Cancer Incidence in Turin: The Effect of Migration

1993 ◽  
Vol 79 (5) ◽  
pp. 304-310 ◽  
Author(s):  
Stefano Rosso ◽  
Silvia Patriarca ◽  
Piera Vicari ◽  
Roberto Zanetti
Keyword(s):  
Cancer Incidence ◽  
Southern Italy ◽  
Cancer Registries ◽  
Incidence Rates ◽  
Mortality Data ◽  
The South ◽  
Incidence Data ◽  
North East ◽  
The North ◽  
Corpus Uteri

Aims and Background Studies on migrant populations have been of great value in clarifying the role of environmental factors in cancer occurrence. Most of them consider migrants from other countries or continents. Turin, the target territory of this study, was an important area of Internal migration initially from the East, and more recently from southern Italy. Methods The study compared incidence rates (age-standardized) of the native population, of the migrants and incidence rates of the Cancer Registries located in the four main areas of origin. Results Overall incidence rates in migrants from southern Italy were intermediate compared with those of the stable populations of the South and the North. The same effect was not true for people from the North-East, who migrated in earlier decades. In this population, migration towards lower-incidence areas did not reduce cancer incidence. Migrants from the South showed a significant increase in intestinal, breast, and tobacco-related tumors compared to the stable southern population. No effect of migration was found for cancer of the mouth, pharynx, esophagus, stomach or corpus uteri. Incidence of liver cancer in migrant southern males was significantly different from the stable and the native north-western population. Conclusions The results, based on incidence data, validated previous findings based on mortality data on the effect of Italian Internal migrations and showed that migrants underwent changes in some environmental exposures. In particular, migrants from the South to the North of Italy came into contact with new risk factors, with an increase in occurrence of cancer.

scholarly journals Effect of Population-Wide Hepatitis B Vaccination in Preventing Liver Cancer Among Children and Young Adults in the United States

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 11s-11s
Author(s):  
A.Z. Shams ◽  
V. Winkler ◽  
H. Pohlabeln ◽  
V. Arndt ◽  
U. Haug
Keyword(s):  
Liver Cancer ◽  
Cancer Incidence ◽  
Cancer Registries ◽  
The United States ◽  
Incidence Rates ◽  
Age Group ◽  
Incidence Data ◽  
Hbv Vaccination ◽  
The Us ◽  
Incident Cases

Background: Liver cancer is the second most common cause of death from cancer worldwide1. In 2013, 79,2000 new cases of liver cancer and 818,000 deaths occurred globally2,3. Chronic infection with HBV accounts for at least 50% of liver cancer globally4. In the United States (US), liver cancer constitute the ninth leading cause of cancer death. The incidence of the cancer has persistently increased in the recent decades. Universal HBV vaccination was introduced in 1992 in the US. However, incidence trends of liver cancer among US children is poorly researched or relevant studies are not up-to-date5. Aim: This study aims to explore the effect of HBV population-wide vaccination program in reducing liver cancer incidence in the vaccinated children and adolescents in the US. Methods: Liver cancer incidence data were obtained from Cancer Incidence in Five Continents (CI5) databases (volumes I to X) from International Agency for Cancer Research (IARC). Data acquisition and analysis covered available incidence data between 1978-2007 from 9 cancer registries from Surveillance, Epidemiology, and End Results Program (SEER) from the US presented in the CI5 databases. Age-specific incidence rates of liver cancer (based on 5 year age groups ie 5-9 year, 10-14 year and 15-19 years) were calculated using age and sex-disaggregated incidence and population data from the SEER cancer registries. Stata software version 14.0 (StataCorp, USA) was used to calculate age-specific incidence rates, using number of liver cancer incident cases in each age group by the number of population in the respective age group. Age-specific rates were analyzed by period of diagnosis and by birth year. Rate ratios were estimated from age-group-specific Poisson regressions. Results: A total of 140 liver cancer incident cases were registered in the 9 SEER registries between 1978 to 2007 in the US. The incidence rate of liver cancer in children 5 to 9 years of age from 1978-1982 was 0.10 per 100,000 children. The incidence increased to 0.16 for the period from 2003-2007. The same trend is seen for the age group 10-14 and 15-19 years of age. Overall, age-specific incidence rates for liver cancer increased across age groups of 5-9, 10-14 and 15-19 year in the population covered by the 9 SEER registries in the US. However, risk estimates (incidence rate ratios, resulted from age-group-specific Poisson regressions did not show statistical significant effects. Conclusion: While the global response to implement population-wide HBV vaccination program is out of question, efforts to establish processes to evaluate the effect of such programs seems to be incomparably limited. Estimating the effect of HBV vaccination will relatively improve with time as further incidence data become available eg upon publication of data from new volume of CI5 databases.

