NEUTRAL FAT OF THE PERIRENAL FAT DEPOTS

1957 ◽  
Vol 35 (2) ◽  
pp. 157-160 ◽  
Author(s):  
Eldon M. Boyd ◽  
Alfred H. Lower
Keyword(s):  
Free Cholesterol ◽  
Dry Weight ◽  
Water Levels ◽  
Male Rats ◽  
Albino Rats ◽  
Cholesterol Esters ◽  
Albino Rat ◽  
Fat Depots ◽  
Males And Females ◽  
Perirenal Fat

The possibility was investigated that perirenal fat depots which have high levels of neutral fat also have high levels of phospholipid and free cholesterol associated with increased ability to actively store fat. Lipid and water levels per unit nonlipid dry weight were measured upon perirenal fat depots in 27 male and 24 female albino rats. Mean levels of water, free cholesterol, and phospholipid were significantly higher in female than in male rats. In perirenal depots containing high levels of neutral fat, (a) weights of the organ were low in females (P = 0.01 to 0.02) but not significantly so in males (P = 0.1 to 0.4), (b) levels of phospholipid were unaffected, and (c) levels of ester cholesterol, free cholesterol, and water were high in both males and females (P < 0.001 to 0.05). The results indicate that storage of increased levels of neutral fat in perirenal fat depots of the albino rat is associated with increased levels of cholesterol, cholesterol esters, and water per unit nonlipid dry weight.

NEUTRAL FAT OF THE PERIRENAL FAT DEPOTS

1957 ◽  
Vol 35 (1) ◽  
pp. 157-160
Author(s):  
Eldon M. Boyd ◽  
Alfred H. Lower
Keyword(s):  
Free Cholesterol ◽  
Dry Weight ◽  
Water Levels ◽  
Male Rats ◽  
Albino Rats ◽  
Cholesterol Esters ◽  
Albino Rat ◽  
Fat Depots ◽  
Males And Females ◽  
Perirenal Fat

The possibility was investigated that perirenal fat depots which have high levels of neutral fat also have high levels of phospholipid and free cholesterol associated with increased ability to actively store fat. Lipid and water levels per unit nonlipid dry weight were measured upon perirenal fat depots in 27 male and 24 female albino rats. Mean levels of water, free cholesterol, and phospholipid were significantly higher in female than in male rats. In perirenal depots containing high levels of neutral fat, (a) weights of the organ were low in females (P = 0.01 to 0.02) but not significantly so in males (P = 0.1 to 0.4), (b) levels of phospholipid were unaffected, and (c) levels of ester cholesterol, free cholesterol, and water were high in both males and females (P < 0.001 to 0.05). The results indicate that storage of increased levels of neutral fat in perirenal fat depots of the albino rat is associated with increased levels of cholesterol, cholesterol esters, and water per unit nonlipid dry weight.

LIPID AND WATER LEVELS IN THE KIDNEYS OF ALBINO RATS BEARING WALKER CARCINOMA 256

1956 ◽  
Vol 34 (1) ◽  
pp. 259-264 ◽  
Author(s):  
Eldon M. Boyd ◽  
Arne O. Tikkala
Keyword(s):  
Fatty Acids ◽  
Total Cholesterol ◽  
Total Lipid ◽  
Free Cholesterol ◽  
Dry Weight ◽  
Water Levels ◽  
Albino Rats ◽  
Total Fatty Acids ◽  
Wet Weight ◽  
Walker Carcinoma

The kidneys of 54 pairs of twin albino rats, one inoculated and one not inoculated with Walker carcinoma 256, were analyzed for water, total lipid, neutral fat, total fatty acids, total cholesterol, ester cholesterol, free cholesterol, and phospholipid, calculated as gm. per 100 gm. nonlipid dry weight. Compared with the kidneys of their nontumor-bearing littermates, the kidneys of tumor-bearing rats exhibited no significant change in wet weight and in concentration of total lipid, neutral fat, total fatty acids, and ester cholesterol. There was a significant increase in concentration of water, total cholesterol, free cholesterol, and phospholipid. The increase was toward concentrations of corresponding elements in Walker carcinoma 256. The changes became evident in animals bearing tumors weighing 20 to 40% or more of host weight.

