scholarly journals The Relationship of Parental Reports of Smoke Exposure with the Lower Airway Microbiome and Clinical Outcomes in Critically Ill, Mechanically Ventilated Children

2020 ◽  
Author(s):  
M. Leroue ◽  
M. Sontag ◽  
K. Williamson ◽  
B. Wagner ◽  
L. Ambroggio ◽  
...  
Keyword(s):  
Clinical Outcomes ◽  
Critically Ill ◽  
Smoke Exposure ◽  
Lower Airway ◽  
Mechanically Ventilated ◽  
Airway Microbiome ◽  
Parental Reports ◽  
Relationship Of ◽  
The Relationship

scholarly journals Etiology, incidence, and outcomes of patient–ventilator asynchrony in critically-ill patients undergoing invasive mechanical ventilation

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Yongfang Zhou ◽  
Steven R. Holets ◽  
Man Li ◽  
Gustavo A. Cortes-Puentes ◽  
Todd J. Meyer ◽  
...  
Keyword(s):  
Risk Factors ◽  
Mechanical Ventilation ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Invasive Mechanical Ventilation ◽  
Surgical Intensive Care ◽  
Mechanically Ventilated ◽  
History Of ◽  
Training Background ◽  
The Relationship

AbstractPatient–ventilator asynchrony (PVA) is commonly encountered during mechanical ventilation of critically ill patients. Estimates of PVA incidence vary widely. Type, risk factors, and consequences of PVA remain unclear. We aimed to measure the incidence and identify types of PVA, characterize risk factors for development, and explore the relationship between PVA and outcome among critically ill, mechanically ventilated adult patients admitted to medical, surgical, and medical-surgical intensive care units in a large academic institution staffed with varying provider training background. A single center, retrospective cohort study of all adult critically ill patients undergoing invasive mechanical ventilation for ≥ 12 h. A total of 676 patients who underwent 696 episodes of mechanical ventilation were included. Overall PVA occurred in 170 (24%) episodes. Double triggering 92(13%) was most common, followed by flow starvation 73(10%). A history of smoking, and pneumonia, sepsis, or ARDS were risk factors for overall PVA and double triggering (all P < 0.05). Compared with volume targeted ventilation, pressure targeted ventilation decreased the occurrence of events (all P < 0.01). During volume controlled synchronized intermittent mandatory ventilation and pressure targeted ventilation, ventilator settings were associated with the incidence of overall PVA. The number of overall PVA, as well as double triggering and flow starvation specifically, were associated with worse outcomes and fewer hospital-free days (all P < 0.01). Double triggering and flow starvation are the most common PVA among critically ill, mechanically ventilated patients. Overall incidence as well as double triggering and flow starvation PVA specifically, portend worse outcome.

scholarly journals The relationship of oleic acid/albumin molar ratio and clinical outcomes in leptospirosis

Heliyon ◽  
2021 ◽  
Vol 7 (3) ◽  
pp. e06420
Author(s):  
Caroline Azevedo Martins ◽  
Maria Conceição B dos Santos ◽  
Cassiano Felippe Gonçalves-de-Albuquerque ◽  
Hugo Caire Castro-Faria-Neto ◽  
Mauro Velho Castro-Faria ◽  
...  
Keyword(s):  
Oleic Acid ◽  
Clinical Outcomes ◽  
Molar Ratio ◽  
Relationship Of ◽  
The Relationship

scholarly journals Effects of fenugreek seed powder on enteral nutrition tolerance and clinical outcomes in critically ill patients: A randomized clinical trial

2018 ◽  
Vol 5 (7) ◽  
pp. 2528-2537
Author(s):  
Akram Kooshki ◽  
Zaher Khazaei ◽  
Azam Zarghi ◽  
Mojtaba Rad ◽  
Hadi Gholam Mohammadi ◽  
...  
Keyword(s):  
Enteral Nutrition ◽  
Clinical Outcomes ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Routine Care ◽  
Fenugreek Seeds ◽  
Mechanically Ventilated ◽  
Fenugreek Seed ◽  
Group 2 ◽  
Group 1