scholarly journals Prediction of Cancer Incidence and Mortality in Korea, 2020

2020 ◽  
Vol 52 (2) ◽  
pp. 351-358 ◽  
Author(s):  
Kyu-Won Jung ◽  
Young-Joo Won ◽  
Seri Hong ◽  
Hyun-Joo Kong ◽  
Eun Sook Lee
Keyword(s):  
Regression Model ◽  
Cancer Incidence ◽  
Linear Trend ◽  
Cancer Control ◽  
Incidence Rates ◽  
Cancer Site ◽  
Mortality Data ◽  
Control Programs ◽  
Incidence Data ◽  
Incidence And Mortality

PurposeThis study aimed to report the projected cancer incidence and mortality for the year 2020 to estimate Korea’s current cancer burden.Materials and MethodsCancer incidence data from 1999 to 2017 were obtained from the Korea National Cancer Incidence Database, and cancer mortality data from 1993 to 2018 were acquired from Statistics Korea. Cancer incidence and mortality were projected by fitting a linear regression model to observed age-specific cancer rates against observed years and then by multiplying the projected age-specific rates by the age-specific population. A <i>Joinpoint</i> regression model was used to determine the year in which the linear trend changed significantly; we only used the data of the latest trend.ResultsIn total, 243,263 new cancer cases and 80,546 cancer deaths are expected to occur in Korea in 2020. The most common cancer site is expected to be the lung, followed by the stomach, thyroid, colon/rectum, and breast. These five cancers types are expected to represent half of the overall burden of cancer in Korea. The most common type of cancer among people who die is expected to be lung cancer, followed by liver, colon/rectal, pancreatic, and stomach cancers.ConclusionThe incidence rates for all types of cancer in Korea are estimated to decrease gradually. These up-to-date estimates of the cancer burden in Korea could be an important resource for planning and evaluating cancer-control programs.

scholarly journals Projecting Cancer Incidence for 2025 in the 2 Largest Populated Cities in Vietnam

2019 ◽  
Vol 26 (1) ◽  
pp. 107327481986527 ◽  
Author(s):  
Sang Minh Nguyen ◽  
Stephen Deppen ◽  
Giang Huong Nguyen ◽  
Dung Xuan Pham ◽  
Tung Duc Bui ◽  
...  
Keyword(s):  
Cancer Incidence ◽  
Cancer Control ◽  
Aging Population ◽  
Cancer Registries ◽  
Population Based ◽  
Incidence Rates ◽  
Cancer Site ◽  
Incidence Data ◽  
Liver Cancers ◽  
Pharynx Cancer

