EFFECT OF THE ORAL ADMINISTRATION OF GLUCOSE UPON THE CONCENTRATION OF SERUM AMYLASE IN NORMAL ADULT HUMAN SUBJECTS

1949 ◽  
Vol 159 (1) ◽  
pp. 29-32 ◽  
Author(s):  
Norman P. Goldstein ◽  
Benjamin W. Smith ◽  
Jerome H. Epstein ◽  
Joseph H. Roe
Keyword(s):  
Oral Administration ◽  
Serum Amylase ◽  
Human Subjects ◽  
Normal Adult ◽  
Adult Human

scholarly journals Acceptability, Safety, and Efficacy of Oral Administration of Extracts of Black or Red Maca (Lepidium meyenii) in Adult Human Subjects: A Randomized, Double-Blind, Placebo-Controlled Study

2016 ◽  
Vol 9 (3) ◽  
pp. 49 ◽  
Author(s):  
Carla Gonzales-Arimborgo ◽  
Irma Yupanqui ◽  
Elsa Montero ◽  
Dulce Alarcón-Yaquetto ◽  
Alisson Zevallos-Concha ◽  
...  
Keyword(s):  
Oral Administration ◽  
Human Subjects ◽  
Controlled Study ◽  
Double Blind ◽  
Safety And Efficacy ◽  
Double Blind Placebo ◽  
Lepidium Meyenii ◽  
Adult Human

Transfer of oxygen, nitrogen, and carbon dioxide through normal adult human skin

1980 ◽  
Vol 49 (3) ◽  
pp. 438-443 ◽  
Author(s):  
T. N. Hansen ◽  
Y. Sonoda ◽  
M. B. McIlroy
Keyword(s):  
Carbon Dioxide ◽  
Response Times ◽  
Human Subjects ◽  
Skin Resistance ◽  
Sudden Change ◽  
Normal Adult ◽  
Similar Response ◽  
Adult Human ◽  
Transit Times ◽  
The Face

The resistance to the flow of oxygen, nitrogen, and carbon dioxide through the skin ws measured in three normal adult human subjects. A sampling chamber 2.5 cm in diameter, heated to 43-44 degrees C, was applied to the skin of the forearm and gas sampled with a mass spectrometer at a rate of about 10(-5) ml . s-1 through membranes of different resistance. Skin resistance was calculated from the results of sequential studies with different membranes of known resistance on the sampling chamber. The resistance to oxygen flow (1.79 +/- 0.92 X 10(3) atm . ml-1 . min . cm2) was 1/5 of that for nitrogen and 28.5 times that for carbon dioxide. The response time of the skin to a sudden change in arterial gas tension was investigated by having the subjects rebreathe 5% carbon dioxide in oxygen and then breathe air. The mean transit times though the skin for oxygen and carbon dioxide were similar (approx 30 s) and about twice those for nitrogen. The finding of similar response times for oxygen and carbon dioxide transfer in the face of large differences in resistance suggests that there is a high capacitance for carbon dioxide in the skin, presumably due to its high solubility and the effects of buffering.

scholarly journals CERMEP-IDB-MRXFDG: A database of 37 normal adult human brain [18F]FDG PET, T1 and FLAIR MRI, and CT images available for research

2020 ◽  
Author(s):  
Ines Merida ◽  
Julien Jung ◽  
Sandrine Bouvard ◽  
Didier Le Bars ◽  
Sophie Lancelot ◽  
...  
Keyword(s):  
Fdg Pet ◽  
Short Form ◽  
Human Subjects ◽  
Statistical Parametric Mapping ◽  
Volumetric Analysis ◽  
Ct Images ◽  
Normal Adult ◽  
Adult Human ◽  
18F Fdg ◽  
Leave One Out

We present a database of cerebral PET FDG and anatomical MRI for 37 normal adult human subjects (CERMEP-IDB-MRXFDG). Thirty-nine participants underwent [18F]FDG PET/CT and MRI, resulting in [18F]FDG PET, T1 MPRAGE MRI, FLAIR MRI, and CT images. Two participants were excluded after visual quality control. We describe the acquisition parameters, the image processing pipeline and provide participants' individual demographics (mean age 38 ± 11.5 years, range 23-65, 20 women). Volumetric analysis of the 37 T1 MRIs showed results in line with the literature. A leave-one-out assessment of the 37 FDG images using Statistical Parametric Mapping (SPM) yielded a low number of false positives after exclusion of artefacts. The database is stored in three different formats, following the BIDS common specification: 1) DICOM (data not processed), 2) NIFTI (multimodal images coregistered to PET subject space), 3) NIFTI normalized (images normalized to MNI space). Bona fide researchers can request access to the database via a short form.

