MASA KANAK-KANAK

Psibernetika ◽  
2018 ◽  
Vol 11 (1) ◽  
Author(s):  
Devina Calista ◽  
Garvin Garvin
Keyword(s):  
Late Adolescents ◽  
Long Term Effects ◽  
Short Term ◽  
Parental Affection ◽  
Resilience Factors ◽  
Childhood Violence ◽  
Past Experiences ◽  
The Impact ◽  
Depth Interviews

<p><em>Child abuse by parents is common in households. The impact of violence on children will bring short-term effects and long-term effects that can be attributed to their various emotional, behavioral and social problems in the future; especially in late adolescence that will enter adulthood. Resilience factors increase the likelihood that adolescents who are victims of childhood violence recover from their past experiences</em><em>,</em><em> become more powerful individuals and have a better life. The purpose of this study was to determine the source of resilience in late adolescents who experienced violence from parents in their childhood. This research uses qualitative research methods with in-depth interviews as a method of data collection. The result shows that the three research participants have the aspects of "I Have", "I Am", and "I Can"; a participant has "I Can" aspects as a source of resilience, and one other subject has no source of resilience. The study concluded that parental affection and acceptance of the past experience have role to the three sources of resilience (I Have, I Am, and I Can)</em></p><p><em> </em></p><p><strong><em>Keyword : </em></strong><em>Resilience, adolescence, violence, parents</em></p>

Impact of FII’s and FDI’s on Indian Stock Market

2016 ◽  
Vol 1 (1) ◽  
Author(s):  
Dr. Kamlesh Kumar Shukla
Keyword(s):  
Stock Market ◽  
Financial Markets ◽  
Global Economy ◽  
Short Term ◽  
Earnings Growth ◽  
The Past ◽  
Bull Market ◽  
Indian Stock Market

FIIs are companies registered outside India. In the past four years there has been more than $41 trillion worth of FII funds invested in India. This has been one of the major reasons on the bull market witnessing unprecedented growth with the BSE Sensex rising 221% in absolute terms in this span. The present downfall of the market too is influenced as these FIIs are taking out some of their invested money. Though there is a lot of value in this market and fundamentally there is a lot of upside in it. For long-term value investors, there’s little because for worry but short term traders are adversely getting affected by the role of FIIs are playing at the present. Investors should not panic and should remain invested in sectors where underlying earnings growth has little to do with financial markets or global economy.

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