scholarly journals Myocardial Lipin 1 knockout in mice approximates cardiac effects of human LPIN1 mutations

JCI Insight ◽  
2021 ◽  
Vol 6 (9) ◽  
Author(s):  
Kari T. Chambers ◽  
Michael A. Cooper ◽  
Alison R. Swearingen ◽  
Rita T. Brookheart ◽  
George G. Schweitzer ◽  
...  
Keyword(s):  
Cardiac Effects ◽  
Lipin 1

scholarly journals Cardiac effects of activation of the parasympathetic ganglia in the third fat pad in dog hearts.

1999 ◽  
Vol 79 ◽  
pp. 100
Author(s):  
Tsuboi Masato ◽  
Furukawa Yasuyuki ◽  
Koichi Nakajima ◽  
Fumio Kurogouchi ◽  
Chiba Shigetoshi
Keyword(s):  
Fat Pad ◽  
Cardiac Effects ◽  
Parasympathetic Ganglia ◽  
The Third

scholarly journals Possible complication of bee stings and a review of the cardiac effects of bee stings

2016 ◽  
pp. bcr2015213974 ◽  
Author(s):  
Prabha Nini Gupta ◽  
B Krishna Kumar ◽  
Praveen Velappan ◽  
M D Sudheer
Keyword(s):  
Cardiac Effects

scholarly journals Differences in Cardiac Effects of Venoms from Tentacles and the Bell of Live Carukia barnesi: Using Non-Invasive Pulse Wave Doppler

Toxins ◽  
2020 ◽  
Vol 13 (1) ◽  
pp. 19
Author(s):  
Mark Little ◽  
Peter Pereira ◽  
Jamie Seymour
Keyword(s):  
Animal Models ◽  
Murine Model ◽  
Real World ◽  
Cardiac Dysfunction ◽  
Pulse Wave ◽  
Cardiac Effects ◽  
Post Exposure ◽  
Non Invasive ◽  
Cardiac Decompensation

Carukia barnesi was the first in an expanding list of cubozoan jellyfish whose sting was identified as causing Irukandji syndrome. Nematocysts present on both the bell and tentacles are known to produce localised stings, though their individual roles in Irukandji syndrome have remained speculative. This research examines differences through venom profiling and pulse wave Doppler in a murine model. The latter demonstrates marked measurable differences in cardiac parameters. The venom from tentacles (CBVt) resulted in cardiac decompensation and death in all mice at a mean of 40 min (95% CL: ± 11 min), whereas the venom from the bell (CBVb) did not produce any cardiac dysfunction nor death in mice at 60 min post-exposure. This difference is pronounced, and we propose that bell exposure is unlikely to be causative in severe Irukandji syndrome. To date, all previously published cubozoan venom research utilised parenterally administered venom in their animal models, with many acknowledging their questionable applicability to real-world envenomation. Our model used live cubozoans on anaesthetised mice to simulate normal envenomation mechanics and actual expressed venoms. Consequently, we provide validity to the parenteral methodology used by previous cubozoan venom research.

Thyroid and Cardiac Effects of Timolol in the Treatment of Hyperthyroidism

1982 ◽  
Vol 63 (3) ◽  
pp. 10P-11P ◽  
Author(s):  
F. Creagh ◽  
J. Lazarus ◽  
E. Griffiths ◽  
S. Kadury
Keyword(s):  
Cardiac Effects

scholarly journals The dependence of the cardiac effects of nifedipine on the responses of the peripheral vascular system.

Circulation ◽  
1984 ◽  
Vol 69 (5) ◽  
pp. 963-972 ◽  
Author(s):  
P B Kurnik ◽  
A J Tiefenbrunn ◽  
P A Ludbrook
Keyword(s):  
Vascular System ◽  
Peripheral Vascular ◽  
Cardiac Effects
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