scholarly journals Pyogenic Ventriculitis ComplicatingAggregatibacter aphrophilusInfective Endocarditis: A Case Report and Literature Review

2009 ◽  
Vol 20 (3) ◽  
pp. e107-e109 ◽  
Author(s):  
Gordon W Jung ◽  
Michael D Parkins ◽  
Deirdre Church
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Infective Endocarditis ◽  
Fatal Case ◽  
Aggregatibacter Aphrophilus ◽  
Central Nervous System Penetration ◽  
Prompt Diagnosis ◽  
Ependymal Lining ◽  
Alcoholic Woman ◽  
Secondary Complication

Pyogenic ventriculitis (PV) is an uncommon, but frequently fatal infection that results from inflammation of the ventricular ependymal lining associated with a purulent ventricular system. PV has been rarely reported as a secondary complication of infective endocarditis. Prompt diagnosis and treatment with appropriate culture-directed antibiotics with adequate central nervous system penetration is crucial when managing patients who are suspected of having PV. The present study reports on a fatal case of a previously well 42-year-old alcoholic woman with infective endocarditis caused byAggregatibacter aphrophilus,with secondary brain abscess and spontaneous rupture into the ventricles causing PV.

scholarly journals Central nervous system complications of infective endocarditis.

Stroke ◽  
1991 ◽  
Vol 22 (11) ◽  
pp. 1461-1463 ◽  
Author(s):  
A V Salgado
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Infective Endocarditis

scholarly journals Does use of antiretroviral therapy regimens with high central nervous system penetration improve survival in HIV-infected adults?

HIV Medicine ◽  
2011 ◽  
Vol 12 (10) ◽  
pp. 610-619 ◽  
Author(s):  
H McManus ◽  
PCK Li ◽  
D Nolan ◽  
M Bloch ◽  
S Kiertiburanakul ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Antiretroviral Therapy ◽  
Central Nervous System Penetration

The Effect of Amitriptyline on the Central Nervous System Penetration of Methotrexate

1986 ◽  
Vol 3 (4) ◽  
pp. 219-222 ◽  
Author(s):  
RICHARD L. HEIDEMAN ◽  
FRANK M. BALIS ◽  
SOLOMON ZIMM ◽  
CYNTHIA M. LESTER ◽  
DAVID G. POPLACK
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Central Nervous System Penetration ◽  
The Central Nervous System

scholarly journals Ventriculitis Associated with Liver Abscess Caused by Klebsiella Pneumoniae

2020 ◽  
Vol 38 (3) ◽  
pp. 210-213
Author(s):  
Yongwoo Lee ◽  
Young-Mok Song
Keyword(s):  
Diabetes Mellitus ◽  
Central Nervous System ◽  
Nervous System ◽  
Klebsiella Pneumoniae ◽  
Antibiotic Treatment ◽  
Liver Abscess ◽  
Metastatic Infection ◽  
Appropriate Treatment ◽  
The Central Nervous System ◽  
Prompt Diagnosis

<i>Klebsiella pneumoniae</i> has been recognized to cause an invasive syndrome characterized by liver abscess and its metastatic infection. The characteristics of metastatic infection involving the central nervous system in this invasive syndrome are poorly understood. The authors report an 84-year-old woman with diabetes mellitus who developed liver abscess caused by <i>K. pneumoniae</i>, complicated with ventriculitis. The patient died despite the antibiotic treatment. Ventriculitis is a rare CNS complication of <i>K. pneumoniae</i> invasive syndrome and requires prompt diagnosis for the appropriate treatment.

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