MESENTERIC NEUTRAL FAT IN OBESE RATS

1958 ◽  
Vol 36 (1) ◽  
pp. 913-918
Author(s):  
Eldon M. Boyd ◽  
Eleanor M. Crandell
Keyword(s):  
Free Cholesterol ◽  
Dry Weight ◽  
Female Rats ◽  
Albino Rats ◽  
Fat Depots ◽  
Mesenteric Fat ◽  
Obese Rats ◽  
Physiologic Function ◽  
Relationship Of ◽  
The Relationship

The relationship of increasing obesity to storage of neutral fat in the mesentery was investigated in 48 albino rats. Calculated as grams per 100 g nonlipid dry weight, levels of mesenteric neutral fat were positively correlated with levels of mesenteric free cholesterol, phospholipid, and water, the correlation coefficient for water being higher in male than in female rats. These results suggest that storage of neutral fat is an active physiologic function of mesentery. On the other hand, the relative amount of body neutral fat which is stored in the mesentery became less as the animals became more obese. This indicates that in obese rats, some tissue other than mesentery is storing neutral fat at a rate greater than occurs in the mesenteric fat depots.

MESENTERIC NEUTRAL FAT IN OBESE RATS

1958 ◽  
Vol 36 (9) ◽  
pp. 913-918 ◽  
Author(s):  
Eldon M. Boyd ◽  
Eleanor M. Crandell
Keyword(s):  
Free Cholesterol ◽  
Dry Weight ◽  
Female Rats ◽  
Albino Rats ◽  
Fat Depots ◽  
Mesenteric Fat ◽  
Obese Rats ◽  
Physiologic Function ◽  
Relationship Of ◽  
The Relationship

The relationship of increasing obesity to storage of neutral fat in the mesentery was investigated in 48 albino rats. Calculated as grams per 100 g nonlipid dry weight, levels of mesenteric neutral fat were positively correlated with levels of mesenteric free cholesterol, phospholipid, and water, the correlation coefficient for water being higher in male than in female rats. These results suggest that storage of neutral fat is an active physiologic function of mesentery. On the other hand, the relative amount of body neutral fat which is stored in the mesentery became less as the animals became more obese. This indicates that in obese rats, some tissue other than mesentery is storing neutral fat at a rate greater than occurs in the mesenteric fat depots.

THE LIPID COMPOSITION AND WATER CONTENT OF BRAIN, HEART, LUNG, LIVER, GUT, AND SKIN IN THE HOST COMPONENT OF THE ALBINO RAT–WALKER CARCINOMA 256 DUAL ORGANISM

1953 ◽  
Vol 31 (6) ◽  
pp. 493-504
Author(s):  
Eldon M. Boyd ◽  
H. D. McEwen ◽  
M. N. Shanas
Keyword(s):  
Fatty Acids ◽  
Total Lipid ◽  
Free Cholesterol ◽  
Water Levels ◽  
Albino Rats ◽  
P Value ◽  
Albino Rat ◽  
Water Shift ◽  
Total Fatty Acids ◽  
Walker Carcinoma

The carcass of albino rats bearing Walker carcinoma 256 contains, at or near death of the dual organism, concentrations of lipids and water altered in the direction of the concentrations of these constituents in the tumor component. The objective of the investigation herein reported was to find the extent to which brain, heart, lung, liver, gut, and skin participated in this shift of lipid and water levels of the host carcass. Total lipid, neutral fat, total fatty acids, total cholesterol, ester cholesterol, free cholesterol, and phospholipid of these tissues were measured by oxidative micromethods in 23 albino rats bearing Walker carcinoma 256 at or near death of the dual organism. The results were expressed as gm. per 100 gm. dry weight of tissue and compared with corresponding values in 23 littermate albino rats without tumors, and differences with a P value of 0.01 or less were noted. Brain could be proved to take no part in the lipid and water shift in the carcass. Heart, lung, liver, and gut participated in the increased water shift. Liver participated in the increased free cholesterol shift. Skin and gut participated markedly in the decreased total lipid, neutral fat, and total fatty acids shift. Gut participated in the increased phospholipid shift. There were no other significant changes in lipid or water levels. These data are further evidence of the metabolism-directing influence of Walker carcinoma 256 on the host.