The population size and projected demographics of Vietnam’s 2 largest cities, Ho Chi Minh City (HCMC) and Hanoi, will change dramatically over the next decade. Demographic changes in an aging population coupled with income growth and changes in lifestyle will result in a very different distribution of common cancers in the future. The study aimed to project the number of cancer incidence in the 2 largest populated cities in Vietnam for the year 2025. Cancer incidence data from 2004 to 2013 collected from population-based cancer registries in these 2 cities were provided by Vietnam National Cancer Institute. Incidence cases in 2013 and the previous decades average annual percent changes of age-standardized cancer incidence rates combined with expected population growth were modeled to project cancer incidence for each cancer site by gender to 2025. A substantial double in cancer incidence from 2013 to 2025 resulted from a growing and aging population in HCMC and Hanoi. Lung, colorectum, breast, thyroid, and liver cancers, which represent 67% of the overall cancer burden, are projected to become the leading cancer diagnoses by 2025 regardless of genders. For men, the leading cancer sites in 2025 are predicted to be lung, colorectum, esophagus, liver, and pharynx cancer, and among women, they are expected to be breast, thyroid, colorectum, lung, and cervical cancer. We projected an epidemiological transition from infectious-associated cancers to a high burden of cancers that have mainly been attributed to lifestyle in both cities. We predicted that with 16.9% growth in the overall population and dramatic aging with these 2 urban centers, the burdens of cancer incidence will increase sharply in both cities over the next decades. Data on projections of cancer incidence in both cities provide useful insights for directing appropriate policies and cancer control programs in Vietnam.

scholarly journals Variation of Cancer Incidence between and within GRELL Countries

2021 ◽  
Vol 18 (17) ◽  
pp. 9262
Author(s):  
Paolo Contiero ◽  
Giovanna Tagliabue ◽  
Gemma Gatta ◽  
Jaume Galceran ◽  
Jean-Luc Bulliard ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cancer Incidence ◽  
Social Inequalities ◽  
Central Italy ◽  
Cancer Registries ◽  
Incidence Rates ◽  
North West ◽  
North East ◽  
Latin Language ◽  
The Difference

Variation in cancer incidence between countries and groups of countries has been well studied. However cancer incidence is linked to risk factors that may vary within countries, and may subsist in localized geographic areas. In this study we investigated between- and within-country variation in the incidence of all cancers combined for countries belonging to the Group for Cancer Epidemiology and Registration in Latin Language Countries (GRELL). We hypothesized that investigation at the micro-level (circumscribed regions and local cancer registry areas) would reveal incidence variations not evident at the macro level and allow identification of cancer incidence hotspots for research, public health, and to fight social inequalities. Data for all cancers diagnosed in 2008–2012 were extracted from Cancer Incidence in Five Continents, Vol XI. Incidence variation within a country or region was quantified as r/R, defined as the difference between the highest and lowest incidence rates for cancer registries within a country/region (r), divided by the incidence rate for the entire country/region × 100. We found that the area with the highest male incidence had an ASRw 4.3 times higher than the area with the lowest incidence. The area with the highest female incidence had an ASRw 3.3 times higher than the area with the lowest incidence. Areas with the highest male ASRws were Azores (Portugal), Florianopolis (Brazil), Metropolitan France, north Spain, Belgium, and north-west and north-east Italy. Areas with the highest female ASRws were Florianopolis (Brazil), Belgium, north-west Italy, north-east Italy, central Italy, Switzerland and Metropolitan France. Our analysis has shown that cancer incidence varies markedly across GRELL countries but also within several countries: the presence of several areas with high cancer incidence suggests the presence of area-specific risk factors that deserve further investigation.

TBE in Italy

2020 ◽  
Keyword(s):  
Surveillance System ◽  
Ad Hoc ◽  
National Level ◽  
Case Series ◽  
Incidence Rates ◽  
Mountainous Regions ◽  
North East ◽  
The North ◽  
Tick Borne Encephalitis ◽  
Low Incidence

Italy is considered a low-incidence country for tick-borne encephalitis (TBE) in Europe.1 Areas at higher risk for TBE in Italy are geographically clustered in the forested and mountainous regions and provinces in the north east part of the country, as suggested by TBE case series published over the last decade.2-5 A national enhanced surveillance system for TBE has been established since 2017.6 Before this, information on the occurrence of TBE cases at the national level in Italy was lacking. Both incidence rates and the geographical distribution of the disease were mostly inferred from endemic areas where surveillance was already in place, ad hoc studies and international literature.1

