Community Intervention to Lower Blood Cholesterol: The "Know Your Cholesterol" Campaign in Pawtucket, Rhode Island

1986 ◽  
Vol 13 (2) ◽  
pp. 117-129 ◽  
Author(s):  
R. Craig Lefebvre ◽  
Gussie S. Peterson ◽  
Sarah A. McGraw ◽  
Thomas M. Lasater ◽  
Leslie Sennett ◽  
...  
1991 ◽  
Vol 121 (9) ◽  
pp. 1360-1365 ◽  
Author(s):  
Jacqueline K. Hundemer ◽  
Supriya P. Nabar ◽  
Brent J. Shriver ◽  
Lawrence P. Forman

2017 ◽  
Vol 4 (3) ◽  
pp. 197
Author(s):  
Dian Samitra ◽  
Zico Fakhrur Rozi

Tetracera indica Merr. locally known as Mampelas is commonly used in traditional remedies. It believed to have the potential to cure hypercholesterolemia. The potential use of this plant to lower blood cholesterol level was understudied; therefore this study aimed to determine the effect of the infusion of fresh leaves of Tetracera indica to the blood cholesterol levels of mice. This research was true experimental design, a post-test only design with nonequivalent (control) groups. This study used 25 male mice divided into five categories, i.e., P0 mice were administered with 0 g of infusion, P1 mice with 2 g infusion, P2 mice with 5 g infusion, P3 mice with 10 g infusion, and P4 mice without Tetracera indica infusion but 10 mg of simvastatin. The treatment in all categories were given continuously for seven days. The results showed the mean of the blood cholesterol levels were 169.4 ± 59.37 mg/dL in P0, 121.8 ± 7.62 mg/dL in P1, 136.2 ± 15.69 mg/dL in P2, 110.6 ± 37 , 01 mg/dL in P3 , and 179,0 ± 35,24 mg/dL in P4. Kruskal Wallis test was calculated to determine the difference of blood cholesterol level among all groups, and it reported p < 0.05. The results of this study showed that infusion of Tetracera indica leaf was significantly lowered the level of blood cholesterol in mice.


2008 ◽  
Vol 88 (2) ◽  
pp. 305-314 ◽  
Author(s):  
Christopher G Owen ◽  
Peter H Whincup ◽  
Samantha J Kaye ◽  
Richard M Martin ◽  
George Davey Smith ◽  
...  

2021 ◽  
Vol 23 (11) ◽  
Author(s):  
Umidakhon Makhmudova ◽  
P. Christian Schulze ◽  
Dieter Lütjohann ◽  
Oliver Weingärtner

Abstract Purpose of Review Coronary heart disease is the leading cause of mortality worldwide. Elevated blood cholesterol levels are not only the major but also the best modifiable cardiovascular risk factor. Lifestyle modifications which include a healthy diet are the cornerstone of lipid-lowering therapy. So-called functional foods supplemented with plant sterols lower blood cholesterol levels by about 10–15%. Recent Findings In the recent revision of the ESC/EAS dyslipidemia guideline 2019, plant sterols are recommended for the first time as an adjunct to lifestyle modification to lower blood cholesterol levels. However, the German Cardiac Society (DGK) is more critical of food supplementation with plant sterols and calls for randomized controlled trials investigating hard cardiovascular outcomes. An increasing body of evidence suggests that plant sterols per se are atherogenic. Summary This review discusses this controversy based on findings from in vitro and in vivo studies, clinical trials, and genetic evidence.


1991 ◽  
Vol 91 (9) ◽  
pp. 1113-1115
Author(s):  
Jane Owens Key ◽  
Albert P. Rocchini

2016 ◽  
Vol 48 (4) ◽  
pp. 359-366 ◽  
Author(s):  
Linda M Boettger ◽  
Rany M Salem ◽  
Robert E Handsaker ◽  
Gina M Peloso ◽  
Sekar Kathiresan ◽  
...  

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