LIPID AND WATER LEVELS IN THE KIDNEYS OF ALBINO RATS BEARING WALKER CARCINOMA 256

1956 ◽  
Vol 34 (2) ◽  
pp. 259-264 ◽  
Author(s):  
Eldon M. Boyd ◽  
Arne O. Tikkala
Keyword(s):  
Fatty Acids ◽  
Total Cholesterol ◽  
Total Lipid ◽  
Free Cholesterol ◽  
Dry Weight ◽  
Water Levels ◽  
Albino Rats ◽  
Total Fatty Acids ◽  
Wet Weight ◽  
Walker Carcinoma

The kidneys of 54 pairs of twin albino rats, one inoculated and one not inoculated with Walker carcinoma 256, were analyzed for water, total lipid, neutral fat, total fatty acids, total cholesterol, ester cholesterol, free cholesterol, and phospholipid, calculated as gm. per 100 gm. nonlipid dry weight. Compared with the kidneys of their nontumor-bearing littermates, the kidneys of tumor-bearing rats exhibited no significant change in wet weight and in concentration of total lipid, neutral fat, total fatty acids, and ester cholesterol. There was a significant increase in concentration of water, total cholesterol, free cholesterol, and phospholipid. The increase was toward concentrations of corresponding elements in Walker carcinoma 256. The changes became evident in animals bearing tumors weighing 20 to 40% or more of host weight.

scholarly journals Effect of Tramadol on Sperm Profile of Male Albino Rats

2019 ◽  
pp. 1-6
Author(s):  
I. S. Esua ◽  
U. U. Uno ◽  
U. B. Ekaluo
Keyword(s):  
Sperm Motility ◽  
Sperm Count ◽  
Sperm Head ◽  
Male Rats ◽  
Control Group ◽  
Albino Rats ◽  
Dependent Manner ◽  
Sperm Viability ◽  
Albino Rat ◽  
Significant Difference

Background and Aim: Tramadol is a potent analgesic effective in the treatment of mild to severe pains. However, the use of the drug can pose a threat to other organs and systems. Therefore, this study evaluated the effect of graded doses of tramadol on sperm profile of male albino rats. Materials and Methods: Eighteen male rats were divided into three groups (A, B and C) using completely randomized design (CRD) with six rats in each group. Rats in group A served as the control group and were given just food and water while groups B and C were given tramadol at 50 and 100 mg/kg body weight (BW) respectively, daily for the period of 65 days. The treatment was administered via oral gavage and at the end of the treatments, the rats were sacrificed. Immediately after sacrifice, a puncture was made in the epididymis with a sterile pin and examined for semen pH. The epididymes were processed for epididymal sperm motility, viability, count and sperm head abnormality. Results: There was no significant difference in the weight of testes and semen pH. Sperm viability, sperm motility, sperm count and weight of epididymes significantly reduced (p<0.05) in tramadol treated animals when compared with the control. Results also indicated statistically significant (p<0.05) increase in sperm head abnormalities in rats treated with tramadol when compared with the control. Conclusion: The results obtained from this study reveal that tramadol has negative effects on weight of epididymes, sperm count, sperm viability, sperm motility and sperm head abnormalities in male albino rat as mammalian models in a dose dependent manner.

SIGNIFICANT CHANGES IN THE LIPID AND WATER CONTENT OF THE THYMUS GLAND IN ALBINO RATS BEARING WALKER CARCINOMA 256

1955 ◽  
Vol 33 (1) ◽  
pp. 69-82 ◽  
Author(s):  
Eldon M. Boyd ◽  
Valmore Fontaine ◽  
J. Gilbert Hill
Keyword(s):  
Fatty Acids ◽  
Tumor Growth ◽  
Total Lipid ◽  
Free Cholesterol ◽  
Dry Weight ◽  
Thymus Gland ◽  
Albino Rats ◽  
Tumor Bearing ◽  
Total Fatty Acids ◽  
Walker Carcinoma