The Archaean Atâ intrusive complex (Atâ tonalite), north-east Disko Bugt, West Greenland

1999 ◽  
pp. 103-112
Author(s):  
Feiko Kalsbeek ◽  
Lilian Skjernaa
Keyword(s):  
Intrusive Complex ◽  
The South ◽  
Original Series ◽  
Early Proterozoic ◽  
West Greenland ◽  
North East ◽  
The North ◽  
Southern Border ◽  
Area North ◽  
Igneous Layering

NOTE: This article was published in a former series of GEUS Bulletin. Please use the original series name when citing this article, for example: Kalsbeek, F., & Skjernaa, L. (1999). The Archaean Atâ intrusive complex (Atâ tonalite), north-east Disko Bugt, West Greenland. Geology of Greenland Survey Bulletin, 181, 103-112. https://doi.org/10.34194/ggub.v181.5118 _______________ The 2800 Ma Atâ intrusive complex (elsewhere referred to as ‘Atâ granite’ or ‘Atâ tonalite’), which occupies an area of c. 400 km2 in the area north-east of Disko Bugt, was emplaced into grey migmatitic gneisses and supracrustal rocks. At its southern border the Atâ complex is cut by younger granites. The complex is divided by a belt of supracrustal rocks into a western, mainly tonalitic part, and an eastern part consisting mainly of granodiorite and trondhjemite. The ‘eastern complex’ is a classical pluton. It is little deformed in its central part, displaying well-preserved igneous layering and local orbicular textures. Near its intrusive contact with the overlying supracrustal rocks the rocks become foliated, with foliation parallel to the contact. The Atâ intrusive complex has escaped much of the later Archaean and early Proterozoic deformation and metamorphism that characterises the gneisses to the north and to the south; it belongs to the best-preserved Archaean tonalite-trondhjemite-granodiorite intrusions in Greenland.

scholarly journals Incidence and Trends of the Leading Cancers with Elevated Incidence Among American Indian and Alaska Native Populations, 2012–2016

2020 ◽  
Author(s):  
Stephanie C Melkonian ◽  
Hannah K Weir ◽  
Melissa A Jim ◽  
Bailey Preikschat ◽  
Donald Haverkamp ◽  
...  
Keyword(s):  
American Indian ◽  
Cancer Incidence ◽  
Alaska Native ◽  
Cancer Registries ◽  
Population Based ◽  
Incidence Rates ◽  
Breast Cancers ◽  
Age Adjusted Rates ◽  
Incident Cases ◽  
Hispanic White

Abstract Cancer incidence varies among American Indian and Alaska Native (AI/AN) populations, as well as between AI/AN and White populations. This study examined trends for cancers with elevated incidence among AI/AN compared with non-Hispanic White populations and estimated potentially avoidable incident cases among AI/AN populations. Incident cases diagnosed during 2012–2016 were identified from population-based cancer registries and linked with the Indian Health Service patient registration databases to improve racial classification of AI/AN populations. Age-adjusted rates (per 100,000) and trends were calculated for cancers with elevated incidence among AI/AN compared with non-Hispanic White populations (rate ratio &gt;1.0), by region. Trends were estimated using joinpoint regression analyses. Expected cancers were estimated by applying age-specific cancer incidence rates among non-Hispanic White populations to population estimates for AI/AN populations. Excess cancer cases among AI/AN populations were defined as observed minus expected cases. Liver, stomach, kidney, lung, colorectal and female breast cancers had higher incidence rate among AI/AN populations across most regions. Between 2012 and 2016, nearly 5,200 excess cancers were diagnosed among AI/AN populations, with the largest number of excess cancers (1,925) occurring in the Southern Plains region. Culturally informed efforts may reduce cancer disparities associated with these and other cancers among AI/AN populations.