Background: Enteral nutrition (EN) intolerance is a common complication in critically ill patients that contributes to morbidity and mortality. Based on the evidence of curing effects of fenugreek seeds in some gastrointestinal disorders, this study aimed to determine the effects of fenugreek seed powder on enteral nutrition tolerance and clinical outcomes in critically ill patients. Materials & Methods: A randomized, double-blinded clinical trial of 5-day duration was conducted on 60 mechanically ventilated patients divided in 2 groups (n=30). Group 1 was given fenugreek seed powder by gavage, twice a day in addition to routine care, while Group 2 received only routine care. Enteral nutrition tolerance and clinical outcomes were measured throughout the study. Demographic and clinical data were recorded and clinical responses to the primary outcome (enteral nutrition tolerance) and secondary outcome (other clinical factors) were interpreted. Data were analyzed using the independent t-test, Chi-squared test, covariance analysis, and repeated measure ANOVA via SPSS statistical software (v. 20); statistical significance was set at p< 0.05. Results: Patients who were fed with the fenugreek seed powder showed a significant improvement in enteral nutrition tolerance, as well as some complications of mechanical ventilation for Group 1, as compared with Group 2. The mortality rates were not different between the two groups. Conclusion: This study shows the beneficial effects of fenugreek seeds on food intolerance in critically ill patients and that the seed powder can be used as an add-on therapy with other medications. Thus, the use of fenugreek seeds to treat mechanically ventilated patients is recommended.

Genetic variants of PEAR1 and ischemic clinical outcomes in coronary artery disease patients: a systematic review and meta-analysis

2021 ◽  
Author(s):  
Xinyi Zhang ◽  
Sicong Li ◽  
Yuxuan Zhao ◽  
Ningjia Tang ◽  
Tong Jia ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Clinical Outcomes ◽  
Odds Ratio ◽  
Meta Analysis ◽  
Electronic Database ◽  
Artery Disease ◽  
Relationship Of ◽  
The Relationship ◽  
Ischemic Events

Aim: The aim of this study was to assess the association between PEAR1 polymorphisms and ischemic clinical outcomes. Materials & methods: We searched the electronic database for articles on the relationship of PEAR1 SNPs and ischemic events in patients with coronary artery disease (CAD) up to October 2020. Results: A total of 9914 patients with CAD from six studies focusing on 12 SNPs of PEAR1 were included in this study. The A allele of rs12041331 were associated with ischemic events (odds ratio: 1.40; 95% CI: 1.04–1.88; p = 0.03). The AA homozygotes of rs2768759 was related to a higher risk of ischemic events than carriers of the C allele (odds ratio: 2.08; 95% CI: 1.09–3.97; p = 0.03). Conclusion: PEAR1 rs12041331 and rs2768759 are significantly associated with ischemic events in patients with CAD.

Self-sexualization in preadolescent girls: Associations with self-objectification, weight concerns, and parent’s academic expectations

2019 ◽  
Vol 43 (6) ◽  
pp. 515-522 ◽  
Author(s):  
Christine R. Starr ◽  
Eileen L. Zurbriggen
Keyword(s):  
Self Efficacy ◽  
Academic Expectations ◽  
Weight Concerns ◽  
Social Emotional ◽  
Academic Goals ◽  
Parental Reports ◽  
Self Objectification ◽  
Relationship Of ◽  
The Relationship ◽  
Academic Self Efficacy

We investigated the relationship of self-sexualization to self-objectification, weight concerns, self-efficacy, academic outcomes, and career aspirations among preadolescent girls. Participants were 89 six- to nine-year-old girls; parental reports were also obtained. Two thirds of girls showed signs of self-sexualization by choosing a sexualized doll over a nonsexualized doll as who they preferred to look like and/or who they currently look like. Girls who self-sexualized reported higher self-objectification and weight concerns than girls who did not self-sexualize. Self-sexualization was unrelated to social, emotional, and academic self-efficacy and to girls’ career confidence and interest. However, parents of girls who self-sexualized reported their daughters had lower academic performance and enjoyed school less compared to girls who did not self-sexualize. Additionally, parents of girls who self-sexualized had lower academic expectations for their daughters. It is possible that in preadolescence self-sexualization affects girls’ body cognitions and parental expectations without (yet) affecting self-efficacy or academic goals.