The investigation was designed to measure hydrolipotropic variations in the thymus gland of albino rats bearing Walker carcinoma 256. This was done upon 27 pairs of littermate albino rats, one of each pair inoculated and one not inoculated with Walker carcinoma 256. The life history of the tumor was evenly represented in the series. Tumor growth was found to be accompanied by a statistically significant increase in total body weight, due to water retention, and decrease in the weight of the thymus gland. The total amount of water, dry weight, total lipid, neutral fat, total fatty acids, free cholesterol, and phospholipid were significantly less in the thymus gland of tumor-bearing albino rats. The concentrations, per unit dry weight, of total lipid, neutral fat, and total fatty acids in the thymus gland were not significantly affected by tumor growth. The similar concentrations of water, total cholesterol, free cholesterol, and phospholipid were significantly increased in the thymus gland of tumor-bearing albino rats. These changes indicated a hydrolipotropic effect of the tumor upon the thymus gland. A pyramidal, up-and-down, change in the concentrations of phospholipid and the three cholesterol fractions in the thymus gland at T/RC coefficients of 30 to 60, together with a marked loss of weight by the gland, suggested the effect upon the thymus gland of factor(s) other than the hydrolipotropic influence.

Quantitation of oxygen consumption and spontaneous muscular activity of the rat

1961 ◽  
Vol 16 (6) ◽  
pp. 982-990 ◽  
Author(s):  
Pietro O. Bramante
Keyword(s):  
Oxygen Consumption ◽  
Metabolic Rate ◽  
Basal Metabolic Rate ◽  
Muscular Activity ◽  
Male Rats ◽  
Albino Rats ◽  
Metabolic Rates ◽  
Albino Rat ◽  
Activity Data ◽  
A New Technique

Oxygen consumption (Vo2) and spontaneous muscular activity of albino rats, recorded with apparatus previously described and quantitated with a new technique, exhibited highly significant correlations when paired in successive 10-min periods with a 5-min lag of Vo2 ( y) in respect to spontaneous muscular activity ( x). Since fasting and nonfasting male rats of different weights (range: 156—462 g) showed at perfect rest a quite narrow scatter of metabolic rates ( y = yaKgb ± 6% se) and since y was linearly correlated with x (se = 7.1% fasting; 5.5% nonfasting), theoretical Vo2 values could be predicted from y = Kgyb( m + nx) when the appropriate value of b, experimentally found (in this case 0.48), was used. In two-thirds of the observations the lowest 5-min values of Vo2 did not represent the true basal metabolic rate of the animal since they coincided with variable amounts of spontaneous activity. Data show that the basal metabolic rate of the albino rat is more predictable than generally admitted. Submitted on May 26, 1961

scholarly journals Toxic effects of prolonged endosulfan exposure on some blood parameters in albino rat

1970 ◽  
Vol 5 ◽  
pp. 29-32
Author(s):  
B Das ◽  
Kawser Pervin ◽  
AK Roy ◽  
Z Ferdousi ◽  
AK Saha
Keyword(s):  
Prolonged Exposure ◽  
Treated Group ◽  
Blood Parameters ◽  
Serum Glucose ◽  
Toxic Effects ◽  
Male Rats ◽  
Albino Rats ◽  
Albino Rat ◽  
Synthetic Insecticide ◽  
Differential Counts

Endosulfan is a worldwide used synthetic insecticide that has an important role on management of pests in agriculture. The present work was undertaken to determine the effect of endosulfan on the haematological and haemochemical parameters of albino rats. Rats were feed with 5 mg/kg body weight endosulfan in mixed food stuff for 42 days. The studies were conducted on sexually matured male rats covering five groups of animals with control. Total counts of erythrocytes and haemoglobin were decreased and leucocytes were increased in treated group. Differential counts of leucocytes showed significant increase in basophils and monocytes. The levels of serum glucose, urea, creatinine and bilirubin increased significantly, suggesting that the synthetic insecticide had remarkable toxic effects on the haematological and biochemical parameters in the experimental animals. Key words: Endosulfan; prolonged exposure; haematology; haemochemical parameters; albino rat DOI: 10.3329/jles.v5i0.7346 J. Life Earth Sci., Vol. 5: 29-32, 2010

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