The Metamorphosed Limestones and Associated Contaminated Igneous Rocks of the Carlingford District, Co. Louth

1932 ◽  
Vol 69 (5) ◽  
pp. 209-233 ◽  
Author(s):  
G. D. Osborne
Keyword(s):  
Igneous Rocks ◽  
The South ◽  
Ordnance Survey ◽  
Igneous Complex ◽  
North East ◽  
The North ◽  
South West ◽  
Carboniferous Limestone ◽  
Contamination Effects

THE Carlingford-Barnave district falls within the boundaries of Sheet 71 of the Ordnance Survey of Ireland, and forms part of a broad promontory lying between Carlingford Lough on the north-east and Dundalk Bay on the south-west. The greater part of this promontory is made up of an igneous complex of Tertiary age which has invaded the Silurian slates and quartzites and the Carboniferous Limestone Series. This complex has not yet been investigated in detail, but for the purposes of the present paper certain references to it are necessary, and these are made below. The prevalence of hybrid-relations and contamination-effects between the basic and acid igneous rocks of the region is a very marked feature, and because of this it has been difficult at times to decide which types have been responsible for the various stages of the metamorphism.

Taxonomy of Nystiellidae (Caenogastropoda, Epitonioidea) from Brazil, with description of three new species from the South-western Atlantic

2017 ◽  
Vol 98 (7) ◽  
pp. 1619-1644 ◽  
Author(s):  
Alexandre Dias Pimenta ◽  
Bruno Garcia Andrade ◽  
Ricardo Silva Absalão
Keyword(s):  
Rio Grande ◽  
Taxonomic Revision ◽  
South Atlantic ◽  
Shell Morphology ◽  
The South ◽  
Western Atlantic ◽  
North East ◽  
The North ◽  
Eastern Brazil ◽  
North Eastern

A taxonomic revision of the Nystiellidae from Brazil, including samples from the Rio Grande Rise, South Atlantic, was performed based on shell morphology. Five genera and 17 species were recognized. For the richest genus,Eccliseogyra, the three species previously recorded from Brazil were revised:E. brasiliensisandE. maracatu, previously known only from their respective type series, were re-examined. Newly available material ofE. maracatuexpanded the known geographic range of this species to off south-east Brazil.Eccliseogyra nitidais now recorded from north-eastern to south-eastern Brazil, as well as from the Rio Grande Rise. Three species ofEccliseogyraare newly recorded from the South Atlantic:E. monnioti, previously known from the north-eastern Atlantic, occurs off eastern Brazil and on the Rio Grande Rise; its protoconch is described for the first time, confirming its family allocation.Eccliseogyra pyrrhiasoccurs off eastern Brazil and on the Rio Grande Rise, andE. folinioff eastern Brazil. The genusIphitusis newly recorded from the South Atlantic.Iphitus robertsiwas found off northern Brazil, although the shells show some differences from the type material, with less-pronounced spiral keels. Additional new finds showed thatIphitus cancellatusranges from eastern Brazil to the Rio Grande Rise, and Iphitusnotiossp. nov. is restricted to the Rio Grande Rise.Narrimania, previously recorded from Brazil based on dubious records, is confirmed, including the only two living species described for the genus:N. azelotes, previously only known from the type locality in Florida, andN. concinna, previously known from the Mediterranean. A third species,Narrimania raquelaesp. nov. is described from eastern Brazil, diagnosed by its numerous and thinner cancellate sculpture. To the three species ofOpaliopsispreviously known from Brazil, a fourth species,O. arnaldoisp. nov., is added from eastern Brazil, and diagnosed by its very thin spiral sculpture, absence of a varix, and thinner microscopic parallel axial striae.Papuliscala nordestina, originally described from north-east Brazil, is recorded off eastern Brazil and synonymized withP. elongata, a species previously known only from the North Atlantic.

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