scholarly journals 2315. The Relationship of Pre-Hospital Functional Status and Clinical Outcomes in Patients with Laboratory-Confirmed RSV Infection: Active Population-Based Surveillance, 2017–2019

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S794-S794
Author(s):  
Angela Branche ◽  
Lisa Saiman ◽  
Edward E Walsh ◽  
Ann R Falsey ◽  
William Sieling ◽  
...  
Keyword(s):  
Multivariate Analysis ◽  
Functional Status ◽  
Clinical Outcomes ◽  
Demographic Data ◽  
Patient Characteristics ◽  
Population Based ◽  
Active Population ◽  
Rsv Infection ◽  
Relationship Of ◽  
The Relationship

Abstract Background Respiratory syncytial virus (RSV) infection is a common cause of acute respiratory infection (ARI) in adults. Prospective surveillance enables collection of representative data on demographic and clinical characteristics. Few data of this kind are available for adults hospitalized with RSV infection. We used active population-based surveillance to identify patients with laboratory-confirmed RSV infection and evaluated demographic characteristics and clinical outcomes. Methods Hospitalized adults ≥ 18 years old residing in a predefined catchment area with ≥ 2 ARI symptoms or exacerbation of underlying cardiopulmonary disease were screened for eligibility during October 2017–April 2018 and October 2018–April 2019 in 3 hospitals in Rochester, NY and New York City. Respiratory specimens were tested for RSV using PCR assays. Clinical and demographic data were abstracted from the medical record. Multivariate analysis was used to evaluate the relationship of patient characteristics with clinical outcomes. Results 8,217 hospitalized adults were screened and 9.4% positive for RSV infection. Preliminary clinical and demographic data were available for 348 patients including 14% 18–49 years, 28% 50–64 years and 58% > 65 years. Mean age was 68 years and 60% were female (Figure 1). Patients had a mean of 3 co-morbidities, with diabetes (40%), chronic obstructive pulmonary disease (30%), chronic kidney disease (28%), congestive heart failure (28%), coronary artery disease (25%) and asthma (24%) the most common co-morbidities (Figure 2). Median hospital length of stay was 6 days (IQR 4–10), 13% of patients were admitted to the ICU, 5% were mechanically ventilated and 5% died during admission and 12% within 6 months. In multivariate analysis having > 3 comorbidities, cardiac disease or a lower baseline functional status measured by activities of daily living scores was significantly associated with 6-month mortality. Conclusion The majority of hospitalized patients with RSV infection were older adults with ≥ 3 chronic comorbid conditions. Baseline functional status may be predictive of worse clinical outcomes in patients with RSV infection. These insights into patient characteristics and clinical outcomes will provide information for prevention programs. Disclosures All authors: No reported disclosures.

scholarly journals MO066ESTABLISHING THE RELATIONSHIP OF MUSCLE STRENGTH AND MUSCLE MASS WITH 5-YEAR CLINICAL OUTCOMES IN KIDNEY TRANSPLANTATION

2016 ◽  
Vol 31 (suppl_1) ◽  
pp. i57-i58
Author(s):  
Winnie Chan ◽  
Jos Bosch ◽  
Okdeep Kaur ◽  
Anna Phillips ◽  
Richard Borrows
Keyword(s):  
Kidney Transplantation ◽  
Muscle Strength ◽  
Clinical Outcomes ◽  
Muscle Mass ◽  
Relationship Of ◽  
The Relationship

Relationship of Vitamin D Deficiency to Clinical Outcomes in Critically Ill Patients

2012 ◽  
Vol 36 (6) ◽  
pp. 713-720 ◽  
Author(s):  
David M. Higgins ◽  
Paul E. Wischmeyer ◽  
Kelly M. Queensland ◽  
Stefan H. Sillau ◽  
Alexandra J. Sufit ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Clinical Outcomes ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Relationship Of
Sign in / Sign up

Export Citation Format

Share Document