scholarly journals CERMEP-IDB-MRXFDG: a database of 37 normal adult human brain [18F]FDG PET, T1 and FLAIR MRI, and CT images available for research

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Inés Mérida ◽  
Julien Jung ◽  
Sandrine Bouvard ◽  
Didier Le Bars ◽  
Sophie Lancelot ◽  
...  
Keyword(s):  
Fdg Pet ◽  
Short Form ◽  
Human Subjects ◽  
Statistical Parametric Mapping ◽  
Volumetric Analysis ◽  
Ct Images ◽  
Normal Adult ◽  
Adult Human ◽  
Leave One Out ◽  
Fdg Pet Ct

AbstractWe present a database of cerebral PET FDG and anatomical MRI for 37 normal adult human subjects (CERMEP-IDB-MRXFDG). Thirty-nine participants underwent static [18F]FDG PET/CT and MRI, resulting in [18F]FDG PET, T1 MPRAGE MRI, FLAIR MRI, and CT images. Two participants were excluded after visual quality control. We describe the acquisition parameters, the image processing pipeline and provide participants’ individual demographics (mean age 38 ± 11.5 years, range 23–65, 20 women). Volumetric analysis of the 37 T1 MRIs showed results in line with the literature. A leave-one-out assessment of the 37 FDG images using Statistical Parametric Mapping (SPM) yielded a low number of false positives after exclusion of artefacts. The database is stored in three different formats, following the BIDS common specification: (1) DICOM (data not processed), (2) NIFTI (multimodal images coregistered to PET subject space), (3) NIFTI normalized (images normalized to MNI space). Bona fide researchers can request access to the database via a short form.

THE METABOLISM OF [1,2-3H]17α-METHYLTESTOSTERONE IN HUMAN SUBJECTS

1967 ◽  
Vol 37 (1) ◽  
pp. 37-55 ◽  
Author(s):  
R. V. QUINCEY ◽  
C. H. GRAY
Keyword(s):  
Oral Administration ◽  
Intravenous Injection ◽  
Human Subjects ◽  
Adult Human

SUMMARY The metabolism of [1,2-3H] 17α-methyltestosterone (MeT) has been studied in adult human subjects, most of whom had cancer of the breast. The rates of disappearance of MeT from plasma and of the appearance of metabolites of MeT in plasma have been measured after intravenous injection of [1,2-3H]MeT. In addition, the rate of appearance of [1,2-3H]MeT and of metabolites of MeT in urine and in faeces has been measured after intravenous injection of [1,2-3H]MeT and in urine after oral administration of the steroid. The results show that MeT is metabolized more slowly than testosterone. Identification of metabolites of MeT which were isolated from the urine of patients to whom this steroid was administered has been attempted. Three compounds, 17α-methyl-5β-androstane-3α,17β-diol (tetrahydro-MeT), 17α-methyl-5α-androstane-3α,17β-diol (allotetrahydro-MeT) and unchanged MeT have been identified, three other compounds have been partially characterized and several others have been isolated. The most abundant metabolites of MeT are hydroxylated compounds reduced in ring A.

Concurrent measurements of carcinoembryonic antigen, glucosephosphate isomerase, gamma-glutamyltransferase, and lactate dehydrogenase in malignant, normal adult, and fetal colon tissues.

1980 ◽  
Vol 26 (13) ◽  
pp. 1809-1812 ◽  
Author(s):  
D D Munjal
Keyword(s):  
Colon Cancer ◽  
Lactate Dehydrogenase ◽  
Carcinoembryonic Antigen ◽  
Tumor Tissue ◽  
Human Colon ◽  
Normal Adult ◽  
Metastatic Colon Cancer ◽  
Glucosephosphate Isomerase ◽  
Adult Human ◽  
Fetal Organs

Abstract Carcinoembryonic antigen and activities of glucosephosphate isomerase (EC 5.3.1.9), γ-glutamyltransferase (EC 2.3.2.2), and lactate dehydrogenase (EC 1.1.1.27) were measured in aqueous extracts of fetal, normal adult, and malignant human colon tissues. Fetal colon, as well as primary and metastatic colon tumor tissue, showed higher activities of these analytes than did normal adult human colon. Liver metastases of colon cancer gave the highest values, normal adult human colon the lowest. Statistically, these differences were more striking in the case of carcinoembryonic antigen and glucosephosphate isomerase than for γ-glutamyltransferase or lactate dehydrogenase. In contrast to the other markers, γ-glutamyltransferase activity was lower in fetal organs than in normal adult colon and colon tumors. These results are consistent with earlier observations that activities of these markers are significantly increased in the blood of patients with metastatic colon cancer.

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